Find Resorts & Hotels with Spas in Clayton, MO

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Check availability on Clayton Resorts & Hotels with Spas

Compare Clayton Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Outdoor dining

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3.0 star property
9.0 out of 10, Wonderful, (821)
"Overall good location. Clean with continental breakfast. Room was not ready during check in (arrived around 430p) but the desk was informative and kind. No other issues. Room was nice and comfortable. "
The price is AED 434
AED 510 total
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (524)
"We like everything. This was our first trip to St Louis. The hotel and surroundings exceeded all our expectations. We booked 3 rooms and they got us all on the same floor. It was Christmas and the decorations and festivities were wonderful."
The price is AED 2,126
AED 2,477 total
includes taxes & fees
14 Mar - 15 Mar
The Ritz-Carlton, St. Louis
Le Méridien St. Louis Clayton
Lounge

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (572)
"Location"
The price is AED 584
AED 686 total
includes taxes & fees
16 Mar - 17 Mar
Le Méridien St. Louis Clayton
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
9.0 out of 10, Wonderful, (3003)
"Great location "
The price is AED 366
AED 427 total
includes taxes & fees
6 Apr - 7 Apr
Clayton Plaza Hotel & Extended Stay
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property entrance

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (556)
"I had a very pleasant stay at the Seven Gables Inn. The room was big (213) and clean. Huge marble bath and heated toilet. Some of the hotel needs a paint job or renovation but the room was great. People friendly and made an extra effort. My colleague stayed in a different room half the size and was not happy so now I understand the mixed reviews on the site. Ask for room 213 or equivalent. "
The price is AED 477
AED 567 total
includes taxes & fees
30 Mar - 31 Mar
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Residence Inn By Marriott St. Louis Clayton
View from property

Residence Inn By Marriott St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (145)
"Hotel staff were amazing , loved the room very spacious definitely was able to relax and would book again "
The price is AED 606
AED 749 total
includes taxes & fees
30 Mar - 31 Mar
Residence Inn By Marriott St. Louis Clayton
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Property grounds

King Bed, Comfy Environment, Cozy Space, Corporate Luxury

9.4 out of 10, Exceptional, (3)
"We thoroughly enjoyed our stay. The rooftop views are tremendous!"
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Clayton?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Clayton. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Clayton?
Among Expedia’s 10 accommodation options in Clayton, there are 3 spa hotels.
What's there to see and do in Clayton?
Enjoy all that Clayton has to offer when you visit Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Union Station, and St. Louis Zoo. If you have some spare time during your trip, you might want to check out City Museum and Busch Stadium.
What is a Clayton spa hotel?
Spa hotels in Clayton provide lodging and have an on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.