Find Resorts & Hotels with Spas in Mission District, CA

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Check availability on Mission District Resorts & Hotels with Spas

Tonight
4 May - 5 May
Tomorrow
5 May - 6 May
Next weekend
9 May - 11 May
In two weeks
16 May - 18 May

Compare Mission District Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Inn San Francisco
Outdoor spa tub

Inn San Francisco

2.5 star property
9.6 out of 10, Exceptional, (520)
"Breakfast"
The price is AED 873
AED 1,015 total
includes taxes & fees
5 May - 6 May
Inn San Francisco
Noe's Nest Bed and Breakfast
Interior

Noe's Nest Bed and Breakfast

3.5 star property
9.4 out of 10, Exceptional, (108)
"Very charming B&B, with a colorful and delightful proprietor at the helm, supported by capable and friendly staff. Great location. Very nice neighborhood. Would definitely stay here again on my return to SFO. "
The price is AED 863
AED 1,004 total
includes taxes & fees
7 May - 8 May
Noe's Nest Bed and Breakfast
Union Hotel
View from property

Union Hotel

2.0 star property
7.0 out of 10, Good, (267)
"Enjoyed my stay at the property Very centered to several areas in SF Very convenient and suitable for my stay"
The price is AED 198
AED 231 total
includes taxes & fees
5 May - 6 May
Union Hotel
Parker Guest House San Francisco
Exterior

Parker Guest House San Francisco

3.5 star property
9.6 out of 10, Exceptional, (410)
"Friendly and engaging staff."
The price is AED 804
AED 937 total
includes taxes & fees
5 May - 6 May
Parker Guest House San Francisco
Charming 1 bed 1bath - 1 block to Dolores Park
Fridge, microwave, oven, stovetop

Charming 1 bed 1bath - 1 block to Dolores Park

Charming 1 bed 1bath - 1 block to Dolores Park
Quiet One Bedroom Suite in The Mission near Castro
Outdoor dining

Quiet One Bedroom Suite in The Mission near Castro

10.0 out of 10, Exceptional, (2)
"Apartment matches description. Due to basement location there isn’t much daylight but we were out and about during day. It’s cozy and comfortable and pretty quiet."
Quiet One Bedroom Suite in The Mission near Castro
Sunny Mission Studio 60 days minimum stay
Fridge, oven, stovetop

Sunny Mission Studio 60 days minimum stay

Sunny Mission Studio 60 days minimum stay
Colorful Mission District! Amazing Location! Comfortable Private Garden In-Law
Terrace/patio

Colorful Mission District! Amazing Location! Comfortable Private Garden In-Law

10.0 out of 10, Exceptional, (47)
"I stayed here for a month for a medical procedure that required I stay in the area for a month. Great location for necessities and dining options, the garden area is welcoming I regret not spending more time in it"
Colorful Mission District! Amazing Location! Comfortable Private Garden In-Law
Amazing Roof Deck in the Mission! Walk to Tartine Manufacture
Outdoor dining

Amazing Roof Deck in the Mission! Walk to Tartine Manufacture

9.6 out of 10, Exceptional, (15)
"Lots of room to entertain. The apartment furnishing need a little help. Kitchen was well stocked with cookware etc. We used the upper deck a lot but cushions were lacking. Plants and planters were in disrepair. However we would love to stay here again. The sunny Mission was true to its name. We walked everywhere with no problem. Didn’t walk past 17th, 16th st etc.on purpose. Having lived in SF in the 70’s it’s not the same city, homeless everywhere, garbage etc all over the streets and...
Amazing Roof Deck in the Mission! Walk to Tartine Manufacture
Best Mission Location - 100 Walk Score
Aerial view

Best Mission Location - 100 Walk Score

Best Mission Location - 100 Walk Score
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Mission District?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the art galleries and bars in Mission District—your day trip starts here. Be sure to pay a visit to the museums during your stay. Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels are there in Mission District?
Among Expedia’s 95 accommodation options in Mission District, there are 2 spa hotels.
What's there to see and do in Mission District?
Experience Mission District with a stop at San Francisco Public Library, Mission San Francisco de Asís, and SOMA Pilipinas. If you have a little extra time during your trip, you might want to make a stop at Hua Zang Si and Paxton Gate.
What is a Mission District spa hotel?
Spa hotels in Mission District provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.