Find Luxury Hotels in Clayton, MO

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Check availability on Clayton Luxury Hotels

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Compare Clayton Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (529)
"Great place"
The price is AED 2,127
AED 2,477 total
includes taxes & fees
15 May - 16 May
The Ritz-Carlton, St. Louis

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2941)
"A great hotel with great service and food. "
The price is AED 384
AED 447 total
includes taxes & fees
1 Jun - 2 Jun
Clayton Plaza Hotel & Extended Stay

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (596)
"Great stay! "
The price is AED 585
AED 687 total
includes taxes & fees
18 May - 19 May
Le Méridien St. Louis Clayton

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (561)
"The hotel has is nice and quiet. "
The price is AED 514
AED 610 total
includes taxes & fees
25 May - 26 May
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in Clayton?
While you’re visiting, you might want to think about enjoying the museums and sporting events, which Clayton is known for.
What's the best luxury place to stay in Clayton?
The Ritz-Carlton, St. Louis is a luxury hotel with spa services and valet parking, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
What's the best time to vacation in Clayton?
The hottest months are usually July and August with an average temperature of 76°F,
  • Coldest months: January, February, December, and March
  • Driest months: January, February, December, and November
  • Rainiest months: April, May, June, and August
What's there to see and do in Clayton?
Experience Clayton with a stop at Chapel of St. Timothy And St. Titus, Concordia Seminary, Enterprise Center, and St. Louis Zoo. If you have extra time while you’re in the area, you might want to see St. Louis Union Station and Busch Stadium.
How can I get around Clayton?
It’s easier to get around town comfortably when you know your options. Head to Clayton Station for metro transit.