Find 5 Star Hotels in St. Louis, MO from AED 340

Compare St. Louis 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (968)
"Wonderful stay! Thank you!"
The price is AED 1,377
AED 1,611 total
includes taxes & fees
4 Jan - 5 January 2025
Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (521)
"We like everything. This was our first trip to St Louis. The hotel and surroundings exceeded all our expectations. We booked 3 rooms and they got us all on the same floor. It was Christmas and the decorations and festivities were wonderful."
The price is AED 1,870
AED 2,178 total
includes taxes & fees
11 Jan - 12 January 2025
The Ritz-Carlton, St. Louis
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Frequently asked questions

What are the best 5-star hotels in St. Louis?
Boasting first-rate amenities and guest services, our customers rate Four Seasons Hotel St Louis as among the best 5-star hotels in St. Louis. You’ll be immersed in a world of luxury from the moment you step foot into the lobby.
How much does it cost to stay in a 5-star hotel in St. Louis?
There are a range of pricing options for 5-star hotels in St. Louis on Expedia. How much you’ll pay will depend on your vacation dates, trip length and other factors. Compare all of the available accommodations for your chosen dates and make use of our pricing and other filters to find the perfect luxury stay.

  • Search for the lowest price per night from AED 340

What makes a hotel 5 stars in St. Louis?
In St. Louis, a hotel needs to offer a certain number of upscale features to be rated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may also offer additional touches like welcome gifts.
Are there any 5-star all-inclusive resorts in St. Louis?
Find a luxury escape that includes your room, meals, drinks and entertainment in St. Louis with the help of Expedia’s filter tool. Search for hotels with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the upfront price. That way, you’re ready to take advantage of all the premium perks when you arrive.
What are the top 5-star spa hotels in St. Louis?
For a rejuvenating stay in St. Louis, it’s hard to beat Four Seasons Hotel St Louis. Book in to this 5-star spa getaway and spend your days pampering yourself with its well-being programs and therapies.
Are there any 5-star vacation rentals in St. Louis?
You won’t find any 5-star vacation rentals in St. Louis on our site, but there are a few other top-rated properties worth checking out. Browse our vacation rentals in St. Louis to discover the perfect place for your stay.
Are there any 5-star hotels in downtown St. Louis?
Spend your break at Four Seasons Hotel St Louis and enjoy being close to the lively action of downtown St. Louis.