Find Resorts & Hotels with Spas in Santee, SC

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Check availability on Santee Resorts & Hotels with Spas

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Lobby

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1002)
"Everything was very clean and comfortable and the staff were very friendly and helpful. There were lots of choices for breakfast and the food was very good."
The price is AED 492
AED 546 total
includes taxes & fees
9 Mar - 10 Mar
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Room

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1003)
"Lovely stay with superior service. One of the most comfortable beds ever slept in. Would surely recommend."
The price is AED 484
AED 537 total
includes taxes & fees
12 Mar - 13 Mar
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Exterior

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1276)
"Clean comfortable, slept well."
The price is AED 275
AED 306 total
includes taxes & fees
23 Feb - 24 Feb
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Room

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (510)
"Great cheesesteak and friendly management. "
The price is AED 296
AED 329 total
includes taxes & fees
2 Mar - 3 Mar
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (839)
"Loved the friendliness of the staff and the open airiness of the lobby. Shower curtain did not fit the shower. "
The price is AED 381
AED 423 total
includes taxes & fees
26 Feb - 27 Feb
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (589)
"Great"
The price is AED 220
AED 245 total
includes taxes & fees
23 Feb - 24 Feb
Travelodge by Wyndham Santee
Tru By Hilton Santee
Exterior

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (340)
"The noise was terrible from the expressway."
The price is AED 342
AED 379 total
includes taxes & fees
16 Mar - 17 Mar
Tru By Hilton Santee
Red Roof Inn Santee
Room

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (594)
"The only thing I didn't like was the refrigerator wasn't working other than that everything was okay."
The price is AED 246
AED 273 total
includes taxes & fees
23 Feb - 24 Feb
Red Roof Inn Santee
Super 8 by Wyndham Santee
Exterior

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (413)
"Great place. Easy to walk to places to eat "
The price is AED 275
AED 306 total
includes taxes & fees
23 Feb - 24 Feb
Super 8 by Wyndham Santee
Lake Marion 3Bed/3Bath Deluxe!
Bathroom

Lake Marion 3Bed/3Bath Deluxe!

2.5 star property
Lake Marion 3Bed/3Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee State Park. If you have a bit of extra time while you’re in the area, you might want to check out Lake Marion and Santee National Golf Club.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.