Find 5 Star Hotels in Florida Keys from AED 966

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Compare Florida Keys 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Isla Bella Beach Resort & Spa
Beach

Isla Bella Beach Resort & Spa

5.0 star property
9.0 out of 10, Wonderful, (1006)
"The property is very quiet and easy to get to restaurants."
The price is AED 1,319
AED 1,719 total
includes taxes & fees
15 Jan - 16 January 2025
Isla Bella Beach Resort & Spa
Cheeca Lodge & Spa
Pool

Cheeca Lodge & Spa

5.0 star property
9.0 out of 10, Wonderful, (1006)
"Excellent vacation resort"
The price is AED 966
AED 1,335 total
includes taxes & fees
8 Jan - 9 January 2025
Cheeca Lodge & Spa
Little Palm Island Resort & Spa - A Noble House Resort
Property grounds

Little Palm Island Resort & Spa - A Noble House Resort

5.0 star property
9.8 out of 10, Exceptional, (42)
"fabulous accommodation and staff...service is superb"
Little Palm Island Resort & Spa - A Noble House Resort
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd, Marathon, FL
The price is AED 1,218 per night from Dec 25 to Dec 26
AED 1,218
AED 1,597 total
includes taxes & fees
25 Dec - 26 Dec
7.8/10 Good! (1,005 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
The amount you pay for a 5-star hotel in Florida Keys can vary depending on the time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.

  • Search for the lowest price per night from AED 1,044

What makes a hotel 5 stars in Florida Keys?
In Florida Keys, a hotel needs to provide a specific level of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You’ll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer special touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Keys?
Expedia’s filters are the best way to narrow down what you’re looking for. Select “5-star” and “All inclusive” to see the most luxurious properties in Florida Keys where your meals, room, activities and entertainment are included in the price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.
Are there any 5-star vacation rentals in Florida Keys?
There are no 5-star vacation rentals in Florida Keys on our site, but there are a range of other top-rated properties worth checking out. Search through our vacation rentals in Florida Keys to book the best place for your stay.