Photo by Isa

Find hotels in Santa Ana, Panama City from AED 97

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Tonight
2 Apr - 3 Apr
Tomorrow
3 Apr - 4 Apr
This weekend
4 Apr - 6 Apr
Next weekend
11 Apr - 13 Apr

Filter by

Guest rating
Guest rating
Star rating

Discover 1,389 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Casco View Apartments
Apartment (4) | Terrace/patio

Casco View Apartments

3.0 star property
9.6 out of 10, Exceptional, (24)
"Great accommodations. Great view. Great host. "
The price is AED 296
AED 417 total
includes taxes & fees
15 Apr - 16 Apr
Casco View Apartments
La Manzana by Wynwood House
Apartment (20) | Iron/ironing board, free WiFi, bed sheets

La Manzana by Wynwood House

3.5 star property
7.2 out of 10, Good, (9)
"From the start, from not responding as per the terms which is 24 hours before to send email with codes, did not happen. Units not working, ac and toilet. Poor communication where only speak spanish. You are not receiving only Spanish speaking guest. Overall I would not even visit this place if it was offered free to me. Poor management"
The price is AED 195
AED 288 total
includes taxes & fees
3 Apr - 4 Apr
La Manzana by Wynwood House
Casa Quijano 06 By Wynwood House
Apartment | Terrace/patio

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"Easy to find, seamless check-in "
The price is AED 279
AED 408 total
includes taxes & fees
13 Apr - 14 Apr
Casa Quijano 06 By Wynwood House
Hostal La Cigarra
Reception

Hostal La Cigarra

2.5 star property
7.4 out of 10, Good, (44)
"A nice hostel very fairly priced, basic but clean and affordable "
The price is AED 97
AED 107 total
includes taxes & fees
9 Apr - 10 Apr
Hostal La Cigarra
Hotel República
Balcony

Hotel República

2.0 star property
6.6 out of 10, (165)
"Nothing special but in a very convenient location. Could have been cleaner but not terrible."
The price is AED 119
AED 131 total
includes taxes & fees
9 Apr - 10 Apr
Hotel República
ART CASCO The Hotel
Front of property

ART CASCO The Hotel

2.0 star property
4.0 out of 10, (2)
"Prácticamente el lugar es un motel no un hotel "
The price is AED 100
AED 110 total
includes taxes & fees
3 Apr - 4 Apr
ART CASCO The Hotel
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2236)
"Very close to airport, friendly staff and a great resource to travelers"
The price is AED 397
AED 497 total
includes taxes & fees
25 Apr - 26 Apr
Crowne Plaza Panama Airport by IHG
Riande Aeropuerto Hotel & Casino
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1883)
"very nice property with a very good service close to airport."
The price is AED 395
AED 434 total
includes taxes & fees
3 Apr - 4 Apr
Riande Aeropuerto Hotel & Casino
Courtyard by Marriott Panama Metromall
Serves breakfast, lunch, and dinner

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (979)
"It was close to the airport shopping mall and staff was friendly and helpful "
The price is AED 397
AED 436 total
includes taxes & fees
13 Apr - 14 Apr
Courtyard by Marriott Panama Metromall
The Westin Panama
Outdoor pool, pool umbrellas, sun loungers

The Westin Panama

4.0 star property
8.8 out of 10, Excellent, (273)
"Great facility in the heart of the city"
The price is AED 724
AED 796 total
includes taxes & fees
4 Apr - 5 Apr
The Westin Panama
Aloft Panama
Exterior

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (791)
"Great place to stay if your traveling with family."
The price is AED 443
AED 487 total
includes taxes & fees
13 Apr - 14 Apr
Aloft Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1078)
"Love the staff"
The price is AED 673
AED 740 total
includes taxes & fees
2 May - 3 May
JW Marriott Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Outdoor pool, pool umbrellas, sun loungers

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1103)
"Great location and nearby dining"
The price is AED 425
AED 467 total
includes taxes & fees
1 May - 2 May
Ramada Plaza By Wyndham Panama Punta Pacífica
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (441)
"The Residence inn in Panama is at a great location. Easy access to great restaurants, close to a 5 star mall, and great location for rental launch into the rest of Panama. The rooms are clean and roomy. Great kitchen with all you might need . The breakfast was excellent with a selection including omelet bar . I strongly recommend staying at this great resort. "
The price is AED 465
AED 512 total
includes taxes & fees
3 May - 4 May
Residence Inn by Marriott Panama City
Courtyard by Marriott Panama Multiplaza Mall
Lounge

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1023)
"The staff service was excellent."
The price is AED 493
AED 542 total
includes taxes & fees
18 Apr - 19 Apr
Courtyard by Marriott Panama Multiplaza Mall
Plaza Paitilla Inn Hotel
View from property

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2053)
"I have no complaints about my stay, everything was nice and I enjoyed the breakfasr"
The price is AED 346
AED 381 total
includes taxes & fees
3 Apr - 4 Apr
Plaza Paitilla Inn Hotel
Las Americas Golden Tower Panama
Interior entrance

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1069)
"Central location "
The price is AED 560
AED 617 total
includes taxes & fees
6 Apr - 7 Apr
Las Americas Golden Tower Panama
Decapolis Hotel Panama City
Exterior

Decapolis Hotel Panama City

4.0 star property
8.4 out of 10, Very Good, (1208)
"It is a very nice property and if one considers the price it’s even better. A very nice hotel! It has a shopping center and casino (if so inclined) as part of the property. "
The price is AED 310
AED 341 total
includes taxes & fees
3 Apr - 4 Apr
Decapolis Hotel Panama City
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (825)
"10/10"
The price is AED 467
AED 513 total
includes taxes & fees
3 Apr - 4 Apr
Megapolis Hotel Panamá
Nomada Container Hotel Panama City
Coffee shop

Nomada Container Hotel Panama City

3.0 star property
8.8 out of 10, Excellent, (132)
"Hotel was fine. Property does not communicate at all. After I booked, I emailed asking for an early check-in. It would have been fine if they just said no, but they never replied. Then when I arrived I asked if I could get in a bit early again. There were no other guests at the property and they still didn't get me an early check in. "
The price is AED 245
AED 269 total
includes taxes & fees
30 Apr - 1 May
Nomada Container Hotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Ana
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is a highly ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 97 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.