Photo by Leonardo De Leon

Find hotels in Otay Mesa West, San Diego from AED 257

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Discover 6,570 Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1140)
"It was my first time coming here, and I will definitely come again!"
The price is AED 331
AED 408 total
includes taxes & fees
26 Mar - 27 Mar
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.8 out of 10, Good, (1007)
"Breakfast was very basic! "
The price is AED 328
AED 361 total
includes taxes & fees
31 Mar - 1 Apr
Days Inn by Wyndham San Diego-East/El Cajon

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1006)
"We reported damage to clothing from an iron which dropped rusty water on it. I was told the manager would ve in touch but never heard from him. "
The price is AED 423
AED 465 total
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (278)
"Thank you for making my trip better. it's the little things that matter to like having water there to drink, and when you are tired from your trip that they are ready for you to check in."
The price is AED 643
AED 708 total
includes taxes & fees
6 Apr - 7 Apr
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1123)
"Excellent property, great complimentary breakfast and very nice staff"
The price is AED 621
AED 685 total
includes taxes & fees
16 Apr - 17 Apr
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.4 out of 10, (1004)
"has a lot of bugs"
The price is AED 271
AED 299 total
includes taxes & fees
27 Mar - 28 Mar
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1073)
"Great little motel. Very clean and the location is great, especially if you’re visiting a student at sdsu. The only complaint is the water pressure. We were in room 106 and I think a baby’s pee would rinse you off faster. Otherwise a fantastic place. "
The price is AED 499
AED 552 total
includes taxes & fees
27 Mar - 28 Mar
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1356)
"👍"
The price is AED 403
AED 443 total
includes taxes & fees
6 Apr - 7 Apr
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

2.5 star property
8.6 out of 10, Excellent, (1122)
"Friendly staff and clean facilities. "
The price is AED 426
AED 469 total
includes taxes & fees
13 Apr - 14 Apr
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (940)
"Pretty nice , had no issues, easy check in and out "
The price is AED 257
AED 290 total
includes taxes & fees
26 Mar - 27 Mar
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1003)
"I like this place it is comfortable and clean."
The price is AED 301
AED 338 total
includes taxes & fees
2 Apr - 3 Apr
Valli Hi Motel

Chula Vista Inn

2.5 star property
6.4 out of 10, (1001)
"Convert "
The price is AED 314
AED 345 total
includes taxes & fees
31 Mar - 1 Apr
Chula Vista Inn

Quality Inn San Diego South - Chula Vista

2.5 star property
7.6 out of 10, Good, (892)
"It is quite"
The price is AED 281
AED 309 total
includes taxes & fees
13 Apr - 14 Apr
Quality Inn San Diego South - Chula Vista

Days Inn by Wyndham Chula Vista/San Diego

2.0 star property
6.2 out of 10, (886)
"Clean and friendly "
The price is AED 290
AED 320 total
includes taxes & fees
22 Apr - 23 Apr
Days Inn by Wyndham Chula Vista/San Diego

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1727)
"Nice place to stay my only issue was my door was jammed but everything else was fine"
The price is AED 262
AED 288 total
includes taxes & fees
26 Mar - 27 Mar
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1122)
"Great place."
The price is AED 396
AED 436 total
includes taxes & fees
7 Apr - 8 Apr
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1007)
"Good place"
The price is AED 294
AED 324 total
includes taxes & fees
26 Mar - 27 Mar
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1354)
"The room was nice, the tv was nice, the building is starting to show age which is surprising for a Holiday Inn and the cost per night. "
The price is AED 281
AED 310 total
includes taxes & fees
31 Mar - 1 Apr
SureStay Hotel by Best Western Chula Vista San Diego Bay

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (894)
"The Staff is outstanding and really professional and keeps you room clean. I would recommend this place because it's central locations."
The price is AED 314
AED 347 total
includes taxes & fees
20 Apr - 21 Apr
Berkshire Motor Hotel

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1858)
"Nice and clean"
The price is AED 360
AED 417 total
includes taxes & fees
26 Mar - 27 Mar
The Rambler Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighborhood that travelers like for its cathedral.

How many hotels can I expect to find in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodations in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.

Where can I learn more about changing or cancelling my trip to Otay Mesa West?

To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.

What is there to do around this San Diego neighborhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.