Photo by Amber Palmer

Find hotels near Mayo Clinic Florida, Jacksonville from AED 404

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Compare 1,819 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (327)
"Great hotel to stay in with our pooch. Located off the I-95 but within the Mayo Clinic campus so got pass-through travelers as well as people going to the clinic. Very nice spot. "
The price is AED 643
AED 730 total
includes taxes & fees
9 Feb - 10 Feb
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

TownePlace Suites by Marriott Jacksonville East

2.5 star property
9.2 out of 10, Wonderful, (396)
"Great place"
The price is AED 444
AED 504 total
includes taxes & fees
9 Feb - 10 Feb
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Great stay, will come back!"
The price is AED 475
AED 539 total
includes taxes & fees
2 Feb - 3 Feb
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
8.4 out of 10, Very Good, (692)
"convenient to mayo clinic"
The price is AED 657
AED 746 total
includes taxes & fees
7 Feb - 8 Feb
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IHG Hotel

2.5 star property
8.2 out of 10, Very Good, (1011)
"Hotel was a good price. Very close to Mayo. We stayed for three days. Room was clean. Bathroom was a little older looking but not dirty. Overall good stay, and good price. "
The price is AED 470
AED 533 total
includes taxes & fees
26 Jan - 27 Jan
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IHG Hotel

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (272)
"Very good all around. "
The price is AED 517
AED 587 total
includes taxes & fees
28 Jan - 29 Jan
Salt Air Inn & Suites

Element Jacksonville Beach

3.0 star property
9.6 out of 10, Exceptional, (444)
"Amazing hotel. Clean rooms and amenities. Awesome breakfast. Will be back. "
The price is AED 404
AED 459 total
includes taxes & fees
9 Feb - 10 Feb
Element Jacksonville Beach

Holiday Inn Express & Suites Jacksonville - Town Center, an IHG Hotel

2.5 star property
9.6 out of 10, Exceptional, (1003)
"The property was clean and modern. Breakfast was good. Staff was very friendly and professional "
The price is AED 492
AED 559 total
includes taxes & fees
26 Jan - 27 Jan
Holiday Inn Express & Suites Jacksonville - Town Center, an IHG Hotel

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (278)
"The artwork in our room was very cool. "
The price is AED 657
AED 746 total
includes taxes & fees
26 Jan - 27 Jan
The Hotel Palms

AC Hotel Jacksonville St Johns Town Center

2.5 star property
9.6 out of 10, Exceptional, (73)
"Great experience !! Recommend highly :))"
The price is AED 657
AED 746 total
includes taxes & fees
26 Jan - 27 Jan
AC Hotel Jacksonville St Johns Town Center

Holiday Inn Express Jacksonville Beach, an IHG Hotel

2.5 star property
9.2 out of 10, Wonderful, (1002)
"It is a nice hotel but if you are sensitive to smell the cleaning supplies they use has strong fragrance in it."
The price is AED 448
AED 509 total
includes taxes & fees
9 Feb - 10 Feb
Holiday Inn Express Jacksonville Beach, an IHG Hotel

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (1993)
"From check in to check out I have no complaints. This is not my first time staying here and it won't be my last. Friendly staff, great rooms, beautiful view and beach access!!"
The price is AED 549
AED 623 total
includes taxes & fees
23 Jan - 24 Jan
Hampton Inn Jacksonville Beach/Oceanfront

Seahorse Oceanfront Inn

2.5 star property
9.2 out of 10, Wonderful, (381)
"This is such a beautiful place; especially if you like small business owned places. I love the character and the area is amazing. The beach is clean and so accessible."
The price is AED 447
AED 507 total
includes taxes & fees
27 Jan - 28 Jan
Seahorse Oceanfront Inn

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
9.2 out of 10, Wonderful, (1010)
"Staff were very helpful and pleasant. Great location. Many options to dine and walkable"
The price is AED 375
AED 425 total
includes taxes & fees
9 Feb - 10 Feb
Hyatt Place Jacksonville / St. Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center

2.5 star property
9.2 out of 10, Wonderful, (672)
"Clean basic comfortable rooms with fridge. Breakfast was simple but had everything you would need and was good. I would stay again. "
The price is AED 480
AED 545 total
includes taxes & fees
9 Feb - 10 Feb
Tru By Hilton Jacksonville St Johns Town Center

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
9.0 out of 10, Wonderful, (1000)
"Extremely good experience "
The price is AED 716
AED 813 total
includes taxes & fees
9 Feb - 10 Feb
Four Points by Sheraton Jacksonville Beachfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
9.0 out of 10, Wonderful, (389)
"The breakfast was awesome. Close to the beach. The pool was closed.for 1 week but that is understandable maintaining a pool has to be done. But so close to the beach the pool wasn't a big deal"
The price is AED 584
AED 663 total
includes taxes & fees
9 Feb - 10 Feb
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Margaritaville Jacksonville Beach

2.5 star property
9.0 out of 10, Wonderful, (2767)
"it was a woudful 2-nights stay. you can easily find a few nice seafood restaurants around (eg. north beach fish camp! i like it so much :))"
The price is AED 566
AED 642 total
includes taxes & fees
22 Jan - 23 Jan
Margaritaville Jacksonville Beach

Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel

3.5 star property
9.2 out of 10, Wonderful, (1006)
"I love Hotel Indigo! Every hotel feels unique and different. The staff are always helpful and friendly and the rooms are clean, funky, well apportioned and generous. This location is attached to a nice little shopping area on a lake. Had a lovely view and a bathroom that was large. Clean, generous, comfy bed …I’ll take all of it!"
The price is AED 441
AED 500 total
includes taxes & fees
1 Feb - 2 Feb
Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel

Hampton Inn & Suites Jacksonville Deerwood Park

2.5 star property
9.2 out of 10, Wonderful, (1002)
"All was in very good condition, the staff was absolutely amazing. Kelsey was the best."
The price is AED 379
AED 430 total
includes taxes & fees
2 Feb - 3 Feb
Hampton Inn & Suites Jacksonville Deerwood Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 33 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 33 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the natural beauty of Oceanfront Park, South Beach Park and Sunshine Playground, and Huguenot Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.