Find Luxury Hotels in St. Charles, MO

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on St. Charles Luxury Hotels

Tonight
30 Mar - 31 Mar
Tomorrow
31 Mar - 1 Apr
Next weekend
4 Apr - 6 Apr
In two weeks
11 Apr - 13 Apr

Compare St. Charles Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Ameristar Casino Resort and Spa
Casino

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1153)
"Property beautiful wonder stay "
The price is AED 621
AED 787 total
includes taxes & fees
31 Mar - 1 Apr
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District
Desk, laptop workspace, blackout drapes, iron/ironing board

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1156)
"Very nice & clean"
The price is AED 418
AED 481 total
includes taxes & fees
6 Apr - 7 Apr
Country Inn & Suites by Radisson, St. Charles Historic District
Relax Inn Saint Charles
Lobby

Relax Inn Saint Charles

2.0 star property
6.4 out of 10, (807)
"I am happy and satisfied "
The price is AED 231
AED 266 total
includes taxes & fees
31 Mar - 1 Apr
Relax Inn Saint Charles
Baymont by Wyndham St. Charles
Lobby

Baymont by Wyndham St. Charles

2.5 star property
8.0 out of 10, Very Good, (1095)
"Staff was wonderful! Part of the property is under construction, but that didn't bother us at all. The beds were super comfy, and the room was very clean. Overall the property is older and some places show it, but a great value and comfortable stay! "
The price is AED 264
AED 304 total
includes taxes & fees
13 Apr - 14 Apr
Baymont by Wyndham St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Lobby

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1379)
"Overall a good experience. Good breakfast buffet with omelet being made for you. Overall cleanliness was good. They had difficulty keeping the pool available with the right chemical balance."
The price is AED 509
AED 585 total
includes taxes & fees
6 Apr - 7 Apr
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in St. Charles

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels can I expect to find in St. Charles?
Lie in the lap of luxury during your getaway to St. Charles in one of Expedia’s 6 luxury hotels.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you’re in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.