Photo by Leonardo De Leon

Find 5 Star Hotels in Otay Mesa West, CA from AED 559

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Otay Mesa West 5 Star Hotels

Tonight
26 Apr - 27 Apr
Tomorrow
27 Apr - 28 Apr
Next weekend
2 May - 4 May
In two weeks
9 May - 11 May

Compare Otay Mesa West 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Pendry San Diego
Interior

Pendry San Diego

5.0 star property
9.2 out of 10, Wonderful, (1001)
"Amazing experience 😃❤️"
The price is AED 1,010
AED 1,358 total
includes taxes & fees
11 May - 12 May
Pendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego
View from property

The US Grant, a Luxury Collection Hotel, San Diego

5.0 star property
9.0 out of 10, Wonderful, (1003)
"• customer service - 5/5 - best customer service we’ve had from any hotel / resort • property - 5/5 - such a classy aesthetically pleasing hotel - I do wish there was a rooftop area or some sort of outdoor area • hotel room - 3/5 - we loved our hotel room - lots of pillows, comfy bed, the design & layout was beautiful & the bathroom was really nice - the only thing was that the air was a bit stuffy so we had to turn the a/c off & open the window for fresh air throughout the night. •...
The price is AED 1,008
AED 1,169 total
includes taxes & fees
11 May - 12 May
The US Grant, a Luxury Collection Hotel, San Diego
Beach Village at The Del, LXR Hotels & Resorts
Oceanfront Horizon Cottage | Living area | 42-inch LCD TV with cable channels, TV, fireplace

Beach Village at The Del, LXR Hotels & Resorts

5.0 star property
9.0 out of 10, Wonderful, (99)
"Would stay again "
The price is AED 2,909
AED 3,389 total
includes taxes & fees
12 May - 13 May
Beach Village at The Del, LXR Hotels & Resorts
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Otay Mesa West.
Wyndham San Diego Bayside

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego, CA
The price is AED 559 per night from May 11 to May 12
AED 559
AED 648 total
includes taxes & fees
11 May - 12 May
8.2/10 Very Good! (5,675 reviews)
Still don't see what you're looking for?
See all properties in Otay Mesa West.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.