Search Guest Houses in Upstate South Carolina
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Compare 8 Guest Houses in Upstate South Carolina with updated reviews, rates, and availability.

✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.
✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.
10.0 out of 10, Exceptional, (65)

Private Suite in Downtown Simpsonville
Private Suite in Downtown Simpsonville
10.0 out of 10, Exceptional, (57)

Peaceful Lakefront Getaway Close to Clemson
Peaceful Lakefront Getaway Close to Clemson
10.0 out of 10, Exceptional, (33)

Poolside Mountain Views and Outdoor Living
Poolside Mountain Views and Outdoor Living
10.0 out of 10, Exceptional, (28)

Light and airy contemporary guest house with private deck and parking.
Light and airy contemporary guest house with private deck and parking.
10.0 out of 10, Exceptional, (31)

Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.
Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.
9.2 out of 10, Wonderful, (17)

Downtown Greenville Lux Carriage House—Walk to Main St, SR Trail, The Well Arena
Downtown Greenville Lux Carriage House—Walk to Main St, SR Trail, The Well Arena
10.0 out of 10, Exceptional, (16)

Updated, Spacious 6br/4ba -Simpsonville
Updated, Spacious 6br/4ba -Simpsonville
10.0 out of 10, Exceptional, (1)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Upstate South Carolina

Mint House Greenville - Downtown
Mint House Greenville - Downtown
9.4 out of 10, Exceptional, (652)
The price is AED 493
AED 557 total
includes taxes & fees
4 May - 5 May

Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
10.0 out of 10, Exceptional, (4)
The price is AED 331
AED 505 total
includes taxes & fees
12 May - 13 May

Wooded Cottage - 3 Mi to Clemson University
Wooded Cottage - 3 Mi to Clemson University
10.0 out of 10, Exceptional, (1)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Upstate South Carolina hotels
Recent reviews of Upstate South Carolina hotels

Best Western Plus Greenville I-385 Inn & Suites
5/5 Excellent
"Cool"
A verified traveler stayed at Best Western Plus Greenville I-385 Inn & Suites
Posted 1 day ago
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