Search Vacation Homes in Upstate South Carolina

Plan, book, stay with confidence

Be picky

Search almost a million properties worldwide

Treat yourself

Change your mind

Book hotels with free cancellation

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Compare 758 Vacation Homes in Upstate South Carolina with updated reviews, rates, and availability.

"Came down to Greenville to check out the area for a possible move some day. Great town, so much to do. We will definitely be coming back. This place was in a great location and easily walkable to downtown. The condo was clean and very nice. "

"Very nice property. Comfortable, clean and quiet. A bit away from everything, but manageable. Would definitely stay again. "

"Loved the porch and location"

"Home was setup nicely and conveniently located."

"Owner communication was very good.Location is near anything you may need.Had a Christmas tree which was a nice surprise.Beds were good, but the furniture in rest of home needs an upgrade.New blinds needed on back slider door.Older neighborhood, but seemed safe."

AED 1,402 total

includes taxes & fees

27 Jan - 28 Jan

"If you're looking to get away and have a relaxing stay at the lake, this is your place. Ours was a winter stay so we took water activities off the table, but the setting is ideal and the house is so well appointed that even our teenagers enjoyed themselves. The kitchen was very well-equipped which is a major plus in remote locations. We found everything we needed to prepare meals. We also enjoyed making s'mores over the fire pit. We took a trip to visit the dam which we all enjoyed. Would...

"We stayed here for a quick 2-night family visit. When we arrived, we found the house to be very clean and comfortable. The location is very convenient to local restaurants and shopping. Overall, we really enjoyed our stay and hope to stay again the next time we’re in Greenville."

"Due to the timing after an unexpected death in our family, we had to add days in the front and back end of our original booking. Landon was very accommodating and understanding of our situation.The house is very clean, spacious and comfortable. We also appreciated the many extras that were available that you don't often find in other VRBOs such as spices, cooking oil, laundry and dish detergent, coffee etc.I gave 4 stars on location only because the home is on a main road and sometimes the cars...

AED 1,184 total

includes taxes & fees

27 Jan - 28 Jan

Six Mile Vacation Rental | 3BR | 2BA | 1,260 Sq Ft | Stairs Required

"Great location, clean and quiet property, not a far drive to Big Rock for a day of climbing. Will definitely book again ."

Pass through bar window- Can watch TV any game from the bar- Cable, Netflix

"Just had one night to enjoy this lovely appointed studio. Will definitely book again"

living room from back sliding doors to patio

"Wonderful home! "

"It was a great experience overall and very well kept!"

"If you are looking for an awesome place to gather with family and/or friends, look no further. We gathered to celebrate our grand daughter’s graduation from Clemson. It was the perfect spot. A great space with lots to do and plenty of room to spread out. The younger adults played ping pong and darts. The kitchen is fully equipped with everything you could possibly need with a gorgeous table to enjoy meals together. The views are breath taking from the living area. I personally loved several...

AED 5,745 total

includes taxes & fees

26 Jan - 27 Jan

"The home is exactly as described. Very cute. It was very quiet. I could see it being a little more rowdy in the summer due to the location right by the river and the other accommodations near by. The hosts were super responsive to our questions and concerns. They made fantastic restaurant recommendations. The home is simple with not a lot of bells and whistles, but just what we needed to unplug for the weekend. Thank you for sharing your spot. "

"The place was home away from home ! Could not have asked for a better place !"

"Very clean, well appointed cottage, with beautiful views! Communication with the host was excellent. Everything we needed for a long weekend getaway. We look forward to returning in the future for another stay!"

"We were in town for our son's wedding. This location is perfect if you are attending a wedding at Intwined Acres in Simpsonville. We had multiple generations staying at the house from age 14 to age 99! It comfortably accommodated everyone and we had lots of space. The one level bedrooms made it easy for our aged parents to move through the house without risk of falls. It was clean, the owners gave great communication, the neighborhood is quiet and safe, and the location is wonderful. Could not...

"Thank you for your place so my family and I could grieve together while we laid our mom to rest. It sure made it a little easier being together. "

View from our dock to towards the end of the cove

"Our son recently moved to Seneca. This was our first trip to visit him. This place was perfect for our family. There was an enough space to spread out and not be crowded. The dock and kayaks were enjoyed by our teen sons. The location was convenient and close to everything. We will definitely be staying here again. "

"The stay was great and the house was so clean and welcoming…best host I’ve dealt with yet!!! So kind and understanding!!! Thank you again!!! "

Save an average of 15% on thousands of hotels when you're signed in

Other property types in Upstate South Carolina

"Lovely 1 bedroom apartment in a great location. I was in town for medical reasons and only needed to park in the area in the evening. I was able to find free parking on the street easily between 6pm -9am. The only negative was the music noise from the Orange Theory Fitness gym below my 2nd floor apartment that started at 5am. "

AED 455 total

includes taxes & fees

26 Jan - 27 Jan