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Find hotels in Santa Ana, Panama City from AED 204

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Discover 1,315 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3450)
"Love the breakfast "
The price is AED 422
AED 465 total
includes taxes & fees
28 Jan - 29 January 2025
Hotel Riu Plaza Panama
JW Marriott Panama
View from property

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"Great staff, beautiful pool and view "
The price is AED 804
AED 885 total
includes taxes & fees
31 Jan - 1 February 2025
JW Marriott Panama
Plaza Paitilla Inn Hotel
Room

Plaza Paitilla Inn Hotel

3.5 star property
9.2 out of 10, Wonderful, (1740)
"The good: staff were mostly friendly, and the breakfast was amazing! The bad: our first room- the door handle broke off. They moved us. Second room:gross. The hand towel had a giant yellow booger smeared on it, there was poo down the front of the toilet, and lipstick stains on the wall. "
The price is AED 329
AED 362 total
includes taxes & fees
13 Jan - 14 January 2025
Plaza Paitilla Inn Hotel
Decapolis Hotel Panama City
Front of property

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1007)
"The easy way to be in a hotel and suddenly you are in the mall. Great short cut."
The price is AED 300
AED 330 total
includes taxes & fees
17 Jan - 18 January 2025
Decapolis Hotel Panama City
W Panama
Exterior

W Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"It’s a nice hotel, rooms are great and the price very reasonable. But the area around is not very nice and it may be more of a business hotel than a tourist one. I would stay in the old town if I came back. More to walk to and nicer surroundings. But this hotel was nice for what it is. "
The price is AED 658
AED 724 total
includes taxes & fees
11 Jan - 12 January 2025
W Panama
Waldorf Astoria Panama
Room

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1000)
"beautiful hotel. friendly staff. only complaint i have is the mini bar prices were absolutely ridiculous. the snack prices were insane. "
The price is AED 590
AED 649 total
includes taxes & fees
8 Jan - 9 January 2025
Waldorf Astoria Panama
Hilton Panama
Room

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1000)
"Great location and very professional staff and great service "
The price is AED 621
AED 683 total
includes taxes & fees
24 Jan - 25 January 2025
Hilton Panama
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (727)
"Quite nice"
The price is AED 525
AED 578 total
includes taxes & fees
22 Jan - 23 January 2025
Megapolis Hotel Panamá
Novotel Panama City
Exterior

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1001)
"Ideal location in panama city around plenty of attractions plus travel package offered by hotel"
The price is AED 331
AED 364 total
includes taxes & fees
9 Jan - 10 January 2025
Novotel Panama City
Ramada Plaza By Wyndham Panama Punta Pacífica
Exterior

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.4 out of 10, Exceptional, (1000)
"Really enjoyed our stay! The staff was SO accommodating, and everything was immaculately clean!"
The price is AED 373
AED 410 total
includes taxes & fees
14 Jan - 15 January 2025
Ramada Plaza By Wyndham Panama Punta Pacífica
Hospedium Princess Hotel Panama
Pool

Hospedium Princess Hotel Panama

3.5 star property
7.8 out of 10, Good, (372)
"very good"
The price is AED 204
AED 224 total
includes taxes & fees
17 Jan - 18 January 2025
Hospedium Princess Hotel Panama
Principe Hotel and Suites
Front of property - evening/night

Principe Hotel and Suites

3.0 star property
8.8 out of 10, Excellent, (1161)
"Was great"
The price is AED 263
AED 289 total
includes taxes & fees
9 Jan - 10 January 2025
Principe Hotel and Suites
Waymore Hotel Spa & Casino
Exterior

Waymore Hotel Spa & Casino

4.0 star property
9.0 out of 10, Wonderful, (136)
"Excellent !!! Reception were attentive to all my needs and offered great customer service. Will return soon Thank you"
The price is AED 347
AED 422 total
includes taxes & fees
8 Jan - 9 January 2025
Waymore Hotel Spa & Casino
Riande Urban Hotel
Outdoor pool

Riande Urban Hotel

3.5 star property
8.6 out of 10, Excellent, (1008)
"Hotel was rather difficult to locate especially at night. We didn’t see any hotel sign and actually drove past the hotel a few times. We finally found it after asking around. Area surrounding the hotel was dark. Hotel itself was pleasant. People working at the front desk and hotel were very helpful. Would still recommend this hotel!"
The price is AED 253
AED 278 total
includes taxes & fees
5 Jan - 6 January 2025
Riande Urban Hotel
Sofitel Legend Casco Viejo, Panama City
Exterior detail

Sofitel Legend Casco Viejo, Panama City

5.0 star property
10.0 out of 10, Exceptional, (364)
"Simply amazing service on a world class level!"
The price is AED 1,421
AED 1,564 total
includes taxes & fees
8 Jan - 9 January 2025
Sofitel Legend Casco Viejo, Panama City
Summit Rainforest & Golf Resort
Aerial view

Summit Rainforest & Golf Resort

4.0 star property
8.4 out of 10, Very Good, (1007)
"Beautiful clean resort. "
The price is AED 301
AED 338 total
includes taxes & fees
2 Jan - 3 January 2025
Summit Rainforest & Golf Resort
Las Americas Golden Tower Panama
Room

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1008)
"Excellent service, great location "
The price is AED 627
AED 690 total
includes taxes & fees
14 Jan - 15 January 2025
Las Americas Golden Tower Panama
Central Hotel Panama Casco Viejo
Rooftop pool

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (782)
"Very old hotel from 1879. But it is well maintained and super comfortable. It is in a great location. Zero complaints. If I return to Panama City I will stay here."
The price is AED 1,024
AED 1,127 total
includes taxes & fees
31 Jan - 1 February 2025
Central Hotel Panama Casco Viejo
Marriott Panama Hotel
Porch

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Wonderful property...great location for shopping....excellent staff!!!"
The price is AED 526
AED 578 total
includes taxes & fees
3 Jan - 4 January 2025
Marriott Panama Hotel
Bristol Panama, a Registry Collection Hotel
Exterior

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1003)
"Beautiful property. Wonderful restaurant with delicious food. The spa was superb."
The price is AED 519
AED 571 total
includes taxes & fees
11 Jan - 12 January 2025
Bristol Panama, a Registry Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is a highly ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 96 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.