Search Vacation Homes in Upstate South Carolina

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Compare 937 Vacation Homes in Upstate South Carolina with updated reviews, rates, and availability.

Near great hiking trails and the friendly amenities of downtown Travelers Rest

9.8 out of 10, Exceptional, (40)
"Nice quiet neighborhood near the bike trail, and a clean and roomy house - just what I was looking for!"
Near great hiking trails and the friendly amenities of downtown Travelers Rest

Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson

10.0 out of 10, Exceptional, (79)
"We enjoyed our stay and the beautiful lake view. Nice home, but it needs some work. "
Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson

Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath

10.0 out of 10, Exceptional, (63)
"relaxing on porch"
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath

Beautiful Home Close To Everything

9.4 out of 10, Exceptional, (158)
"This house was very nice and clean. The beds were super comfortable. It is located not too far from downtown which was great. We definitely enjoyed our stay here. Communication with the property manager was very easy and timely. No complaints from our group. "
Beautiful Home Close To Everything

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

9.8 out of 10, Exceptional, (116)
"The house is wonderful with everything we needed for a great vacation, including lots of room for my grandsons, lots of space for us to enjoy meals on the deck and a fire pit for nightly s’mores. Debbie was responsive to all questions and we could not ask for a better host!"
The price is AED 1,451
AED 2,723 total
includes taxes & fees
11 May - 12 May
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Enjoy your stay in the West End of Greenville in our Mill Village House

10.0 out of 10, Exceptional, (9)
"Great"
Enjoy your stay in the West End of Greenville in our Mill Village House

New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville

9.8 out of 10, Exceptional, (47)
"Beautiful space, incredible kitchen, everything was very clean."
New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville

Great weekend getaway just a mile from downtown!

10.0 out of 10, Exceptional, (10)
"This property was great for us as we were working nearby! Clean and cozy!"
Great weekend getaway just a mile from downtown!

Clemson House 1 mile from University & Stadium!

9.4 out of 10, Exceptional, (14)
"Came to visit my daughter at Clemson for the weekend. The house was close to campus. Easy check in and out and perfect for what we needed. Would stay here again!"
The price is AED 661
AED 1,382 total
includes taxes & fees
5 May - 6 May
Clemson House 1 mile from University & Stadium!

Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.

10.0 out of 10, Exceptional, (17)
"Four College friends getting together and enjoy Clemson. Great location long walk to the stadium by very doable on a Game Day weekend. Communications with owner was very good, check in and check out was SUPER convenient. "
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.

Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room

10.0 out of 10, Exceptional, (104)
"Our family had a great time at Tigertown Lake Escape. The property is exactly as advertised, and offers even more than the photos and descriptions online. The home was very clean, especially for a property that is so obviously pet friendly. There was plenty of room for our family, and local friends who stopped by to hang out-both inside and out. The bedrooms were perfect for our needs. The bathrooms were very nice, and well supplied with plenty of linens. The kitchen had all of the...
Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room

North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE

10.0 out of 10, Exceptional, (104)
"This place was perfect for our long weekend Spring Break with our daughter and her friend. Plenty of space to spread out. The paddle boards and private dock were well used. We did a boat tour of Jocassee out of Devils Fork State Park which was less than 10 minutes away. We enjoyed the quiet, away from our usual city sounds. We would recommend this place for sure!"
North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE

Luxury 6,000+ sq ft Hideaway with Heated Pool, Spa, & Sauna - near Greenville

10.0 out of 10, Exceptional, (4)
"Our big group, ranging an age from 3 to 40 years old had an absolutely wonderful time at this house! The kitchen is well stocked"
The price is AED 1,120
AED 2,962 total
includes taxes & fees
5 May - 6 May
Luxury 6,000+ sq ft Hideaway with Heated Pool, Spa, & Sauna - near Greenville

Designer Retreat in Quaint Historic District w Front Porch Dining under the oaks

10.0 out of 10, Exceptional, (50)
"Everything was absolutely perfect! The Pettigru House had everything that we needed for our weekend visit to attend a family wedding. Gorgeous home with wonderful beds and showers. My family of adult children appreciate a good cup of coffee... or two.. and the coffee bar was on-point! My daughter and I appreciated the desk in the primary bedroom and the little stools and mirror in one of the other bedrooms. Those touches created a relaxing space for getting ready. You really thought of...
The price is AED 1,282
AED 2,424 total
includes taxes & fees
13 May - 14 May
Designer Retreat in Quaint Historic District w Front Porch Dining under the oaks

New Luxury Townhouse - Central to Downtown Greenville

10.0 out of 10, Exceptional, (47)
"Overall, we had a rejuvenating, perfect weekend in Greenville at this home. Owners were superb with communication and home is magazine ready and extremely cozy. Don't think twice, go ahead and book for your getaway. "
The price is AED 698
AED 1,434 total
includes taxes & fees
28 Apr - 29 Apr
New Luxury Townhouse - Central to Downtown Greenville

Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!

Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!

Beautiful home in the Heart of Five Forks, Simpsonville!

10.0 out of 10, Exceptional, (25)
"The property was very spacious in a nice quiet neighborhood. It worked well with our large group. The location was perfect too. It was close to all our adventures."
Beautiful home in the Heart of Five Forks, Simpsonville!

Keowee Key Condo w/ Lake Access & Community Pools!

2.0 star property
10.0 out of 10, Exceptional, (8)
"Good"
Keowee Key Condo w/ Lake Access & Community Pools!

Discover Your Vacation Haven in Greenville, SC – B5 Homes!

9.8 out of 10, Exceptional, (94)
"The house was perfect for a short getaway with my family. Loved the screened back porch."
Discover Your Vacation Haven in Greenville, SC – B5 Homes!

2 bedroom 2 bath near downtown greer !

10.0 out of 10, Exceptional, (39)
"We were visiting family near Greer and wanted a place close to town and near our family and we hit the jackpot! It was easy to book and Janet the host is very nice and made it easy to check in and out. This house is beautiful, very clean and is exactly as it’s described online. We definitely recommend staying there and it will be where we will stay on our next trip to the area!! "
The price is AED 459
AED 661 total
includes taxes & fees
30 Apr - 1 May
2 bedroom 2 bath near downtown greer !
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Upstate South Carolina

Mint House Greenville - Downtown

4.0 star property
9.4 out of 10, Exceptional, (652)
"Great value. Room was clean and nice. Would recommend to others. Location is great too. Only wish you could park in the lot by the hotel."
The price is AED 493
AED 557 total
includes taxes & fees
11 May - 12 May
Mint House Greenville - Downtown

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (4)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"
The price is AED 331
AED 505 total
includes taxes & fees
11 May - 12 May
Postcard Cabins Lake Hartwell

Wooded Cottage - 3 Mi to Clemson University

3.0 star property
10.0 out of 10, Exceptional, (1)
Wooded Cottage - 3 Mi to Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.