Find hotels in Upstate South Carolina, SC from AED 250
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Compare 2,597 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Abernathy of Clemson
The Abernathy of Clemson
9.6 out of 10, Exceptional, (497)
The price is AED 694
AED 771 total
includes taxes & fees
31 Mar - 1 Apr

Hotel Hartness
Hotel Hartness
9.8 out of 10, Exceptional, (484)
The price is AED 542
AED 720 total
includes taxes & fees
20 Apr - 21 Apr

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference Center
8.8 out of 10, Excellent, (1212)
The price is AED 461
AED 523 total
includes taxes & fees
17 Apr - 18 Apr

Hampton Inn & Suites Greenville Airport, SC
Hampton Inn & Suites Greenville Airport, SC
9.2 out of 10, Wonderful, (865)
The price is AED 384
AED 435 total
includes taxes & fees
19 Apr - 20 Apr

Comfort Suites Anderson-Clemson
Comfort Suites Anderson-Clemson
8.4 out of 10, Very Good, (969)
The price is AED 426
AED 473 total
includes taxes & fees
13 Apr - 14 Apr

The Inn at Patrick Square
The Inn at Patrick Square
9.8 out of 10, Exceptional, (697)
The price is AED 657
AED 730 total
includes taxes & fees
31 Mar - 1 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Upstate South Carolina, SC
Showing deals for:Apr 11 - Apr 13
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The Westin Poinsett Greenville
Greenville
9.2/10Wonderful (1,062 reviews)
15% off
Price is AED 1,105
per night
AED 2,504 total
includes taxes & fees
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Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism
Where to stay in Upstate South Carolina
Where to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

Greenville Downtown
2 out of top 10 points of interest in this area
5/5(654 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
More cheap stays in Upstate South Carolina
More cheap stays in Upstate South Carolina

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
The price is AED 340 per night from Apr 1 to Apr 2
AED 340
AED 378 total
includes taxes & fees
1 Apr - 2 Apr
8.2/10 Very Good! (1,000 reviews)
Hotels in Upstate South Carolina with star-rating
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
13 properties
Stay near popular Upstate South Carolina attractions
Stay near popular Upstate South Carolina attractions

Clemson University
5/5(410 reviews)
Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.
Recent reviews of Upstate South Carolina hotels
Recent reviews of Upstate South Carolina hotels

Hyatt Place Greenville/Downtown
5/5 Excellent
"Clean and inviting."
A verified traveler stayed at Hyatt Place Greenville/Downtown
Posted 1 day ago
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Stay near popular Upstate South Carolina attractions
- Hotels near Clemson University
- Hotels near BMW Performance Center
- Hotels near Haywood Mall
- Hotels near Lake Jocassee
- Hotels near Falls Park on the Reedy
- Hotels near Bon Secours Wellness Arena
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Greenville Convention Center
- Hotels near The Peace Center
- Hotels near Bob Jones University
- Hotels near Wofford College
- Hotels near Devils Fork State Park
- Hotels near Fred W. Symmes Chapel
- Hotels near Anderson University
- Hotels near WestGate Mall
- Hotels near Fluor Field at the West End
- Hotels near Table Rock State Park
- Hotels near Memorial Stadium
- Hotels near Converse College
- Hotels near Spartanburg Memorial Auditorium
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Hotels near Upstate South Carolina Airports
Upstate South Carolina Hotels by Brand
Other Hotels near Upstate South Carolina, South Carolina
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Explore more hotels
- Hilton Greenville
- Quality Inn & Suites Greenville - Haywood Mall
- Hyatt Place Greenville/Haywood
- Holiday Inn Greenville - Woodruff Road by IHG
- Lakeside Lodge Clemson
- Best Western Greenville Airport Inn
- Baymont by Wyndham Greenville Woodruff Rd
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- Wooded Cottage - 3 Mi to Clemson University