Find 5 Star Hotels in St. Louis, MO from AED 382

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Check availability on St. Louis 5 Star Hotels

Tonight
23 Mar - 24 Mar
Tomorrow
24 Mar - 25 Mar
Next weekend
28 Mar - 30 Mar
In two weeks
4 Apr - 6 Apr

Compare St. Louis 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (526)
"good"
The price is AED 2,127
AED 2,477 total
includes taxes & fees
24 Mar - 25 Mar
The Ritz-Carlton, St. Louis
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (992)
"Beautiful and friendly. Loved it. "
The price is AED 1,469
AED 1,718 total
includes taxes & fees
30 Mar - 31 Mar
Four Seasons Hotel St Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Louis.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
The price is AED 386 per night from Apr 18 to Apr 19
AED 386
AED 455 total
includes taxes & fees
18 Apr - 19 Apr
8.4/10 Very Good! (3,604 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis and related destinations

Stroll under the Gateway Arch, explore a plethora of museums and enjoy an outstanding music scene initiated by natives Chuck Berry and Miles Davis.

See all hotels in St. Louis

With art galleries, farmers markets, jazz clubs, state-of-the-art sports stadiums, theaters and a zoo, there’s never a dull moment in this city, whose residents love barbecue and sports.

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Union Station featuring heritage architecture, landscape views and a high rise building

The capital of Ohio is known for its street food, cultural festivals and art scene. It’s also home to one of the largest state universities in the U.S.

See all hotels in Columbus
Columbus which includes a pond, a park and a city

The Steel City shimmers with natural beauty, architectural flair and cultural panache.

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Visit Ohio’s largest city for excellent museums, an expansive network of parks, passionate sporting events and the Cleveland Metroparks Zoo.

See all hotels in Cleveland

Frequently asked questions

What are the best 5-star hotels in St. Louis?
Boasting first-rate amenities and guest services, our customers rate Four Seasons Hotel St Louis as among the best 5-star hotels in St. Louis. You’ll be immersed in a world of luxury from the moment you step foot into the lobby.
How much does it cost to stay in a 5-star hotel in St. Louis?
There are a range of pricing options for 5-star hotels in St. Louis on Expedia. How much you’ll pay will depend on your vacation dates, trip length and other factors. Compare all of the available accommodations for your chosen dates and make use of our pricing and other filters to find the perfect luxury stay.

  • Search for the lowest price per night from AED 382

What makes a hotel 5 stars in St. Louis?
In St. Louis, a hotel needs to offer a certain number of upscale features to be rated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may also offer additional touches like welcome gifts.
Are there any 5-star all-inclusive resorts in St. Louis?
Find a luxury escape that includes your room, meals, drinks and entertainment in St. Louis with the help of Expedia’s filter tool. Search for hotels with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the upfront price. That way, you’re ready to take advantage of all the premium perks when you arrive.
What are the top 5-star spa hotels in St. Louis?
For a rejuvenating stay in St. Louis, it’s hard to beat Four Seasons Hotel St Louis. Book in to this 5-star spa getaway and spend your days pampering yourself with its well-being programs and therapies.
Are there any 5-star vacation rentals in St. Louis?
You won’t find any 5-star vacation rentals in St. Louis on our site, but there are a few other top-rated properties worth checking out. Browse our vacation rentals in St. Louis to discover the perfect place for your stay.
Are there any 5-star hotels in downtown St. Louis?
Spend your break at Four Seasons Hotel St Louis and enjoy being close to the lively action of downtown St. Louis.