Find Resorts & Hotels with Spas in Santee, SC

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Check availability on Santee Resorts & Hotels with Spas

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Lobby

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1001)
"The beds were super comfortable! The rooms were clean and modern and new. Breakfast was hot and ready BEFORE the 6 am time! Checkout was a breeze. Will definitely stay here again!"
The price is AED 525
AED 583 total
includes taxes & fees
23 Apr - 24 Apr
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1002)
"Great and convenient "
The price is AED 556
AED 617 total
includes taxes & fees
23 Apr - 24 Apr
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1296)
"room had a musty smell cleared after 30 minutes"
The price is AED 294
AED 326 total
includes taxes & fees
17 Apr - 18 Apr
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Room, 2 Double Beds, Non Smoking | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (519)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
The price is AED 303
AED 336 total
includes taxes & fees
17 Apr - 18 Apr
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (872)
"The property and local staff are outstanding. The national reservation line, though may inhibit me from ever staying at an IHG property again."
The price is AED 426
AED 473 total
includes taxes & fees
13 May - 14 May
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (606)
"For the most part, everything was good.Except for the half used shampoo bottle in the shower left from whoever was there before. "
The price is AED 224
AED 249 total
includes taxes & fees
20 Apr - 21 Apr
Travelodge by Wyndham Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (396)
"This property was clean & convenient; the staff was amazing! Breakfast was great and we had a wonderful experience overall. "
The price is AED 404
AED 448 total
includes taxes & fees
11 May - 12 May
Tru By Hilton Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (603)
"Comfortable , clean and friendly. Very convenient location."
The price is AED 257
AED 285 total
includes taxes & fees
17 Apr - 18 Apr
Red Roof Inn Santee
Super 8 by Wyndham Santee
Exterior

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (419)
"Clean and tidy place bed a little lumpy but overall everything was good would I stay here again? Yes"
The price is AED 275
AED 306 total
includes taxes & fees
17 Apr - 18 Apr
Super 8 by Wyndham Santee
Lake Marion 2Bed/2Bath Deluxe!
Interior

Lake Marion 2Bed/2Bath Deluxe!

2.5 star property
Lake Marion 2Bed/2Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee National Golf Club. If you have a bit of extra time while you’re in the area, you might want to check out Santee State Park and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.