Find all hotels by Independent in Santee, SC from AED 220
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Compare rooms and suites by Independent in Santee with rates, reviews, and availability. Most hotels are fully refundable.
Recent reviews of Santee hotels
Recent reviews of Santee hotels
5/5 Excellent
"Nice one night stay!"
A verified traveler stayed at Tru By Hilton Santee
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Santee Hotels by Brand
Hotels near popular Santee Attractions
- Hotels near Santee State Park
- Hotels near Santee Cooper Country Club
- Hotels near Santee National Golf Club
- Hotels near Santee Outlets
- Hotels near Congaree National Park
- Hotels near Lake Marion
- Hotels near South Carolina State University
- Hotels near Santee National Wildlife Refuge
- Hotels near Wyboo Golf Club
- Hotels near Santee Indian Mound and Fort Watson Site
More Hotel Options in Santee
- Adventure Hotels (3)
- Beach Hotels (1)
- Business Hotels (11)
- Cheap Hotels (7)
- Family Hotels (10)
- Golf Hotels (5)
- Hotel with a Concierge (1)
- Hotels with Bars (6)
- Hotels with Free Parking (11)
- Hotels with Hot Tubs (3)
- Hotels with WiFi (13)
- Hotels with a Pool (10)
- Hotels with an Indoor Pool (1)
- Hotels with smoking rooms (1)
- Luxury Hotels (5)
- Pet-friendly Hotels (10)
- Resorts & Hotels with Spas (2)
- Shopping Hotels (11)
Explore more hotels
- Red Roof Inn Santee
- Wyndham Vacation Resorts Lake Marion
- Rodeway Inn Santee I-95
- Executive 2 BR/2 BA Lakefront Corner Suite Condo
- Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
- SureStay Hotel by Best Western Manning
- Days Inn by Wyndham St George
- Travelodge by Wyndham Orangeburg
- Tru by Hilton Orangeburg
- SpringHill Suites by Marriott Orangeburg
- Baymont by Wyndham Orangeburg North
- Peach Tree Inn
- Super 8 by Wyndham, Orangeburg
- Fairfield Inn by Marriott Orangeburg
- Red Roof Inn St George, SC
- Days Inn by Wyndham Orangeburg
- Comfort Inn & Suites
- Holiday Inn Express & Suites Orangeburg
- Quality Inn & Suites
- Inn at Orangeburg