Photo by Leonardo De Leon

Find hotels in Otay Mesa West, San Diego from AED 264

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Check prices for these dates

Tonight
10 Apr - 11 Apr
Tomorrow
11 Apr - 12 Apr
This weekend
11 Apr - 13 Apr
Next weekend
18 Apr - 20 Apr

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Discover 6,539 Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort
3 outdoor pools, cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1167)
"It's a nice casino."
The price is AED 353
AED 432 total
includes taxes & fees
20 Apr - 21 Apr
Sycuan Casino Resort
Days Inn by Wyndham San Diego-East/El Cajon
Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1003)
"Clean and very friendly staff."
The price is AED 309
AED 341 total
includes taxes & fees
16 Apr - 17 Apr
Days Inn by Wyndham San Diego-East/El Cajon
Super 8 by Wyndham El Cajon/San Diego
Lobby

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.6 out of 10, Good, (1002)
"Good stay and good service "
The price is AED 294
AED 324 total
includes taxes & fees
14 Apr - 15 Apr
Super 8 by Wyndham El Cajon/San Diego
Best Western Plus La Mesa San Diego
Lobby

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1000)
"THE STAFF WAS OUTSTANDING! THE ROOM WAS PERFECT FOR OUR NEEDS!"
The price is AED 453
AED 498 total
includes taxes & fees
21 Apr - 22 Apr
Best Western Plus La Mesa San Diego
SpringHill Suites by Marriott Chula Vista Eastlake
Suite, 1 King Bed, Patio, Poolside | View from room

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (298)
"Very accommodating and especially cleanliness. Easy check ins . Breakfasts just end too early!"
The price is AED 643
AED 708 total
includes taxes & fees
18 Apr - 19 Apr
SpringHill Suites by Marriott Chula Vista Eastlake
Ayres Hotel San Diego South - Chula Vista
Lobby lounge

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1103)
"Second time staying here. Staff is very friendly and helpful."
The price is AED 585
AED 645 total
includes taxes & fees
20 Apr - 21 Apr
Ayres Hotel San Diego South - Chula Vista
Heritage Inn La Mesa
Exterior

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1010)
"Room was clean and ready "
The price is AED 281
AED 310 total
includes taxes & fees
13 Apr - 14 Apr
Heritage Inn La Mesa
Lamplighter Inn & Suites at SDSU
Outdoor pool, pool umbrellas, sun loungers

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1094)
"very safe and clean"
The price is AED 530
AED 586 total
includes taxes & fees
14 Apr - 15 Apr
Lamplighter Inn & Suites at SDSU
Best Western Chula Vista/Otay Valley Hotel
Lobby

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1377)
"Everyone was so attentive loves it "
The price is AED 403
AED 443 total
includes taxes & fees
21 Apr - 22 Apr
Best Western Chula Vista/Otay Valley Hotel
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1138)
"Nice and clean "
The price is AED 437
AED 481 total
includes taxes & fees
13 Apr - 14 Apr
La Quinta Inn by Wyndham San Diego Chula Vista
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Desk, blackout drapes, iron/ironing board, free WiFi

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (965)
"Cercano a las outles, zona tranquila "
The price is AED 305
AED 344 total
includes taxes & fees
13 Apr - 14 Apr
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Valli Hi Motel
Desk, blackout drapes, soundproofing, free WiFi

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1000)
"Good place to stay. Clean, quiet, the staff are very nice and helpful. "
The price is AED 317
AED 357 total
includes taxes & fees
14 Apr - 15 Apr
Valli Hi Motel
Best Western Americana Inn
Pillowtop beds, in-room safe, desk, laptop workspace

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1068)
"Ok. Good"
The price is AED 449
AED 505 total
includes taxes & fees
16 Apr - 17 Apr
Best Western Americana Inn
Chula Vista Inn
Exterior

Chula Vista Inn

2.5 star property
6.4 out of 10, (1004)
"So quite "
The price is AED 314
AED 345 total
includes taxes & fees
13 Apr - 14 Apr
Chula Vista Inn
Quality Inn San Diego South - Chula Vista
Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Quality Inn San Diego South - Chula Vista

2.5 star property
7.6 out of 10, Good, (908)
"Better than most "
The price is AED 311
AED 342 total
includes taxes & fees
21 Apr - 22 Apr
Quality Inn San Diego South - Chula Vista
Hotel Palmeras Chula Vista
Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1722)
"Nice "
The price is AED 264
AED 291 total
includes taxes & fees
13 Apr - 14 Apr
Hotel Palmeras Chula Vista
Hercor Hotel - Urban Boutique
Deluxe Room, 1 King Bed | Premium bedding, down comforters, pillowtop beds, in-room safe

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1145)
"IMME HE QUEDADO EN ESTE HOTEL ANTES Y TODO ESTA MUY BIEN. LAS PERSONAS MUY AMABLES Y LOS CUARTOS MUY ESPACIOSOS"
The price is AED 396
AED 436 total
includes taxes & fees
23 Apr - 24 Apr
Hercor Hotel - Urban Boutique
Howard Johnson by Wyndham National City/San Diego South
Blackout drapes, iron/ironing board, free cribs/infant beds, free WiFi

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1004)
"Awesome"
The price is AED 316
AED 348 total
includes taxes & fees
13 Apr - 14 Apr
Howard Johnson by Wyndham National City/San Diego South
SureStay Hotel by Best Western Chula Vista San Diego Bay
Outdoor pool

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1373)
"Rooms are nice "
The price is AED 314
AED 346 total
includes taxes & fees
16 Apr - 17 Apr
SureStay Hotel by Best Western Chula Vista San Diego Bay
Berkshire Motor Hotel
Suite | Private kitchenette

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (903)
"I've enjoyed my stay for the last 3 weeks, housekeeping is amazing. They keep it really clean and their fun to talk to. "
The price is AED 363
AED 401 total
includes taxes & fees
29 Apr - 30 Apr
Berkshire Motor Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighborhood that travelers like for its cathedral.

How many hotels can I expect to find in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodations in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.

Where can I learn more about changing or cancelling my trip to Otay Mesa West?

To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.

What is there to do around this San Diego neighborhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.