Find Family Hotels in Santee, SC

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Santee Family Hotels

Tonight
1 Feb - 2 Feb
Tomorrow
2 Feb - 3 Feb
Next weekend
7 Feb - 9 Feb
In two weeks
14 Feb - 16 Feb

Compare Santee Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (940)
"Convenient to I95"
The price is AED 387
AED 430 total
includes taxes & fees
9 Feb - 10 Feb
Comfort Inn & Suites Santee
Hampton Inn Santee-I-95
Room

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1007)
"Really good "
The price is AED 484
AED 537 total
includes taxes & fees
9 Feb - 10 Feb
Hampton Inn Santee-I-95
Best Western Plus Santee Inn
Exterior

Best Western Plus Santee Inn

2.5 star property
8.6 out of 10, Excellent, (1003)
"Excellent service, check (early) was seemless. Made it very easy after driving all night. "
The price is AED 406
AED 451 total
includes taxes & fees
9 Feb - 10 Feb
Best Western Plus Santee Inn
Holiday Inn Santee, an IHG Hotel
Exterior

Holiday Inn Santee, an IHG Hotel

3.0 star property
8.2 out of 10, Very Good, (834)
"good experience, quiet, even though room was right by elevator. Pillows are so soft."
The price is AED 390
AED 433 total
includes taxes & fees
9 Feb - 10 Feb
Holiday Inn Santee, an IHG Hotel
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (306)
"Check in was easy."
The price is AED 197
AED 219 total
includes taxes & fees
2 Mar - 3 Mar
Econo Lodge
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (585)
"comfortable and convenient"
The price is AED 220
AED 245 total
includes taxes & fees
3 Feb - 4 Feb
Travelodge by Wyndham Santee
Super 8 by Wyndham Santee
Exterior

Super 8 by Wyndham Santee

2.0 star property
6.6 out of 10, (412)
"Close to exit. Easy checkin "
The price is AED 275
AED 306 total
includes taxes & fees
3 Feb - 4 Feb
Super 8 by Wyndham Santee
Baymont by Wyndham Santee
Exterior

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1286)
"Our stay was a quick, reasonably priced one night stay. After driving 16 hours, it was nice to find our room very clean, no odors and a heater with actual temperature controls versus hi-lo control. The continental breakfast was nice allowing us an early start the next day. The location was conveniently right off the highway, with easy access to gas stations and restaurants. "
The price is AED 275
AED 306 total
includes taxes & fees
3 Feb - 4 Feb
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Room

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (509)
"Nice room staf was excellent and i love the bars plaing pools and food was amazing try chicken wings "
The price is AED 312
AED 346 total
includes taxes & fees
10 Feb - 11 Feb
Ramada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santee

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you’ve been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Comfort Inn & Suites Santee is a hotel with free parking and free buffet breakfast, and it’s a top choice on Expedia for families. Fairfield Inn & Suites by Marriott Santee is another choice for your stay with the kids.
How many hotels that welcome families will I find in Santee?
Expedia has 10 family-friendly hotels and other accommodations in Santee.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you might want to check out some kid-friendly attractions such as Santee Outlets and Santee Indian Mound and Fort Watson Site. Make sure you have lots of time for activities like Orangeburg County Library Mentor Branch and Santee State Park.