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Find hotels in South Main, Houston from AED 278

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Discover 6,150 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Club Quarters Hotel Downtown, Houston
Exterior
Club Quarters Hotel Downtown, Houston
4.0 star property
8.2 out of 10, Very Good, (3074)
"Had a good time "
The price is AED 363
AED 413 total
includes taxes & fees
12 Dec - 13 Dec
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.0 out of 10, Very Good, (1539)
"Very old building , old rooms, bathrooms in great need of major update. View and window presence not nice at all. Bed and pillows great…clean room, great location hotel."
The price is AED 422
AED 489 total
includes taxes & fees
12 Dec - 13 Dec
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston
Exterior
The Whitehall Houston
4.0 star property
8.4 out of 10, Very Good, (1083)
"Website says pool is all seasons but we were told it was closed for the season. Otherwise happy with the stay."
The price is AED 466
AED 532 total
includes taxes & fees
24 Nov - 25 Nov
The Whitehall Houston
Blossom Hotel Houston
Room
Blossom Hotel Houston
4.0 star property
9.2 out of 10, Wonderful, (2825)
"Very nice property "
The price is AED 487
AED 549 total
includes taxes & fees
27 Nov - 28 Nov
Blossom Hotel Houston
Holiday Inn Houston Downtown, an IHG Hotel
Exterior
Holiday Inn Houston Downtown, an IHG Hotel
3.0 star property
8.6 out of 10, Excellent, (1009)
"The staff was very friendly and easy check in. Room was clean and everything was conveniently located near the hotel"
The price is AED 278
AED 390 total
includes taxes & fees
24 Nov - 25 Nov
Holiday Inn Houston Downtown, an IHG Hotel
Marriott Marquis Houston
Exterior
Marriott Marquis Houston
4.0 star property
8.8 out of 10, Excellent, (1013)
"I stayed to see Tonight’s Conversation, I valet parked my truck, enjoyed my stay, ordered room service; which was complementary and deducted from my final bill. I LOVED it. You definitely get what you paid for. I didn’t get a chance to get in the pool, but I will be back. I also had a magnificent view of the City from the 17th floor. "
The price is AED 742
AED 977 total
includes taxes & fees
25 Nov - 26 Nov
Marriott Marquis Houston
Hilton Americas-Houston
Exterior
Hilton Americas-Houston
4.0 star property
9.2 out of 10, Wonderful, (1123)
"This was the perfect hotel to stay at for a concert at the Toyota center! Will definitely stay here again! "
The price is AED 559
AED 652 total
includes taxes & fees
26 Nov - 27 Nov
Hilton Americas-Houston
Hyatt Regency Houston Downtown
Room
Hyatt Regency Houston Downtown
4.0 star property
9.2 out of 10, Wonderful, (1008)
"Great!"
The price is AED 606
AED 732 total
includes taxes & fees
25 Nov - 26 Nov
Hyatt Regency Houston Downtown
Hyatt Place Houston Downtown
Exterior
Hyatt Place Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (1412)
"I love it"
The price is AED 427
AED 498 total
includes taxes & fees
24 Nov - 25 Nov
Hyatt Place Houston Downtown
C. Baldwin, Curio Collection by Hilton
Exterior
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.4 out of 10, Very Good, (915)
"Beautiful, modern hotel!"
The price is AED 590
AED 774 total
includes taxes & fees
1 Dec - 2 Dec
C. Baldwin, Curio Collection by Hilton
Rusk House Serviced Apartments
Property amenity
Rusk House Serviced Apartments
4.5 star property
9.2 out of 10, Wonderful, (77)
"It was great… I read reviews before I went & they lied ! The property was amazing! Rooms were very spacious! I will definitely be back soon "
The price is AED 514
AED 585 total
includes taxes & fees
18 Nov - 19 Nov
Rusk House Serviced Apartments
Le Meridien Houston Downtown
Exterior
Le Meridien Houston Downtown
4.0 star property
8.6 out of 10, Excellent, (862)
"We enjoyed our stay "
The price is AED 526
AED 600 total
includes taxes & fees
24 Nov - 25 Nov
Le Meridien Houston Downtown
Hyatt Place Houston Medical Center
Exterior
Hyatt Place Houston Medical Center
3.0 star property
9.0 out of 10, Wonderful, (1145)
"I love the hotel very nice and kid friendly. The only thing I did not like was the parking garage seems very crowded and tight to park."
The price is AED 415
AED 477 total
includes taxes & fees
17 Nov - 18 Nov
Hyatt Place Houston Medical Center
Cambria Hotel Houston Downtown Convention Center
Exterior
Cambria Hotel Houston Downtown Convention Center
3.0 star property
8.8 out of 10, Excellent, (1426)
"The only con is the construction around and in the property. "
The price is AED 426
AED 489 total
includes taxes & fees
26 Nov - 27 Nov
Cambria Hotel Houston Downtown Convention Center
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
Exterior
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
3.5 star property
7.4 out of 10, Good, (1008)
"Will stay again "
The price is AED 327
AED 382 total
includes taxes & fees
12 Dec - 13 Dec
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
Moxy Houston Downtown
Front of property
Moxy Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (256)
"The hotel itself was great and the location was convenient. The beds are not comfortable and the rooms are rather small. However the smell of urine reaps the area due to the huge presence of homeless people walking and sleeping on the sidewalks. I wish there were more options close by to eat. The nightlife on the strip is awesome just needs more happy hour times. Overall I enjoyed the stay. "
The price is AED 364
AED 424 total
includes taxes & fees
24 Nov - 25 Nov
Moxy Houston Downtown
Thompson Houston, by Hyatt
Exterior
Thompson Houston, by Hyatt
4.0 star property
9.2 out of 10, Wonderful, (90)
"The service from every staff was amazing!"
The price is AED 1,021
AED 1,316 total
includes taxes & fees
25 Nov - 26 Nov
Thompson Houston, by Hyatt
The Royal Sonesta Houston Galleria
Exterior
The Royal Sonesta Houston Galleria
4.0 star property
8.2 out of 10, Very Good, (1010)
"We requested a room cleaning. Went to breakfast and when we returned, it was done. Excellent service. "
The price is AED 480
AED 642 total
includes taxes & fees
24 Nov - 25 Nov
The Royal Sonesta Houston Galleria
InterContinental Houston, an IHG Hotel
Exterior
InterContinental Houston, an IHG Hotel
4.0 star property
9.2 out of 10, Wonderful, (1004)
"Good size room. Elevator kind of noisy at night. Unable to adjust room temperature "
The price is AED 466
AED 601 total
includes taxes & fees
28 Nov - 29 Nov
InterContinental Houston, an IHG Hotel
The Chifley Houston, Tapestry Collection by Hilton
Lobby
The Chifley Houston, Tapestry Collection by Hilton
4.0 star property
8.8 out of 10, Excellent, (1010)
"good"
The price is AED 528
AED 605 total
includes taxes & fees
24 Nov - 25 Nov
The Chifley Houston, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 68 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.