Find 4 Star Hotels in Clayton, MO from AED 323
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Compare Clayton 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/d8601c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
8.4 out of 10, Very Good, (3575)
The price is AED 400
AED 472 total
includes taxes & fees
6 Feb - 7 Feb
![Room](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/6e778fbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.2 out of 10, Wonderful, (935)
The price is AED 592
AED 710 total
includes taxes & fees
20 Feb - 21 Feb
![Property entrance](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/4c09ced4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
River City Casino & Hotel
River City Casino & Hotel
9.0 out of 10, Wonderful, (1064)
The price is AED 323
AED 417 total
includes taxes & fees
6 Feb - 7 Feb
![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8800/8738/eb9f8f16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
8.2 out of 10, Very Good, (1002)
The price is AED 612
AED 728 total
includes taxes & fees
12 Feb - 13 Feb
![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/fe8445aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Moonrise Hotel
Moonrise Hotel
9.0 out of 10, Wonderful, (1628)
The price is AED 526
AED 625 total
includes taxes & fees
19 Feb - 20 Feb
![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8700/8668/49bebc71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
DoubleTree by Hilton St. Louis Airport
DoubleTree by Hilton St. Louis Airport
7.8 out of 10, Good, (663)
The price is AED 356
AED 418 total
includes taxes & fees
9 Feb - 10 Feb
![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/2811db1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
The Cheshire
The Cheshire
8.4 out of 10, Very Good, (1002)
The price is AED 503
AED 597 total
includes taxes & fees
18 Feb - 19 Feb
![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
8.2 out of 10, Very Good, (1004)
The price is AED 422
AED 494 total
includes taxes & fees
21 Feb - 22 Feb
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Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
![Four Seasons Hotel St Louis](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/31480ab7_y.jpg?impolicy=resizecrop&rw=402&ra=fit)
Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
The price is AED 1,414 per night from Feb 6 to Feb 7
AED 1,414
AED 1,654 total
includes taxes & fees
6 Feb - 7 Feb
9.4/10 Exceptional! (982 reviews)
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Recent reviews of Clayton hotels
Recent reviews of Clayton hotels
![River City Casino & Hotel](http://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/4c09ced4_y.jpg)
River City Casino & Hotel
5/5 Excellent
"Beautiful the room is amazing! "
A verified traveler stayed at River City Casino & Hotel
Posted 2 days ago
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Clayton Hotels by Star Rating
Hotels in Clayton Neighborhoods
Stay near popular Clayton attractions
- Hotels near Chapel of St. Timothy And St. Titus
- Hotels near St. Louis Zoo
- Hotels near St. Louis Union Station
- Hotels near Busch Stadium
- Hotels near Gateway Arch
- Hotels near Washington University in St. Louis
- Hotels near Enterprise Center
- Hotels near Forest Park
- Hotels near City Museum
- Hotels near Barnes Jewish Hospital
- Hotels near Mississippi River
- Hotels near St. Louis University
- Hotels near Dome at America’s Center
- Hotels near America's Center Convention Complex
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Ameristar Casino St. Charles
- Hotels near Horseshoe St. Louis Casino
- Hotels near Westport Plaza
- Hotels near Fox Theater
- Hotels near St Charles Convention Center
More Hotel Options in Clayton
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- Hotel with a Concierge in Clayton
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- Hotels with Hot Tubs in Clayton
- Hotels with WiFi in Clayton
- Hotels with a Pool in Clayton
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- Luxury Hotels in Clayton
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- Romantic Hotels in Clayton
- Shopping Hotels in Clayton
Explore more hotels
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Moonrise Hotel
- The Wildwood Hotel
- Sonesta ES Suites St. Louis - Chesterfield
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Ameristar Casino Resort and Spa
- The Last Hotel
- Pear Tree Inn St. Louis Airport
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Live by Loews - St.Louis
- Home2 Suites by Hilton St. Louis/Forest Park
- Hilton Pennywell St. Louis at the Arch
- Pear Tree Inn St. Louis Near Union Station
- Holiday Inn St. Louis - Downtown Conv Ctr, an IHG Hotel
- Renaissance St. Louis Airport Hotel
- The Cheshire
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Four Seasons Hotel St Louis
- DoubleTree by Hilton St. Louis Forest Park
- Drury Inn & Suites St. Louis Union Station