Find 4 Star Hotels in Texas Medical Center, TX from AED 279
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Texas Medical Center 4 Star Hotels
Compare Texas Medical Center 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
8.4 out of 10, Very Good, (3323)
The price is AED 393
AED 460 total
includes taxes & fees
12 May - 13 May

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
8.2 out of 10, Very Good, (2009)
The price is AED 497
AED 585 total
includes taxes & fees
17 May - 18 May

The Whitehall Houston
The Whitehall Houston
8.4 out of 10, Very Good, (1415)
The price is AED 441
AED 516 total
includes taxes & fees
24 May - 25 May

Blossom Hotel Houston
Blossom Hotel Houston
9.2 out of 10, Wonderful, (3292)
The price is AED 463
AED 542 total
includes taxes & fees
18 May - 19 May

The Royal Sonesta Houston Galleria
The Royal Sonesta Houston Galleria
8.2 out of 10, Very Good, (1010)
The price is AED 507
AED 688 total
includes taxes & fees
16 May - 17 May

The Westin Oaks Houston at the Galleria
The Westin Oaks Houston at the Galleria
9.0 out of 10, Wonderful, (1003)
The price is AED 790
AED 1,043 total
includes taxes & fees
23 May - 24 May

Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District
9.0 out of 10, Wonderful, (1664)
The price is AED 890
AED 1,193 total
includes taxes & fees
18 May - 19 May

Hilton Americas-Houston
Hilton Americas-Houston
9.2 out of 10, Wonderful, (1268)
The price is AED 555
AED 658 total
includes taxes & fees
6 Jun - 7 Jun
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Texas Medical Center.

The Post Oak Hotel at Uptown Houston
1600 West Loop South, Houston, TX
The price is AED 1,983 per night from May 26 to May 27
AED 1,983
AED 2,321 total
26 May - 27 May
includes taxes & fees
9.4/10 Exceptional! (737 reviews)
Still don't see what you're looking for?
See all properties in Texas Medical Center.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Texas Medical Center hotels
Recent reviews of Texas Medical Center hotels

Hilton Americas-Houston
5/5 Excellent
"The hotel was wonderful, the staff was friendly and helpful."
A verified traveler stayed at Hilton Americas-Houston
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Texas Medical Center Hotels by Star Rating
Hotels in Texas Medical Center Neighborhoods
Stay near popular Texas Medical Center attractions
- Hotels near MD Anderson Cancer Center
- Hotels near NRG Stadium
- Hotels near Toyota Center
- Hotels near George R. Brown Convention Center
- Hotels near Daikin Park
- Hotels near Rice University
- Hotels near University of Houston
- Hotels near Memorial City Mall
- Hotels near Houston Zoo
- Hotels near NRG Park
- Hotels near Westheimer Rd
- Hotels near Downtown Aquarium
- Hotels near CityCentre
- Hotels near Sugar Land Town Square
More Hotel Options in Texas Medical Center
- Adventure Hotels in Texas Medical Center
- Business Hotels in Texas Medical Center
- Cheap Hotels in Texas Medical Center
- Family Hotels in Texas Medical Center
- Golf Hotels in Texas Medical Center
- Hotel Wedding Venues in Texas Medical Center
- Hotel with a Concierge in Texas Medical Center
- Hotels with Bars in Texas Medical Center
- Hotels with Free Parking in Texas Medical Center
- Hotels with Hot Tubs in Texas Medical Center
- Hotels with WiFi in Texas Medical Center
- Hotels with a Pool in Texas Medical Center
- Hotels with an Indoor Pool in Texas Medical Center
- Luxury Hotels in Texas Medical Center
- Pet-friendly Hotels in Texas Medical Center
- Resorts & Hotels with Spas in Texas Medical Center
- Shopping Hotels in Texas Medical Center
- Winery Hotels in Texas Medical Center
Explore more hotels
- Club Quarters Hotel Downtown, Houston
- Hyatt Place Houston-North
- Holiday Inn Houston Downtown by IHG
- DoubleTree by Hilton Hotel & Suites Houston by the Galleria
- Heritage Place Houston Brookhollow
- Hilton Americas-Houston
- Magnolia Hotel Houston, A Tribute Portfolio Hotel
- The Whitehall Houston
- Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
- Sonesta Hotel Houston IAH Airport
- The Royal Sonesta Houston Galleria
- C. Baldwin, Curio Collection by Hilton
- Cambria Hotel Houston Downtown Convention Center
- Houston Marriott Westchase
- DoubleTree by Hilton Hotel Houston - Greenway Plaza
- Marriott Marquis Houston
- Hyatt Regency Houston Downtown
- Hyatt Place Houston Downtown
- Hotel Ylem
- Hyatt Regency Houston/Galleria