Photo by Cindy Keese

Find hotels in Seneca, SC from AED 212

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Compare 1,547 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (832)
"Great place"
The price is AED 400
AED 494 total
includes taxes & fees
8 Apr - 9 Apr
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (693)
"Rooms are so small, and does not have any closets. "
The price is AED 426
AED 469 total
includes taxes & fees
13 Apr - 14 Apr
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (587)
"Very clean and the staff is very helpful"
The price is AED 445
AED 490 total
includes taxes & fees
27 Apr - 28 Apr
Hampton Inn & Suites Seneca-Clemson Area

Quality Inn Seneca US-123

2.5 star property
8.0 out of 10, Very Good, (576)
"Clean and efficient somewhat dated"
The price is AED 305
AED 373 total
includes taxes & fees
21 Apr - 22 Apr
Quality Inn Seneca US-123

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (580)
"Very clean rooms, and nice staff."
The price is AED 328
AED 361 total
includes taxes & fees
13 Apr - 14 Apr
Best Western Seneca-Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (137)
"Nice Room , friendly staff , nice and clean breakfast bar! "
The price is AED 474
AED 521 total
includes taxes & fees
8 Apr - 9 Apr
Fairfield Inn & Suites Seneca Clemson Univ Area

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (4)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"
The price is AED 331
AED 364 total
includes taxes & fees
21 Apr - 22 Apr
Postcard Cabins Lake Hartwell

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (665)
"Good "
The price is AED 253
AED 278 total
includes taxes & fees
13 Apr - 14 Apr
Days Inn by Wyndham Seneca / Clemson Area

Baymont by Wyndham Easley/Greenville

2.5 star property
7.2 out of 10, Good, (648)
"Me and my girlfriend stayed here for a couple nights in a king suite. The bed was very comfy and water pressure, and hot water felt great during my stay. Staff are very friendly. Overall great stay would highly recommend. "
The price is AED 311
AED 345 total
includes taxes & fees
13 Apr - 14 Apr
Baymont by Wyndham Easley/Greenville

Quality Inn & Suites Easley - Greenville

2.5 star property
7.0 out of 10, Good, (344)
"This location is a typical older style motel where the room connects to the outside sidewalk. If you’re trying to compare this location to a Marriott somewhere, then of course this location is going to fail. Putting this Quality Inn in the same box, however with other similar motels, I think it was perfectly fine. We had no complaints. Yes, some of the tile in the bathroom was aging, but we found the room clean, the beds were comfortable, the price was reasonable, and the breakfast was pretty...
The price is AED 309
AED 343 total
includes taxes & fees
13 Apr - 14 Apr
Quality Inn & Suites Easley - Greenville

Days Inn by Wyndham Easley/Greenville/Clemson Area

2.0 star property
6.2 out of 10, (722)
"Everything was fine "
The price is AED 255
AED 283 total
includes taxes & fees
10 Apr - 11 Apr
Days Inn by Wyndham Easley/Greenville/Clemson Area

Hampton Inn Anderson/ Alliance Business Park

2.5 star property
9.2 out of 10, Wonderful, (746)
"We were here for just a short stay while we visited Disneyland. The room was an excellent place to rest our heads for the night. Parking was super convenient. The hotel beds were comfortable. We enjoyed the breakfast the next morning before leaving. Would recommend to anyone visiting the Disneyland area. "
The price is AED 393
AED 437 total
includes taxes & fees
18 Apr - 19 Apr
Hampton Inn Anderson/ Alliance Business Park

Holiday Inn Express Anderson by IHG

2.5 star property
8.6 out of 10, Excellent, (362)
"Easy transaction. Great customer service."
The price is AED 410
AED 455 total
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn Express Anderson by IHG

The Bleckley Inn

3.5 star property
9.8 out of 10, Exceptional, (394)
"Such a quaint nice hotel. Charm, cleanliness, location, convenience, staff all so good. Only negative was mattress was very uncomfortable and quite ‘springy and squeaky when sitting or turning over. "
The price is AED 679
AED 754 total
includes taxes & fees
9 Apr - 10 Apr
The Bleckley Inn

Home2 Suites by Hilton Anderson Downtown

3.0 star property
9.2 out of 10, Wonderful, (156)
"Clean well laid out rooms, full kitchen, keurig; easy parking, walkable location, restaurants nearby. Would love if the bathroom had a fan."
The price is AED 526
AED 583 total
includes taxes & fees
20 Apr - 21 Apr
Home2 Suites by Hilton Anderson Downtown

Horizon Inn & Suites

2.0 star property
5.0 out of 10, (129)
"It was all around a nice stay with the exception of there was no remote or shower curtain"
The price is AED 212
AED 247 total
includes taxes & fees
8 Apr - 9 Apr
Horizon Inn & Suites

Super 8 by Wyndham Anderson/Clemson Area

2.5 star property
6.6 out of 10, (208)
"Very friendly and clean"
The price is AED 257
AED 285 total
includes taxes & fees
8 Apr - 9 Apr
Super 8 by Wyndham Anderson/Clemson Area

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (818)
"Enjoyed my stay, however there isn't a channel list for the TV so you have to search around for something to watch. "
The price is AED 250
AED 278 total
includes taxes & fees
13 Apr - 14 Apr
Quality Inn Clemson near University

Holiday Inn Anderson by IHG

3.0 star property
8.8 out of 10, Excellent, (638)
"Nice decor and bath products; friendly and helpful staff. Would have like to have access to filtered water stations and complimentary coffee/tea in lobby w/o purchasing breakfast. In-room Keurig was not clean and very dusty. "
The price is AED 452
AED 501 total
includes taxes & fees
18 Apr - 19 Apr
Holiday Inn Anderson by IHG

Americas Best Value Inn Anderson, SC

2.0 star property
5.6 out of 10, (133)
"Stay here few times an love it. Clean friendly an quiet"
The price is AED 247
AED 274 total
includes taxes & fees
1 May - 2 May
Americas Best Value Inn Anderson, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Seneca

Escape to Seneca! Enjoy its sports, lake views, and coffee.

View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

What's the top vacation rental in Seneca?

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub: Visitors give good reviews to this Seneca vacation home rental, which is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with an arcade game room and a hot tub. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and 4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. . See all vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best place to stay for a family vacation to Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.

What's the best LGBTQ-friendly place to stay in Seneca?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn & Suites Seneca-Clemson Area is another good choice for your stay.

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Quality Inn Seneca US-123 and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 276 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.