Find 4 Star Hotels in Upstate South Carolina, SC from AED 414

March 2025

SundayMondayTuesdayWednesdayThursdayFridaySaturday

April 2025

SundayMondayTuesdayWednesdayThursdayFridaySaturday

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Upstate South Carolina 4 Star Hotels

Tonight
29 Mar - 30 Mar
Tomorrow
30 Mar - 31 Mar
Next weekend
4 Apr - 6 Apr
In two weeks
11 Apr - 13 Apr

Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (517)
"Great location to campus with wonderful service. "
The price is AED 657
AED 730 total
includes taxes & fees
31 Mar - 1 Apr
The Shepherd Hotel Downtown Clemson
Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (316)
"Amazing hotel , great experience . Definitely will stay again and stay longer If we are ever in the area ! "
The price is AED 988
AED 1,087 total
includes taxes & fees
20 Apr - 21 Apr
Grand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville
Exterior

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1059)
"It lives up to its Landmark Hotel status."
The price is AED 559
AED 633 total
includes taxes & fees
6 Apr - 7 Apr
The Westin Poinsett Greenville
Mint House Greenville - Downtown
Apartment, 2 Bedrooms | Laptop workspace, iron/ironing board, free WiFi, bed sheets

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (629)
"Great stay. Great communication!"
The price is AED 414
AED 467 total
includes taxes & fees
13 Apr - 14 Apr
Mint House Greenville - Downtown
Greenville Marriott
Lobby sitting area

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (547)
"staff friendly"
The price is AED 433
AED 492 total
includes taxes & fees
18 Apr - 19 Apr
Greenville Marriott
Hotel Hartness
Interior entrance

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (484)
"It was wonderful. I really enjoy this hotel. The only negative is their charging stations over charge. It was $12 to change my HPEV for 2 hours. Typically changing stations charge a lot less. "
The price is AED 542
AED 720 total
includes taxes & fees
20 Apr - 21 Apr
Hotel Hartness
The Abernathy of Clemson
Flat-screen TV

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (497)
"It was a great stay!"
The price is AED 694
AED 771 total
includes taxes & fees
31 Mar - 1 Apr
The Abernathy of Clemson
Mint House Greenville - West End
Apartment, 1 Bedroom | Laptop workspace, blackout drapes, iron/ironing board, free WiFi

Mint House Greenville - West End

4.0 star property
9.2 out of 10, Wonderful, (83)
"Great facilities, great amenities "
The price is AED 520
AED 587 total
includes taxes & fees
30 Mar - 31 Mar
Mint House Greenville - West End
The Station by Compo Hotels
Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (5)
"perfect home away from home... I wish they had these everywhere! Wonderful cozy comfy place on Swamp Rabbit Trail - 10 minute walk to downtown Traveler's Rest, 15 minute drive to downtown GVL. Perfect spot!"
The price is AED 833
AED 1,219 total
includes taxes & fees
30 Mar - 31 Mar
The Station by Compo Hotels
Liberty Hall Bed and Breakfast
Front of property

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (57)
"Amazing stay. Everyone was accommodating. From check in to leaving was excellent. Not to forget the breakfast. My trip was a solo stay; however I plan to bring my husband with me on my next visit."
The price is AED 627
AED 696 total
includes taxes & fees
30 Mar - 31 Mar
Liberty Hall Bed and Breakfast
Hotel Domestique
Fountain

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (29)
"Beautiful hotel with a European feel and beautiful views. The hotel staff were great and really liked the communication before, during and after our visit! 10 out of 10! "
The price is AED 1,576
AED 1,733 total
includes taxes & fees
30 Mar - 31 Mar
Hotel Domestique
Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is AED 426
AED 1,635 total
includes taxes & fees
31 Mar - 1 Apr
Lake Hartwell Frank Howard Home Clemson
Belvedere
Family House, 4 Bedrooms, Patio, Courtyard View | Bathroom | Combined shower/tub, free toiletries, hair dryer, bidet

Belvedere

4.0 star property
8.0 out of 10, Very Good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere
Pendleton
Exterior

Pendleton

4.0 star property
Pendleton
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Greenville Marriott is rated highly by many Expedia guests. Located in Greer, Upstate South Carolina, this 4-star hotel features lots of amenities to help make your stay comfortable and convenient.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from AED 414

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.
Does Upstate South Carolina have any 4-star all-inclusive resorts?
Enjoy a relaxing vacation experience where just about everything is included in one upfront price by using our “All inclusive” filter. Staying within budget is a breeze when your room, food and many activities are already taken care of. Eager for more options? Check out the terrific offers on our standard 4-star hotels in and around Upstate South Carolina too.
Are there any 4-star hotels near Greenville-Spartanburg Intl. Airport (GSP)?
For those early departures or late-in-the-evening flights, Greenville Marriott is a great option. This 4-star retreat is about 8 kilometers from Greenville-Spartanburg Intl. Airport (GSP), one of the main airports in Upstate South Carolina.