Find Family Hotels in Santee, SC

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Santee Family Hotels

This weekend
Next weekend

Compare Santee Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (980)
" decent breakfast. enough towels. - outdated noisy A/C won't let you sleep well (bring ear plugs). small old TVs on the wall. "
The price is AED 403
AED 447 total
includes taxes & fees
6 May - 7 May
Comfort Inn & Suites Santee

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1000)
"This property was very clean. The staff were very pleasant when checking in. The only reason I gave it a 4 star was because the air conditioner was old at night and the toilet paper is rough. Otherwise a very wonderful place. "
The price is AED 533
AED 591 total
includes taxes & fees
25 May - 26 May
Hampton Inn Santee-I-95

Best Western Plus Santee Inn

2.5 star property
8.8 out of 10, Excellent, (1002)
"Nice older motel. Very well maintained. Comfy bed. Very friendly helpful staff. Only reason I didn’t give it a perfect score was the old stinky carpet in the room."
The price is AED 421
AED 468 total
includes taxes & fees
11 May - 12 May
Best Western Plus Santee Inn

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (877)
"Second time staying there , very nice place "
The price is AED 466
AED 518 total
includes taxes & fees
25 May - 26 May
Holiday Inn Santee by IHG

Econo Lodge

2.0 star property
6.4 out of 10, (307)
"Check in was easy."
The price is AED 220
AED 244 total
includes taxes & fees
11 May - 12 May
Econo Lodge

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (610)
"Staff was great room was clean and comfy. For 65 bucks was great ty"
The price is AED 224
AED 249 total
includes taxes & fees
27 Apr - 28 Apr
Travelodge by Wyndham Santee

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (421)
"Property is dated but well maintained. "
The price is AED 275
AED 306 total
includes taxes & fees
27 Apr - 28 Apr
Super 8 by Wyndham Santee

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1294)
"Nice remodeled rooms. Spacious comfortable with frig and micro. Bed was comfy and nice breakfast Clise to things to do and restaurants. "
The price is AED 294
AED 326 total
includes taxes & fees
27 Apr - 28 Apr
Baymont by Wyndham Santee

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (521)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
The price is AED 303
AED 336 total
includes taxes & fees
1 May - 2 May
Ramada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santee

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you’ve been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it’s a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
How many hotels that welcome families will I find in Santee?
Expedia has 10 family-friendly hotels and other accommodations in Santee.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you might want to check out some kid-friendly attractions such as Santee Outlets and Santee Indian Mound and Fort Watson Site. Make sure you have lots of time for activities like Orangeburg County Library Mentor Branch and Taw Caw Creek.