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Find hotels in Santa Ana, Panama City from AED 242

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Discover 1,328 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (3303)
"Everything was good."
The price is AED 386
AED 424 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Riu Plaza Panama
JW Marriott Panama
Pool
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Would visit again"
The price is AED 555
AED 601 total
includes taxes & fees
7 Dec - 8 Dec
JW Marriott Panama
Decapolis Hotel Panama City
Front of property
Decapolis Hotel Panama City
4.0 star property
8.6 out of 10, Excellent, (1003)
"location"
The price is AED 295
AED 325 total
includes taxes & fees
10 Dec - 11 Dec
Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel
Room
Plaza Paitilla Inn Hotel
3.5 star property
9.2 out of 10, Wonderful, (1677)
"Poor Internet "
The price is AED 367
AED 404 total
includes taxes & fees
5 Dec - 6 Dec
Plaza Paitilla Inn Hotel
Waldorf Astoria Panama
Room
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (997)
"My hubby and i stayed during our 16 yr anniversary. The staff was very helpful in every way. William in the restaurant made our stay even more comfortable and enjoyable because he spoke English and was such a excellent host greeting us everyday and giving us his best recommendations. Thank you so much William. You are the best!"
The price is AED 555
AED 611 total
includes taxes & fees
7 Dec - 8 Dec
Waldorf Astoria Panama
Megapolis Hotel Panamá
Front of property
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very Good, (690)
"Breakfast was good. Staff very helpful. Megapolis mall was somewhat empty. Not a lot of stores operating. However the Multiplaza Mall nearby was excellent. "
The price is AED 441
AED 485 total
includes taxes & fees
24 Nov - 25 Nov
Megapolis Hotel Panamá
Novotel Panama City
Exterior
Novotel Panama City
4.0 star property
9.0 out of 10, Wonderful, (1005)
"For people on business trip"
The price is AED 331
AED 364 total
includes taxes & fees
1 Dec - 2 Dec
Novotel Panama City
Principe Hotel and Suites
Front of property - evening/night
Principe Hotel and Suites
3.0 star property
8.8 out of 10, Excellent, (1140)
"Rooms were fine. Clean. Toilet clogging situation but resolved. Noisy hallways throughout the night. "
The price is AED 263
AED 289 total
includes taxes & fees
25 Nov - 26 Nov
Principe Hotel and Suites
W Panama
Exterior
W Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Lo único que puedo decir es que el baño mejor la ducha tiene moho. Todo lo demás estuvo muy lindo y bueno"
The price is AED 467
AED 506 total
includes taxes & fees
13 Dec - 14 Dec
W Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Exterior
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1003)
"Really nice place to stay…walking distance to malls restaurants and a casino…"
The price is AED 411
AED 453 total
includes taxes & fees
28 Nov - 29 Nov
Ramada Plaza By Wyndham Panama Punta Pacífica
Hilton Panama
Room
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1003)
"The hotel was modern and well maintained. Staff were friendly and helpful. Loved how central it was and close to everything."
The price is AED 505
AED 556 total
includes taxes & fees
13 Dec - 14 Dec
Hilton Panama
Riande Urban Hotel
Outdoor pool
Riande Urban Hotel
3.5 star property
8.6 out of 10, Excellent, (1007)
"A nice small hotel with a nice pool a quiet rooms. Had a cool bar to chill and watch a game after a long work day. Will definitely be staying there again for business trips. "
The price is AED 253
AED 278 total
includes taxes & fees
25 Nov - 26 Nov
Riande Urban Hotel
Hospedium Princess Hotel Panama
Pool
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (347)
"Our stay at the Hospedium exceeded our expectations. Would definitely go back! We enjoyed it breakfast buffet every morning. "
The price is AED 242
AED 266 total
includes taxes & fees
28 Nov - 29 Nov
Hospedium Princess Hotel Panama
Waymore Hotel Spa & Casino
Exterior
Waymore Hotel Spa & Casino
4.0 star property
9.0 out of 10, Wonderful, (115)
"Our overall experience here was quite great. The pool was always very clean with plenty of spots to lounge. They’ll even bring you drinks (the caipirinhas were fantastic). Great gym with a full bench press/incline bench, treadmills, machines for essentially anything you need. The restaurant was pretty good as well. The only part that gave our stay a star less were the alarms that went off on our floor various times through our stay. Doubt this was the fault of the hotel (likely other guests) but...
The price is AED 347
AED 382 total
includes taxes & fees
23 Nov - 24 Nov
Waymore Hotel Spa & Casino
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Exterior
Holiday Inn Panama Distrito Financiero, an IHG Hotel
4.0 star property
8.8 out of 10, Excellent, (1008)
"Location was safe and clean and near shopping areas for my daughter's birthday visit. "
The price is AED 320
AED 352 total
includes taxes & fees
8 Dec - 9 Dec
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Sofitel Legend Casco Viejo, Panama City
Exterior detail
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (337)
"Very clean and the staff was very friendly and helpful always checking to see how they could improve my wonderful experience "
The price is AED 1,074
AED 1,182 total
includes taxes & fees
19 Dec - 20 Dec
Sofitel Legend Casco Viejo, Panama City
MARINN PLACE Financial District
Room
MARINN PLACE Financial District
3.5 star property
9.0 out of 10, Wonderful, (138)
"Great location, easy access. Only three things didnt fit right. There where only two tissues left in the box in The bathroom, they should have been changed. During breakfast, they had good options, but bacon was missing, The rotating door at the entrance does not work."
The price is AED 312
AED 344 total
includes taxes & fees
24 Nov - 25 Nov
MARINN PLACE Financial District
Marriott Panama Hotel
Pool
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"I really enjoyed my time at the Marriott and im looking forward to coming back soon "
The price is AED 529
AED 573 total
includes taxes & fees
21 Dec - 22 Dec
Marriott Panama Hotel
Las Americas Golden Tower Panama
Room
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, (1000)
"Hotel was okay, a bit outdated but good location. "
The price is AED 489
AED 538 total
includes taxes & fees
14 Dec - 15 Dec
Las Americas Golden Tower Panama
Bristol Panama, a Registry Collection Hotel
Room
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"It is a great hotel, with great staff and superb personalized service. Totally recommended!"
The price is AED 624
AED 687 total
includes taxes & fees
21 Dec - 22 Dec
Bristol Panama, a Registry Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is a highly ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 113 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.