Find Luxury Hotels in Downtown Santiago

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Pick from 10 Downtown Santiago Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

The Singular Santiago
Front of property
The Singular Santiago
5.0 star property
9.4 out of 10, Exceptional, (515)
"The Singular exceeded our expectations, it was a wonderful hotel with a great location. Food and view from the rooftop bar was great! Staff was extremely friendly and very helpful, arranged a 4am transfer to the airport for us and packed us breakfast to go. "
The price is AED 1,451
AED 1,451 total
includes taxes & fees
7 Nov - 8 Nov
The Singular Santiago
Casa Bueras Boutique Hotel
Garden
Casa Bueras Boutique Hotel
4.5 star property
9.2 out of 10, Wonderful, (439)
"Excellent hotel"
The price is AED 562
AED 562 total
includes taxes & fees
1 Dec - 2 Dec
Casa Bueras Boutique Hotel
Luciano K Hotel
Pool
Luciano K Hotel
4.5 star property
9.0 out of 10, Wonderful, (519)
"The property is beautiful with interesting architecture and design choices everywhere. The rooftop bar and restaraunt is perfect after a day exploring the city!"
The price is AED 489
AED 489 total
includes taxes & fees
4 Dec - 5 Dec
Luciano K Hotel
Altiplanico Bellas Artes
Exterior
Altiplanico Bellas Artes
3.5 star property
9.2 out of 10, Wonderful, (482)
"Excelente atención "
The price is AED 514
AED 514 total
includes taxes & fees
6 Nov - 7 Nov
Altiplanico Bellas Artes
Matildas Hotel Boutique
Terrace/patio
Matildas Hotel Boutique
3.5 star property
9.2 out of 10, Wonderful, (236)
"Outstanding staff and charming and elegant building. Hotel was previously a mansion owned by a family member of a former President. Rooms are spacious. Breakfast is a delight. Stayed here on two separate occasions in September 2024 and all staff during those periods were helpful, attentive and a joy to meet."
The price is AED 476
AED 476 total
includes taxes & fees
17 Nov - 18 Nov
Matildas Hotel Boutique
Hotel Plaza San Francisco
Property entrance
Hotel Plaza San Francisco
4.0 star property
9.0 out of 10, Wonderful, (792)
"The staff were very friendly and accommodating. The food in the restaurant and bar was very good. The room and bed were very comfortable so it was an all-round enjoyable stay. "
The price is AED 516
AED 516 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Plaza San Francisco
Lastarria Hotel & Aparts
Front of property
Lastarria Hotel & Aparts
3.0 star property
9.0 out of 10, Wonderful, (224)
"The apartment we stayed in was beautiful and had all the amenities we needed! We particularly liked the layout of the apartment and how kind the staff were. They went the extra mile to help us understand the area as we are not fluent in the local language"
The price is AED 292
AED 292 total
includes taxes & fees
14 Nov - 15 Nov
Lastarria Hotel & Aparts
Hotel Vegas
View from property
Hotel Vegas
3.0 star property
8.0 out of 10, Very Good, (187)
"This was a wonderful little boutique hotel on a walkable cobbled street. The staff was exceptional and the room was very comfortable and quiet. It was easily in walking distance to Centro and right by a subway stop. Wonderful little place to stay. Thank you!"
Hotel Vegas
Rukaza Lastarria
Exterior
Rukaza Lastarria
3.0 star property
8.4 out of 10, Very Good, (46)
"Great location with commodities aroynd, close to downtown and subway. I extented my stay. :)"
Rukaza Lastarria
Hotel Panamericano
Room
Hotel Panamericano
3.0 star property
8.2 out of 10, Very Good, (141)
"Near everything walking distance "
The price is AED 421
AED 421 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Panamericano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Downtown Santiago?
During your visit, you might want to enjoy the museums and cathedral which Downtown Santiago is known for.
What's the best luxury accommodation in Downtown Santiago?
Luciano K Hotel is a luxury hotel with 2 restaurants and a full-service spa, and it’s a popular choice for Expedia travelers looking for an elegant place to stay. The Singular Santiago and Casa Bueras Boutique Hotel are other upscale choices for your stay.
How many luxury hotels should I expect to find in Downtown Santiago?
Lie in the lap of luxury during your getaway to Downtown Santiago in one of Expedia’s 12 luxury hotels.
What's the best time to vacation in Downtown Santiago?
The hottest months are usually January and February with an average temperature of 67°F,
  • Coldest months: July, June, August, and September
  • Driest months: March, February, January, and December
  • Rainiest months: June, August, July, and September
What's there to see and do in Downtown Santiago?
Experience Downtown Santiago with a stop at Fantasilandia, Palacio de la Moneda, and O’Higgins Park. If you have a little extra time during your trip, you might want to check out Movistar Arena and Parque Bicentenario.
How can I get around Downtown Santiago?
It’s easier to get around town comfortably when you know your options. You can take advantage of metro transit at Toesca Station, O’Higgins Park Station, and Heroes Station.