Find 5 Star Hotels in Florida Keys from AED 1,154

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Check availability on Florida Keys 5 Star Hotels

Tonight
27 Mar - 28 Mar
Tomorrow
28 Mar - 29 Mar
This weekend
28 Mar - 30 Mar
Next weekend
4 Apr - 6 Apr

Compare Florida Keys 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Cheeca Lodge & Spa
Private beach, sun loungers, beach umbrellas, beach towels

Cheeca Lodge & Spa

5.0 star property
9.0 out of 10, Wonderful, (1093)
"Wonderful stay - beautiful grounds "
The price is AED 1,290
AED 1,699 total
includes taxes & fees
27 Apr - 28 Apr
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa
Property grounds

Isla Bella Beach Resort & Spa

5.0 star property
9.0 out of 10, Wonderful, (1083)
"Rooms and resort were very nice, staff was helpful and friendly, plenty of pools and very relaxing spa!"
The price is AED 1,202
AED 1,583 total
includes taxes & fees
27 Apr - 28 Apr
Isla Bella Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd, Marathon, FL
The price is AED 1,277 per night from Apr 2 to Apr 3
AED 1,277
AED 1,693 total
includes taxes & fees
2 Apr - 3 Apr
7.8/10 Good! (989 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Swim with dolphins, snorkel over coral reefs, visit Ernest Hemingway’s home or just relax on a beach and enjoy the balmy climate of this beautiful group of islands.

See all hotels in Florida Keys
Higgs Beach showing a sandy beach and tropical scenes as well as a large group of people

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
The amount you pay for a 5-star hotel in Florida Keys can vary depending on the time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.

  • Search for the lowest price per night from AED 1,154

What makes a hotel 5 stars in Florida Keys?
In Florida Keys, a hotel needs to provide a specific level of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You’ll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer special touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Keys?
Expedia’s filters are the best way to narrow down what you’re looking for. Select “5-star” and “All inclusive” to see the most luxurious properties in Florida Keys where your meals, room, activities and entertainment are included in the price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.
Are there any 5-star vacation rentals in Florida Keys?
There are no 5-star vacation rentals in Florida Keys on our site, but there are a range of other top-rated properties worth checking out. Search through our vacation rentals in Florida Keys to book the best place for your stay.