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Find hotels in Santa Ana, Panama City from AED 97

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Check prices for these dates

Tonight
23 Apr - 24 Apr
Tomorrow
24 Apr - 25 Apr
This weekend
25 Apr - 27 Apr
Next weekend
2 May - 4 May

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Discover 1,399 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Casco View Apartments
Apartment (4) | Terrace/patio

Casco View Apartments

3.0 star property
9.6 out of 10, Exceptional, (28)
"Loved the pool and amenities (kitchen, washing machine, separate bedroom)"
The price is AED 223
AED 337 total
includes taxes & fees
30 Apr - 1 May
Casco View Apartments
Hostal La Cigarra
Reception

Hostal La Cigarra

2.5 star property
7.4 out of 10, Good, (44)
"A nice hostel very fairly priced, basic but clean and affordable "
The price is AED 97
AED 107 total
includes taxes & fees
27 Apr - 28 Apr
Hostal La Cigarra
Hotel República
Balcony

Hotel República

2.0 star property
6.6 out of 10, (168)
"The wifi is strong enough to use for work. "
The price is AED 119
AED 131 total
includes taxes & fees
27 Apr - 28 Apr
Hotel República
Casa Quijano 06 By Wynwood House
Apartment | Terrace/patio

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"Easy to find, seamless check-in "
The price is AED 284
AED 414 total
includes taxes & fees
13 May - 14 May
Casa Quijano 06 By Wynwood House
La Manzana by Wynwood House
Apartment (20) | Iron/ironing board, free WiFi, bed sheets

La Manzana by Wynwood House

3.5 star property
6.8 out of 10, (11)
"From the start, from not responding as per the terms which is 24 hours before to send email with codes, did not happen. Units not working, ac and toilet. Poor communication where only speak spanish. You are not receiving only Spanish speaking guest. Overall I would not even visit this place if it was offered free to me. Poor management"
The price is AED 198
AED 292 total
includes taxes & fees
28 Apr - 29 Apr
La Manzana by Wynwood House
ART CASCO The Hotel
Front of property

ART CASCO The Hotel

2.0 star property
4.0 out of 10, (2)
"Prácticamente el lugar es un motel no un hotel "
The price is AED 100
AED 110 total
includes taxes & fees
25 Apr - 26 Apr
ART CASCO The Hotel
Hotel Riazor
Single Room | Free WiFi, bed sheets

Hotel Riazor

3.0 star property
3.6 out of 10, (8)
"Buenas estadía, muy cerca de los lugares de interés, la sra Riatela excelente anfitriona."
Hotel Riazor
La Concordia Boutique Hotel
Exclusive House | Terrace/patio

La Concordia Boutique Hotel

4.0 star property
9.4 out of 10, Exceptional, (163)
"The room was beautiful but very loud. The A/C was great. The staff was friendly. The immediate neighborhood was run down. All the food and beverages in Casco Viejo were massively overpriced. Nothing was cheap."
The price is AED 598
AED 658 total
includes taxes & fees
2 May - 3 May
La Concordia Boutique Hotel
Hotel Casa Panamá
Balcony

Hotel Casa Panamá

4.0 star property
7.4 out of 10, Good, (528)
"Great"
The price is AED 195
AED 215 total
includes taxes & fees
25 May - 26 May
Hotel Casa Panamá
Oasis Hotel
Reception

Oasis Hotel

3.0 star property
8.4 out of 10, Very Good, (82)
"Great crash pad hotel in the heart of Casco Viejo. Hotel has huge rooms for a very good price, but they are a little on the older side. Staff was nice, room was clean, and you cannot beat the location. Hotel also has a rooftop bar with great views of the city. The Casco area is gorgeous, extremely safe, and has plenty of options for food and drink. Heads up - there are some clubs nearby and it can get pretty loud at night. It didn't bother me, but it may not be ideal for others."
The price is AED 218
AED 240 total
includes taxes & fees
28 Apr - 29 Apr
Oasis Hotel
American Trade Hotel
Front of property - evening/night

American Trade Hotel

4.5 star property
9.4 out of 10, Exceptional, (512)
"We loved this property! Not only is the location perfect for a visit to old Panama, but the property itself transforms you back to an old era of elegance and beauty. The staff are wonderful and the dining options wonderful for a stay."
The price is AED 871
AED 958 total
includes taxes & fees
1 May - 2 May
American Trade Hotel
Tantalo Hotel
Front of property - evening/night

Tantalo Hotel

3.5 star property
8.8 out of 10, Excellent, (249)
"Convenience and safety. Will get a better idea tomorrow with tour of area."
The price is AED 350
AED 385 total
includes taxes & fees
6 May - 7 May
Tantalo Hotel
Hotel La Compania, in the Unbound Collection by Hyatt
Rooftop terrace

Hotel La Compania, in the Unbound Collection by Hyatt

4.5 star property
9.8 out of 10, Exceptional, (205)
"Beautiful property."
The price is AED 1,207
AED 1,327 total
includes taxes & fees
27 Apr - 28 Apr
Hotel La Compania, in the Unbound Collection by Hyatt
Hotel Herrera
Luxury Room | In-room safe, desk, laptop workspace, blackout drapes

Hotel Herrera

3.0 star property
The price is AED 818
AED 900 total
includes taxes & fees
25 Apr - 26 Apr
Hotel Herrera
Hotel San Felipe
Terrace/patio

Hotel San Felipe

4.0 star property
9.4 out of 10, Exceptional, (145)
"The staff was great. Nice rooms. "
The price is AED 432
AED 475 total
includes taxes & fees
7 May - 8 May
Hotel San Felipe
Magnolia Inn
Living area

Magnolia Inn

2.0 star property
9.0 out of 10, Wonderful, (329)
"Room was large, beds comfortable, great a/c. This is a basic hotel (no hairdryer, no cups, no elevator, etc) but the location can’t be beat. "
The price is AED 275
AED 303 total
includes taxes & fees
27 Apr - 28 Apr
Magnolia Inn
Central Hotel Panama Casco Viejo
47-inch flat-screen TV with cable channels, TV

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (883)
"The hotel was lovely and staff very friendly. Great location. "
The price is AED 879
AED 967 total
includes taxes & fees
27 Apr - 28 Apr
Central Hotel Panama Casco Viejo
Amarla Boutique Hotel Casco Viejo
Exterior

Amarla Boutique Hotel Casco Viejo

3.0 star property
9.8 out of 10, Exceptional, (75)
"They are a very cute little boutique hotel in the heart of Casco Viejo. If you are looking for a charming little home feel, soak in the historic area with the classic balconies the shutters and brick walls filled with local and carefully selected art and decoration with the touch of luxury, look no further!"
The price is AED 618
AED 680 total
includes taxes & fees
5 May - 6 May
Amarla Boutique Hotel Casco Viejo
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (440)
"Simply Excellent!!!! Wonderful staff and beautiful place!! Loved it!"
The price is AED 1,074
AED 1,182 total
includes taxes & fees
1 May - 2 May
Sofitel Legend Casco Viejo, Panama City
Hotel Caribe
Outdoor pool, pool umbrellas, sun loungers

Hotel Caribe

3.0 star property
7.6 out of 10, Good, (254)
"Good, inexpensive and free breakfast! "
The price is AED 185
AED 204 total
includes taxes & fees
4 May - 5 May
Hotel Caribe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 95 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.