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Find 5 Star Hotels in Santa Ana from AED 310

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Check availability on Santa Ana 5 Star Hotels

Tonight
31 Mar - 1 Apr
Tomorrow
1 Apr - 2 Apr
This weekend
4 Apr - 6 Apr
Next weekend
11 Apr - 13 Apr

Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4086)
"We enjoy our stay I will recommend it"
The price is AED 422
AED 465 total
includes taxes & fees
29 Apr - 30 Apr
Hotel Riu Plaza Panama
W Panama
Marvelous Suite, Suite, 1 King Bed, Non Smoking, City View | In-room safe, blackout drapes, iron/ironing board

W Panama

5.0 star property
8.8 out of 10, Excellent, (1135)
"Amazinggg place ! Def would book again"
The price is AED 673
AED 740 total
includes taxes & fees
1 May - 2 May
W Panama
Waldorf Astoria Panama
Outdoor pool, pool umbrellas, sun loungers

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1061)
"Excellent location and easy access to restaurants, shopping and sea wall. Hotel staff were always friendly and eager to assist."
The price is AED 809
AED 889 total
includes taxes & fees
13 Apr - 14 Apr
Waldorf Astoria Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1161)
"Love the staff"
The price is AED 1,098
AED 1,208 total
includes taxes & fees
26 Apr - 27 Apr
JW Marriott Panama
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, steam room, Turkish bath, body treatments

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1108)
"Only place I stay "
The price is AED 578
AED 635 total
includes taxes & fees
1 May - 2 May
Bristol Panama, a Registry Collection Hotel
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (419)
"It’s a beautiful hotel and the service is exceptional. The pool area and the views are very special. I would also like to commend some of the staff who were most helpful and friendly during my stay. Julissa in room service was very friendly and genuinely committed to her guests, a smiling face to greet me each morning. Jesus at the front desk and Shaun both went above and beyond to help answer my questions and replace a lost key. The staff represent the hotel and the warm and friendly country of...
The price is AED 1,074
AED 1,182 total
includes taxes & fees
21 Apr - 22 Apr
Sofitel Legend Casco Viejo, Panama City
The Westin Playa Bonita Panama
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1098)
"Location was great. Easy 45 minute ride from the international airport and less than that to local attractions. Food was great at the hotel and always had plenty of options for adults and children. Note: We had the premium package and would recommend. Kudos to the staff for keeping the property, rooms and pools clean at this large facility. "
The price is AED 720
AED 792 total
includes taxes & fees
1 May - 2 May
The Westin Playa Bonita Panama
Hilton Panama
Outdoor pool

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1129)
"This was a very nice property and location. Next time I would stay in Casco Viejo because everything was there. This was a great location as well especially if you’re looking for a quieter area."
The price is AED 782
AED 860 total
includes taxes & fees
12 Apr - 13 Apr
Hilton Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (554)
"Awesome everything "
The price is AED 780
AED 858 total
includes taxes & fees
18 Apr - 19 Apr
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Renaissance Panama City Hotel
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

5.0 star property
7.6 out of 10, Good, (864)
"Nightlife"
The price is AED 437
AED 481 total
includes taxes & fees
11 Apr - 12 Apr
Renaissance Panama City Hotel
Veneto Hotel & Casino
Outdoor pool

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (998)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Ana.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is AED 397 per night from Apr 25 to Apr 26
AED 397
AED 497 total
includes taxes & fees
25 Apr - 26 Apr
8.4/10 Very Good! (2,092 reviews)
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Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from AED 310

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.
Are there any 5-star all-inclusive resorts in Santa Ana?
Expedia’s filter tool is the best way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to show the most luxurious hotels in Santa Ana where your meals, room, entertainment and activities are included in the upfront price. At these getaways, your trip is pure leisure from the moment you put down your suitcase.
What are the top 5-star spa hotels in Santa Ana?
If you’re looking for some TLC, you can’t beat W Panama. Other 5-star spa properties that are renowned for their rejuvenating treatments are Hilton Panama and Waldorf Astoria Panama, also found in or around Santa Ana.
Are there any 5-star vacation rentals in Santa Ana?
Although there aren’t any 5-star vacation rentals in Santa Ana on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your needs by searching our vacation rentals in Santa Ana.