Find Luxury Hotels in St. Charles, MO

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Check availability on St. Charles Luxury Hotels

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Compare St. Charles Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1002)
"Everything was very clean, restaurants were good, and staff was awesome."
The price is AED 621
AED 787 total
includes taxes & fees
11 May - 12 May
Ameristar Casino Resort and Spa

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Location and garage parking. Easy to move in and around area. Beautiful setting,felt very safe. "
The price is AED 418
AED 481 total
includes taxes & fees
18 May - 19 May
Country Inn & Suites by Radisson, St. Charles Historic District

Relax Inn Saint Charles

2.0 star property
6.4 out of 10, (850)
"It was what you would expect for the price...no frills but fine for a night."
The price is AED 248
AED 285 total
includes taxes & fees
7 May - 8 May
Relax Inn Saint Charles

Baymont by Wyndham St. Charles

2.5 star property
8.2 out of 10, Very Good, (1000)
"The staff was very friendly and helpful, and I will stay at this hotel again."
Baymont by Wyndham St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1133)
"Great staff, fantastic hotel. "
The price is AED 509
AED 585 total
includes taxes & fees
18 May - 19 May
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels can I expect to find in St. Charles?
Lie in the lap of luxury during your getaway to St. Charles in one of Expedia’s 6 luxury hotels.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you’re in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.