Search Vacation Homes in Upstate South Carolina

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Compare 758 Vacation Homes in Upstate South Carolina with updated reviews, rates, and availability.

Downtown Greer House Walkable to Shops, Restaurants, & Park. Fenced in Backyard.

9.2 out of 10, Wonderful, (97)
"The home was perfect for what we needed. It is very close to center Greer and it's amenities. Very close to all the restaurants and shopping you may want to do. The home itself is a quaint little bungalow that has all the accoutrements necessary for a long weekend stay. The backyard is of ample size and our pups enjoyed running around - it is not directly accessible from the house :( but the size is great. We really enjoyed our stay!!"
The price is AED 327
AED 776 total
includes taxes & fees
30 Dec - 31 Dec
Downtown Greer House Walkable to Shops, Restaurants, & Park. Fenced in Backyard.

Serene 4-bedroom house in Greenville with WiFi

2.0 out of 10, (1)
"We booked the stay and paid the agreed price. The evening before arriving, I rec'd several emails to inform me of an issue with VRBO (fake) and told to pay via apple pay the amount due or they would cancel the reservation. This went on for hours as I called VRBO and confirmed that they in fact were paid and told not to send any money. We then proceeded to cancel the reservation and had to pivot on where to stay. "
The price is AED 367
AED 925 total
includes taxes & fees
28 Dec - 29 Dec
Serene 4-bedroom house in Greenville with WiFi

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

9.8 out of 10, Exceptional, (130)
"We enjoyed our stay! The long table was perfect for a large group to eat and hang out. There was plenty of space for our large party. Instructions were great. Owner responded quickly when we thought we had a problem with one of the faucets. Turned out to be user error. Will be back. "
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Private, pet-friendly adorable getaway mins to downtown

9.8 out of 10, Exceptional, (78)
"Had some friends and family over and it was a great time. Nice backyard area with fire place "
The price is AED 551
AED 1,139 total
includes taxes & fees
3 Jan - 4 January 2025
Private, pet-friendly adorable getaway mins to downtown

New Luxury Townhouse - Central to Downtown Greenville

10.0 out of 10, Exceptional, (37)
"Very cool condo in a safe and quiet area of town. Close to downtown bars and restaurants. Fast and clear communication from our host. Highly recommend!"
The price is AED 735
AED 1,483 total
includes taxes & fees
16 Jan - 17 January 2025
New Luxury Townhouse - Central to Downtown Greenville

Charming 5 Bedroom Spacious Home 12 mins to Downtown Greenville

9.8 out of 10, Exceptional, (11)
"Wonderful, spacious, clean home! Perfect for a multi generational family stay! Easy driving distance to downtown Greenville! Excellent how communication! Definitely recomend!!"
Charming 5 Bedroom Spacious Home 12 mins to Downtown Greenville

Peaceful Retreat --- PERFECT LOCATION!!!

10.0 out of 10, Exceptional, (176)
"The house was immaculate. "
Peaceful Retreat --- PERFECT LOCATION!!!

GORGEOUS 2 BR on MAIN #4

9.8 out of 10, Exceptional, (27)
"Wonderfully convenient. Clean, comfortable and walking distance to everything! Very responsive and accommodating host. "
The price is AED 696
AED 1,251 total
includes taxes & fees
13 Jan - 14 January 2025
GORGEOUS 2 BR on MAIN #4

Boutique hotel in historic downtown Seneca. Room #6, King Bed.

9.6 out of 10, Exceptional, (17)
"Great room, very clean and comfortable bed!"
The price is AED 477
AED 769 total
includes taxes & fees
23 Dec - 24 Dec
Boutique hotel in historic downtown Seneca. Room #6, King Bed.

Peaceful Six Mile Vacation Home w/ Fire Pit

10.0 out of 10, Exceptional, (5)
"Great location, clean and quiet property, not a far drive to Big Rock for a day of climbing. Will definitely book again ."
Peaceful Six Mile Vacation Home w/ Fire Pit

The Burrow-cozy boutique studio walkable to downtown

10.0 out of 10, Exceptional, (53)
"Just had one night to enjoy this lovely appointed studio. Will definitely book again"
The Burrow-cozy boutique studio walkable to downtown

New! Boutique Tiny Home on the Saluda River

9.8 out of 10, Exceptional, (56)
"The property is fabulous. It's located just west of Greenville (a beautiful city) on the banks of the Saluda river. It is a privately-owned tiny home in a group of other homes in the Saluda Outdoor River Co (closed for the season). The ambience is perfect - string lights draped between trees, fire pits, outdoor seating areas and of course the view is fabulous. The home has everything you need - plus wine! Lots of thoughtful touches. "
New! Boutique Tiny Home on the Saluda River

Close To It All- Greenville, SC

9.0 out of 10, Wonderful, (2)
"House has been updated and is nice. Needs new sofa in living room and dryer doesn’t work properly. Nice hosts"
Close To It All- Greenville, SC

New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville

9.8 out of 10, Exceptional, (43)
"Came down to Greenville to check out the area for a possible move some day. Great town, so much to do. We will definitely be coming back. This place was in a great location and easily walkable to downtown. The condo was clean and very nice. "
New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville

Sanitized! Spacious Ranch Close To Gsp Airport, Greenville, Greer set on acres.

9.8 out of 10, Exceptional, (128)
"Large property with plenty of running room for my dog and toddler. Very clean inside with very comfortable accommodations. I would definitely rent again in the future!"
Sanitized! Spacious Ranch Close To Gsp Airport, Greenville, Greer set on acres.

STRATHAM STATION: 4Bd/2.5Ba in Downtown Greenville, SC

9.6 out of 10, Exceptional, (33)
"The property itself was nice, modern, and looked just as pictured. Though, there were no paper towels provided, typically we see 1-2 rolls provided in our stays. We did encounter some difficulties with communication with the host. They were not able to refer back to a chat we had over Vrbo prior to booking with questions we had. It was frustrating having to confirm this all again the day before checking in while coordinating with multiple people. The host ended up being accommodating...
The price is AED 694
AED 1,560 total
includes taxes & fees
9 Jan - 10 January 2025
STRATHAM STATION: 4Bd/2.5Ba in Downtown Greenville, SC

Shopping and Dining in Downtown Greenville! Swimming Pool, Pets Allowed!

9.0 out of 10, Wonderful, (4)
"The hotel was fine, good location "
The price is AED 613
AED 786 total
includes taxes & fees
24 Dec - 25 Dec
Shopping and Dining in Downtown Greenville! Swimming Pool, Pets Allowed!

Country escape with AC near Greenville, SC

2.0 star property
7.2 out of 10, Good, (5)
"The property was cute and the owner was friendly and messaged me back right away. However the first night the neighbors behind were pulling a trailer up and down the driveway from midnight to about 2am so it was very difficult to sleep. Overall it was a good experience. "
Country escape with AC near Greenville, SC

Valley Echoes on Lake Hartwell!

2.0 star property
10.0 out of 10, Exceptional, (1)
"We enjoyed our stay very much. The house was very clean and it had everything we needed. We enjoyed having breakfast on the dock. We would stay there again."
Valley Echoes on Lake Hartwell!

Spacious 8-bedroom house with WiFi and AC on peaceful Lake Keowee private cove.

10.0 out of 10, Exceptional, (2)
"Our family all got together at this house on Keowee Lake to celebrate Thanksgiving. The whole place was spotless when we arrived, and we were pleased to see how well stocked the kitchen was with pots and pans, and a variety of cooking utensils and electric appliances. Even though it was cool in November, we still enjoyed sitting out on the deck. We will certainly come back here again, although probably when the weather is a little warmer. The lake is beautiful, but in November, it was too cold...
Spacious 8-bedroom house with WiFi and AC on peaceful Lake Keowee private cove.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Upstate South Carolina

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (576)
"Great location!"
The price is AED 352
AED 398 total
includes taxes & fees
5 Jan - 6 January 2025
Mint House Greenville - Downtown

stayAPT Suites Greenville-Haywood Mall

3.0 star property
9.0 out of 10, Wonderful, (164)
"Very nice setting with friendly and helpful staff. The suite set-up was pleasant. More set up for long-term stays, with weekly housekeeping, though there were no drawers in the suite we stayed in."
The price is AED 400
AED 440 total
includes taxes & fees
31 Dec - 1 January 2025
stayAPT Suites Greenville-Haywood Mall

Mint House Greenville - West End

4.0 star property
9.2 out of 10, Wonderful, (71)
"Best place to stay in Greenville for a private condominium like setting in lieu of a hotel. We have stayed at this location multiple times and would recommend. "
The price is AED 487
AED 550 total
includes taxes & fees
2 Jan - 3 January 2025
Mint House Greenville - West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.