Find Resorts & Hotels with Spas in Santee, SC

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Check availability on Santee Resorts & Hotels with Spas

Tonight
4 May - 5 May
Tomorrow
5 May - 6 May
Next weekend
9 May - 11 May
In two weeks
16 May - 18 May

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Property amenity

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1007)
"Very nice place for an overnight stay. "
The price is AED 525
AED 583 total
includes taxes & fees
11 May - 12 May
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1000)
"Friendly staff, nice breakfast. "
The price is AED 502
AED 557 total
includes taxes & fees
25 May - 26 May
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1299)
"Great staff comfy stay "
The price is AED 294
AED 326 total
includes taxes & fees
5 May - 6 May
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (521)
"The property needs some work but it was quiet and close to a few restaurants we could walk to."
The price is AED 301
AED 334 total
includes taxes & fees
11 May - 12 May
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (878)
"Second time staying there , very nice place "
The price is AED 481
AED 534 total
includes taxes & fees
2 Jun - 3 Jun
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (615)
"Close to highway but had an cheap feel to the rooms, furniture, toilet"
The price is AED 220
AED 245 total
includes taxes & fees
3 Jun - 4 Jun
Travelodge by Wyndham Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (402)
"Very nice stay when on the way to Florida "
The price is AED 404
AED 448 total
includes taxes & fees
18 May - 19 May
Tru By Hilton Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (603)
"Great place for the price to stop for the night. "
The price is AED 246
AED 273 total
includes taxes & fees
1 Jun - 2 Jun
Red Roof Inn Santee
Super 8 by Wyndham Santee
Lobby

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (425)
"Great place. Easy to walk to places to eat "
The price is AED 275
AED 306 total
includes taxes & fees
5 May - 6 May
Super 8 by Wyndham Santee
Lake Marion 2Bed/2Bath Deluxe!
Interior

Lake Marion 2Bed/2Bath Deluxe!

2.5 star property
Lake Marion 2Bed/2Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee State Park. If you have a bit of extra time while you’re in the area, you might want to check out Santee National Golf Club and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.