Find 5 Star Hotels in St. Charles, MO from AED 353
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on St. Charles 5 Star Hotels
Compare St. Charles 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (997)
The price is AED 1,545
AED 1,807 total
includes taxes & fees
29 Apr - 30 Apr
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (529)
The price is AED 2,127
AED 2,477 total
includes taxes & fees
27 Apr - 28 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Charles.
Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
The price is AED 419 per night from May 22 to May 23
AED 419
AED 494 total
includes taxes & fees
22 May - 23 May
8.4/10 Very Good! (3,636 reviews)
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about St. Charles
Explore St. Charles: its history, live music, food, and more!
Explore a world of travel with Expedia
Explore a world of travel with Expedia
St. Charles Hotels by Star Rating
Hotels in St. Charles Neighborhoods
Stay near popular St. Charles attractions
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Historic Main Street
- Hotels near Lindenwood University
- Hotels near Family Arena
- Hotels near Katy Trail
- Hotels near Fast Lane Classic Cars
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near Jaycee Park
- Hotels near Enterprise Center
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near City Museum
More Hotel Options in St. Charles
- Adventure Hotels in St. Charles
- Business Hotels in St. Charles
- Casinos in St. Charles
- Cheap Hotels in St. Charles
- Family Hotels in St. Charles
- Golf Hotels in St. Charles
- Historic Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotel with a Concierge in St. Charles
- Hotels with Bars in St. Charles
- Hotels with Free Parking in St. Charles
- Hotels with Hot Tubs in St. Charles
- Hotels with WiFi in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Hotels with smoking rooms in St. Charles
- Luxury Hotels in St. Charles
- Pet-friendly Hotels in St. Charles
- Resorts & Hotels with Spas in St. Charles
- Romantic Hotels in St. Charles
- Shopping Hotels in St. Charles
- Winery Hotels in St. Charles
Explore more hotels
- Clayton Plaza Hotel & Extended Stay
- Hollywood Casino & Hotel St. Louis
- River City Casino & Hotel
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Le Méridien St. Louis Clayton
- Moonrise Hotel
- Drury Inn & Suites St. Louis Union Station
- 21C Museum Hotel St Louis
- Live by Loews - St.Louis
- Hilton St. Louis at the Ballpark
- Casino Queen Hotel
- Hilton St. Louis Airport
- The Wildwood Hotel
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Embassy Suites by Hilton St. Louis Downtown
- Best Western St. Louis-Kirkwood Route 66
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Pear Tree Inn St. Louis Near Union Station
- The West End