South Main, TX

Houston

Photo by Hazem Abdul

Popular places to visit


South Main Hotel Deals

Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical Center
3.5 out of 5
8686 Kirby Drive, Houston, TX
The price is AED 510 per night from Mar 24 to Mar 25
AED 510
AED 597 total
includes taxes & fees
24 Mar - 25 Mar
Stay at this 3.5-star business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
7.2/10 Good! (1,001 reviews)
Handicapped shower
"Odd shower, kept getting water everywhere as it was a handicap bathroom (despite us not being handicapped) so kept running out of towels and the floor was always wet"

Reviewed on 17 February 2025

Wyndham Houston near NRG Park/Medical Center
Comfort Suites near Texas Medical Center - NRG Stadium
Comfort Suites near Texas Medical Center - NRG Stadium
2.5 out of 5
1055 Mcnee Rd, Houston, TX
The price is AED 380 per night from Mar 27 to Mar 28
AED 380
AED 445 total
includes taxes & fees
27 Mar - 28 Mar
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (788 reviews)
"Always stay here for price and convenience"

Reviewed on 27 February 2025

Comfort Suites near Texas Medical Center - NRG Stadium
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
The price is AED 447 per night from Apr 4 to Apr 5
AED 447
AED 527 total
includes taxes & fees
4 Apr - 5 Apr
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,800 reviews)
"yy"

Reviewed on 3 March 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
The price is AED 393 per night from Apr 3 to Apr 4
AED 393
AED 460 total
includes taxes & fees
3 Apr - 4 Apr
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,136 reviews)
"Water pressure was pretty bad in the showers but other than that it was good"

Reviewed on 26 February 2025

Club Quarters Hotel Downtown, Houston
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
The price is AED 494 per night from Apr 3 to Apr 4
AED 494
AED 577 total
includes taxes & fees
3 Apr - 4 Apr
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,251 reviews)
"Very friendly and helpful staff. Nice hotel but little dated on rooms w/ wear and tear showing up in bathroom. Very comfortable beds but a there was too much road noise by this somewhat of a light sleeper."

Reviewed on 25 February 2025

The Whitehall Houston
Holiday Inn Houston Downtown, an IHG Hotel
Holiday Inn Houston Downtown, an IHG Hotel
3 out of 5
1616 Main St, Houston, TX
The price is AED 393 per night from Mar 30 to Mar 31
AED 393
AED 524 total
includes taxes & fees
30 Mar - 31 Mar
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,033 reviews)
"Overall was good; the bathroom could have been bigger"

Reviewed on 1 March 2025

Holiday Inn Houston Downtown, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around South Main

#race

Astrodome

4/5(276 area reviews)

If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Astrodome and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.

Astrodome
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Texas Medical Center

4/5(566 area reviews)

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Texas Medical Center
Hermann Park featuring landscape views and a park

Houston Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park featuring landscape views and a park

South Central Houston

4.5/5(74 area reviews)

If you're spending time in South Central Houston, check out sights like Houston Zoo or Children's Museum of Houston and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection which includes art and interior views

Montrose

4/5(128 area reviews)

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Buffalo Bayou Park while you're exploring the area.

Montrose
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Greater Third Ward

4/5(23 area reviews)

While you're in Greater Third Ward, take in top sights like Fertitta Center or 2209 Dowling Street, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

Greater Third Ward

South Main, TX

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