Find Resorts & Hotels with Spas in Charleston, MO

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Charleston Resorts & Hotels with Spas

Tonight
23 Apr - 24 Apr
Tomorrow
24 Apr - 25 Apr
This weekend
25 Apr - 27 Apr
Next weekend
2 May - 4 May

Compare Charleston Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (377)
"Customer service is what sets them apart."
The price is AED 261
AED 290 total
includes taxes & fees
29 Apr - 30 Apr
Quality Inn Charleston - Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (550)
"The carpet in the room needs to be vacuumed."
The price is AED 241
AED 268 total
includes taxes & fees
24 Apr - 25 Apr
Super 8 by Wyndham Charleston/Sikeston East MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Charleston

Frequently asked questions

Looking for a spa hotel in Charleston?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Check out the opera and restaurants in Charleston—your day trip starts here. Be sure to pay a visit to the churches during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Charleston?
Among Expedia’s 3 accommodation options in Charleston, there is 1 spa hotel.
What's there to see and do in Charleston?
Experience all that Charleston has to offer when you visit Mississippi River, Ohio River, and The Book Bug. If you have a bit of extra time while you’re in the area, you might want to check out Mound City National Cemetery and Columbus-Belmont State Park.
What is a Charleston spa hotel?
Spa hotels in Charleston provide lodging and have an on-site spa offering services like facials and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.