Find 4 Star Hotels in Clayton, MO from AED 338

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Compare Clayton 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt Regency St. Louis at The Arch
Exterior

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (3539)
"This hotel was amazing! Not only did we have the best view of the arch from our room but we were so impressed with how pet friendly the entire property was! A beautiful little park right outside the front entrance so we could easily walk our dogs and be near the arch for our sightseeing pleasure! We will definitely be back."
The price is AED 364
AED 429 total
includes taxes & fees
26 Dec - 27 Dec
Hyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel
Exterior

Renaissance St. Louis Airport Hotel

4.0 star property
8.2 out of 10, Very Good, (1002)
"Clean and resourceful "
The price is AED 419
AED 490 total
includes taxes & fees
24 Jan - 25 January 2025
Renaissance St. Louis Airport Hotel
21C Museum Hotel St Louis
Room

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (861)
"Absolutely beautiful hotel. Great staff too!"
The price is AED 490
AED 592 total
includes taxes & fees
26 Dec - 27 Dec
21C Museum Hotel St Louis
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1615)
"Beautiful hotel and a lot of space history. I enjoyed it from the moment I walked in. "
The price is AED 527
AED 627 total
includes taxes & fees
29 Dec - 30 Dec
Moonrise Hotel
Ameristar Casino Resort and Spa
Exterior

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1001)
"Really enjoyed the stay ALL was great, the slots were tight though.......never won and we definitely tried. Need more $5 minimum tables, rediculous. Use your brains marketing people 😜"
The price is AED 621
AED 787 total
includes taxes & fees
26 Dec - 27 Dec
Ameristar Casino Resort and Spa
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Exterior

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
8.6 out of 10, Excellent, (1001)
"Amazing stay. From the front desk to the room To valet. Would recommend to everyone. "
The price is AED 338
AED 395 total
includes taxes & fees
27 Dec - 28 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
The Last Hotel
Exterior

The Last Hotel

4.5 star property
7.8 out of 10, Good, (1161)
"Property was stunning! Staff was super friendly and we enjoyed our stay☺️"
The price is AED 410
AED 480 total
includes taxes & fees
26 Dec - 27 Dec
The Last Hotel
River City Casino & Hotel
Property entrance

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1005)
"Room was super nice and quiet. Bed was great! Cleaning staff did an excellent job and very accommodating when asked for extra towels. Check in staff were fantastic! Would definitely stay there again."
The price is AED 359
AED 459 total
includes taxes & fees
2 Jan - 3 January 2025
River City Casino & Hotel
Live by Loews - St.Louis
Exterior

Live by Loews - St.Louis

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Thank for everything‼️"
The price is AED 533
AED 633 total
includes taxes & fees
26 Dec - 27 Dec
Live by Loews - St.Louis
Le Méridien St. Louis Clayton
Room

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (546)
"Clean, very friendly staff. Very nice rooms! "
The price is AED 584
AED 686 total
includes taxes & fees
28 Dec - 29 Dec
Le Méridien St. Louis Clayton
St. Louis Union Station Hotel, Curio Collection by Hilton
Exterior

St. Louis Union Station Hotel, Curio Collection by Hilton

4.0 star property
8.2 out of 10, Very Good, (1002)
"I love the fact that everyone treats you with respect "
The price is AED 590
AED 702 total
includes taxes & fees
12 Jan - 13 January 2025
St. Louis Union Station Hotel, Curio Collection by Hilton
Hilton Pennywell St. Louis at the Arch
Exterior

Hilton Pennywell St. Louis at the Arch

4.0 star property
8.8 out of 10, Excellent, (637)
"Nice Hotel"
The price is AED 379
AED 447 total
includes taxes & fees
5 Jan - 6 January 2025
Hilton Pennywell St. Louis at the Arch
DoubleTree by Hilton St. Louis Forest Park
Exterior

DoubleTree by Hilton St. Louis Forest Park

4.0 star property
8.2 out of 10, Very Good, (1000)
"We have stayed at this hotel many times in the last 10 years because of the closeness and convenience to BJH. It’s always clean and comfortable. I really miss the days when it wasn’t operated by Hilton, however, because there were no added charges for parking or breakfast. Coffee, juice, popcorn and fruit were available always in the lobby. They always before offered a discount for patients of the hospital, also. Still, I give them a good review for cleanliness, comfort and quietness. "
The price is AED 514
AED 607 total
includes taxes & fees
27 Dec - 28 Dec
DoubleTree by Hilton St. Louis Forest Park
Embassy Suites by Hilton St. Louis Downtown
Living area

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
8.6 out of 10, Excellent, (1071)
"Staff was super helpful and friendly. Valet was awesome. Pool areas only 3 ft and didn’t seem to be heated (it’s also December so how hot can they get if you know). I had to get 4 different key cards because they would stop working but it’s not their fault. Something to do with the magnets and our phones. We did get a noise complaint from the neighbors at 10 o’clock on a Friday night lol. Staff was super nice about it tho. The staff really went above and beyond which was awesome. I had a great...
The price is AED 398
AED 474 total
includes taxes & fees
1 Jan - 2 January 2025
Embassy Suites by Hilton St. Louis Downtown
The Cheshire
Outdoor pool

The Cheshire

4.0 star property
8.4 out of 10, Very Good, (1003)
"Exactly what I read it to be"
The price is AED 473
AED 562 total
includes taxes & fees
30 Dec - 31 Dec
The Cheshire
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Exterior

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4.0 star property
8.6 out of 10, Excellent, (1000)
"Get workout facilities "
The price is AED 434
AED 503 total
includes taxes & fees
17 Jan - 18 January 2025
DoubleTree by Hilton Hotel St. Louis - Chesterfield
The Westin St. Louis
Exterior

The Westin St. Louis

4.5 star property
8.4 out of 10, Very Good, (1002)
"Everything was great - very easily walkable to much of what St. Louis has to offer. Several parking options as well. Will be back! "
The price is AED 403
AED 471 total
includes taxes & fees
10 Jan - 11 January 2025
The Westin St. Louis
Marriott St. Louis Airport
Exterior

Marriott St. Louis Airport

4.0 star property
7.8 out of 10, Good, (1003)
"Some key areas were a little dirty, gym was very neglected. The room had some hard to miss stains on mirrors and walls. But i can see rushed cleaning because of a huge event causing some issues."
The price is AED 470
AED 561 total
includes taxes & fees
10 Jan - 11 January 2025
Marriott St. Louis Airport
The Royal Sonesta Chase Park Plaza St. Louis
Lobby

The Royal Sonesta Chase Park Plaza St. Louis

4.5 star property
9.0 out of 10, Wonderful, (1001)
"Being close to the park is great. Will come back in the summer"
The price is AED 691
AED 923 total
includes taxes & fees
2 Jan - 3 January 2025
The Royal Sonesta Chase Park Plaza St. Louis
Marriott St. Louis Grand
Exterior

Marriott St. Louis Grand

4.0 star property
8.0 out of 10, Very Good, (1002)
"Clean, super accessible to the done and downtown! Highly recommended!!"
The price is AED 496
AED 590 total
includes taxes & fees
1 Jan - 2 January 2025
Marriott St. Louis Grand
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO
The price is AED 1,377 per night from Jan 11 to Jan 12
AED 1,377
AED 1,611 total
includes taxes & fees
11 Jan - 12 January 2025
9.4/10 Exceptional! (970 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Clayton?
Kick back and unwind in 4-star hotel comfort at Le Méridien St. Louis Clayton. Rated highly by many of our guests, it offers concierge services and premium bedding. Also check out The Cheshire. Egyptian-cotton sheets and a terrace help make this escape another popular choice in Clayton.
How much does it cost to stay in a 4-star hotel in Clayton?
With Expedia’s search and sort filters, locking in a superb deal on a 4-star hotel in Clayton just got easier. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best fits your style and budget.

  • Search for the lowest price from AED 1,377

What's the difference between 5-star and 4-star hotels in Clayton?
If you choose to vacation at a 4-star hotel in Clayton, you’ll usually find loads of conveniences to ensure you’re comfortable, such as a restaurant, pool and gym. You can look forward to high-quality service and upscale surroundings. Go for a 5-star hotel and you’ll get a few extra bells and whistles — think on-site spas, 24-hour front desk and opulent turndown services. You’re likely to get extra amenities and premium services at a 5-star retreat, but both are awesome options for luxury guests.
Does Clayton have any 4-star all-inclusive resorts?
Use our filters to look for all-inclusive Clayton resorts where your room, food, daily entertainment and more are provided for in the purchase price. Can’t find anything available? You can also kick back and relax in sophisticated surroundings at other excellent 4-star stays in the city. The Cheshire and Le Méridien St. Louis Clayton are two popular options.
What are the top 4-star apartments in Clayton?
Prepare to enjoy Clayton like a local at one of our 4-star apartments. Featuring a garden and individually decorated rooms, Tower Grove Getaways By Namastay is a great pick in this amazing destination. Or spend your stay at Hickory B - 1 Bedroom Apts and make use of a fireplace and a deck.
What are the top 4-star hotels in downtown Clayton?
Stay at Le Méridien St. Louis Clayton and you’ll be conveniently placed to experience the best of downtown Clayton. Located about 2 kilometers northwest from the city center, this 4-star hotel also comes with a swimming pool and a garden.