Find 5 Star Hotels in Lake Nona Medical City, FL from AED 291

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Compare Lake Nona Medical City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

5.0 star property
9.4 out of 10, Exceptional, (147)
"Great place to stay with family "
The price is AED 1,172
AED 1,496 total
includes taxes & fees
16 Dec - 17 Dec
Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

5.0 star property
9.6 out of 10, Exceptional, (808)
"Everyone is very helpful and curious Thank you . "
The price is AED 3,581
AED 3,948 total
includes taxes & fees
15 Dec - 16 Dec
Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

The Ritz-Carlton Orlando, Grande Lakes

5.0 star property
9.2 out of 10, Wonderful, (1030)
"I wish I could give more stars. Worth every penny for service and ambience. Lovely room, grounds, service, meals, people, everything!"
The price is AED 2,347
AED 2,824 total
includes taxes & fees
16 Dec - 17 Dec
The Ritz-Carlton Orlando, Grande Lakes

Conrad Orlando

5.0 star property
9.4 out of 10, Exceptional, (144)
"Beautiful place"
The price is AED 1,895
AED 2,268 total
includes taxes & fees
28 Nov - 29 Nov
Conrad Orlando

ette hotel

5.0 star property
9.8 out of 10, Exceptional, (226)
"Great experience overall, the staff was friendly and helpful there is a staff member that has gone above and beyond and his name is Lucciano, amazing service and dedication. He had an unmatched level of service and attention to detail! Thank you."
The price is AED 1,461
AED 1,658 total
includes taxes & fees
9 Dec - 10 Dec
ette hotel

Reunion Resort & Golf Club

5.0 star property
8.6 out of 10, Excellent, (1182)
"My husband enjoyed golfing the Nicklaus golf course. Small challenging greens. "
The price is AED 719
AED 966 total
includes taxes & fees
29 Nov - 30 Nov
Reunion Resort & Golf Club

Encore Resort at Reunion

5.0 star property
8.4 out of 10, Very Good, (887)
"It was great"
Encore Resort at Reunion

Family Friendly Four Bedroom w GameRoom @Disney 5145

5.0 star property
10.0 out of 10, Exceptional, (3)
"It was fantastic!"
Family Friendly Four Bedroom w GameRoom @Disney 5145

Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131

5.0 star property
10.0 out of 10, Exceptional, (1)
"La propiedad es muy linda y cómoda , ideal para disfrutar en familia . La habitación de los niños hermosa decorada con Toy Story , a mis niños les encantó "
Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131

Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191

5.0 star property
Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191

Gorgeous 2 Bedroom Apartment Close to Disney 305 3191

5.0 star property
8.0 out of 10, Very Good, (3)
"Es war dunkel bei der Ankunft und wir konnten die Nummern an den Gebäuden in der riesigen Anlage nicht erkennen. Der Herr an der Torschranke hat es zweimal falsch erklärt. "
Gorgeous 2 Bedroom Apartment Close to Disney 305 3191

Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629

5.0 star property
Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629

Margarita Porch Paradise

5.0 star property
10.0 out of 10, Exceptional, (1)
"The house was beautiful and comfortable for our family, we would have stayed longer! The resort is fun, plenty of stores and good restaurants. We will definitely come back. "
Margarita Porch Paradise

Free Resort Access 4 Bedroom Near Disney with Themed Rooms

5.0 star property
9.2 out of 10, Wonderful, (31)
"Perfect location for 192, All Disney and Universal. 20 mins max. Pool fab, local restaurants and services perfect. Easy slept 2 families. Good facilities throughout the Villa. "
Free Resort Access 4 Bedroom Near Disney with Themed Rooms

7 Bedroom Villa, Private Pool, Resort Amenities

5.0 star property
9.0 out of 10, Wonderful, (10)
"Amazing!! Booked for 8 days as part of a 2 week family summer holiday. It's outstanding. It's in a great location & beautifully presented. There were only 3 of us but there was more than enough space for 3 families. The communication leading up to the stay & during was faultless, there were a few lights out in the pool area, I messaged in the morning to let the host know & they were there in the afternoon, great service. We took 2 days to relax here before the parks, the pool is a great...
7 Bedroom Villa, Private Pool, Resort Amenities

Splendid 5Bd Close to Disney at Storey Lake 4251

5.0 star property
9.2 out of 10, Wonderful, (5)
"Everything from the house to the property was amazing!!! the only downside is entering the property. cars were backed up for at least half a mile and it took a long time to get in every time we returned from an outing. My husband had an argument with the security guard because his pass was not scanning so he was told he could not come in. They really need to come up with a better check in system."
Splendid 5Bd Close to Disney at Storey Lake 4251

5126 Compass Bay Resort Orlando 4Bedrooms Close to Disney

5.0 star property
9.6 out of 10, Exceptional, (4)
"Excellent house only 10 mins from Disney. Nice gated community with a communal pool and child’s play area. The house was very clean and very comfortable. Would definitely stay there again."
5126 Compass Bay Resort Orlando 4Bedrooms Close to Disney

Luxury 8Bd with Pool @ Sonoma Resort 2639

5.0 star property
2.0 out of 10, (1)
"The property had 8 bedrooms, only 2 were king size. All the beds are so low to the ground. The refrigerator was broken. The coffee table was broken. They charge a massive deposit. Then they send you an email after check out that they deducted money from your deposit and say that you have things damaged. I called the first day to tell them the defects and no one response. I wonder never recommend this place. "
Luxury 8Bd with Pool @ Sonoma Resort 2639

The Ritz-Carlton Residences Orlando, Grande Lakes

5.0 star property
The Ritz-Carlton Residences Orlando, Grande Lakes

Gorgeous 4Bd with Pool @ Storey Lake Resort 4475

5.0 star property
9.0 out of 10, Wonderful, (2)
Gorgeous 4Bd with Pool @ Storey Lake Resort 4475
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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lake Nona Medical City?
There are a range of pricing options for 5-star hotels in Lake Nona Medical City on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare all of the available accommodations for your chosen dates and make use of our pricing and other filters to lock in the ideal high-end stay.

  • Search for the lowest price per night from AED 291

What makes a hotel 5 stars in Lake Nona Medical City?
From high-end dining venues and all-day fitness centers to swimming pools and luxury bedding, the 5-star experience in Lake Nona Medical City is all about indulgence and comfort. But it calls for more than just upscale conveniences to get a 5-star rating. Stays also have to deliver superior guest-focused services like in-room massage treatments, laundry and dry cleaning and 24-hour room service.
Are there any 5-star all-inclusive resorts in Lake Nona Medical City?
Expedia’s filter tool is the quickest way to narrow down what you want. Select “All inclusive” and “5-star” to see the most upscale resorts in Lake Nona Medical City where your room, meals, activities and entertainment are included in the upfront price. At these getaways, your vacation is pure leisure from the moment you put down your suitcase.
Are there any 5-star vacation rentals in Lake Nona Medical City?
Our site doesn’t offer any 5-star vacation rentals in Lake Nona Medical City. However, you can still find some top-rated escapes where the only item on your agenda will be to kick back and enjoy yourself. Discover what’s available by searching through our vacation rentals in Lake Nona Medical City.