Find Resorts & Hotels with Spas in Santee, SC

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Check availability on Santee Resorts & Hotels with Spas

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Property amenity

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1005)
"Very nice place for an overnight stay. "
The price is AED 478
AED 530 total
includes taxes & fees
1 Jun - 2 Jun
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1003)
"Friendly staff, nice breakfast. "
The price is AED 501
AED 556 total
includes taxes & fees
25 May - 26 May
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1292)
"Amazing stay"
The price is AED 275
AED 306 total
includes taxes & fees
18 May - 19 May
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (521)
"The property needs some work but it was quiet and close to a few restaurants we could walk to."
The price is AED 281
AED 312 total
includes taxes & fees
18 May - 19 May
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (880)
"Second time staying there , very nice place "
The price is AED 474
AED 526 total
includes taxes & fees
1 Jun - 2 Jun
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (621)
"Older property but ok for the price. "
The price is AED 220
AED 245 total
includes taxes & fees
3 Jun - 4 Jun
Travelodge by Wyndham Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (414)
"The hotel is very clean. The staff are very friendly. Parking is wonderful."
The price is AED 404
AED 448 total
includes taxes & fees
1 Jun - 2 Jun
Tru By Hilton Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (605)
"This was probably a nice place at one point in time but its in desperate need of a deep clean and remodel. Everything is outdated, dirty, and the breakfast was a joke"
The price is AED 246
AED 273 total
includes taxes & fees
3 Jun - 4 Jun
Red Roof Inn Santee
Super 8 by Wyndham Santee
Lobby

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (425)
"Great place. Easy to walk to places to eat "
The price is AED 275
AED 306 total
includes taxes & fees
18 May - 19 May
Super 8 by Wyndham Santee
Lake Marion 2Bed/2Bath Deluxe!
Interior

Lake Marion 2Bed/2Bath Deluxe!

2.5 star property
Lake Marion 2Bed/2Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee State Park. If you have a bit of extra time while you’re in the area, you might want to check out Santee National Golf Club and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.