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Find 5 Star Hotels in Santa Ana from AED 300

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Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3440)
"The hotel is very nice but at this point in time very dated. The outlets in the room were a little bit loose so nothing that you plugged in would stay in the room definitely could use a refresh. And the hotel is working in a safe area but it’s not walkable to anything. There are no restaurants or nighttime activities. But an Uber the most parts of the city is less than $5 USD . Not bad"
The price is AED 437
AED 481 total
includes taxes & fees
6 Jan - 7 January 2025
Hotel Riu Plaza Panama

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1004)
"Great Stay, staff was very friendly! Rooms were very nice and clean."
The price is AED 621
AED 683 total
includes taxes & fees
10 Jan - 11 January 2025
Waldorf Astoria Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1008)
"Amazing staff. Maria at the front desk was very helpful. The breakfast was good with variety of options. The surrounding areas was kinda of off, with several construction sites."
The price is AED 768
AED 844 total
includes taxes & fees
11 Jan - 12 January 2025
JW Marriott Panama

W Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"The property and room was amazing!!! The staff were very friendly and helpful. "
The price is AED 592
AED 651 total
includes taxes & fees
11 Jan - 12 January 2025
W Panama

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1002)
"Property was nice. People were friendly. Didn’t care for any of the food at the restaurants so I opted not to get the all inclusive option. Pools close at 7pm. They are very clean though. The worst part is that o stayed on the six floor and there was this disgusting smell each day at certain times of the day in the hall and also on the room. Eventually I would become nose blind to it but it was heinous. Very relaxing g property though. "
The price is AED 740
AED 814 total
includes taxes & fees
19 Jan - 20 January 2025
The Westin Playa Bonita Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"Great location and very professional staff and great service "
The price is AED 621
AED 683 total
includes taxes & fees
10 Jan - 11 January 2025
Hilton Panama

Sofitel Legend Casco Viejo, Panama City

5.0 star property
10.0 out of 10, Exceptional, (361)
"El hotel es hermoso. Tiene muchos detalles. El diseño y la arquitectura. La ubicación. Es como en las fotos. La gente muy servicial. Puedes pedir cualquier comida de la carta las 24 horas del día y te lo llevan a la habitación. Nuestra habitación tenía un balcón bello en donde nos colocaron una mesa rodante de donde venía la comida que ordenamos. Muy especial. La cama y almohadas muy cómodas. Estilo colonial hermoso! "
The price is AED 1,355
AED 1,491 total
includes taxes & fees
7 Jan - 8 January 2025
Sofitel Legend Casco Viejo, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (523)
"A very classy and chic Hotel that exceeded my expectations. The customer service and customer care are exceptional. Andrea, who works at the front desk, was so helpful and accommodating to us. The rooms are bright, big and very clean. Lobby area is very nicely decorated. Breakfast was amazing, there was nothing you could not find there. "
The price is AED 768
AED 844 total
includes taxes & fees
24 Jan - 25 January 2025
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1002)
"Beautiful property. Wonderful restaurant with delicious food. The spa was superb."
The price is AED 574
AED 632 total
includes taxes & fees
19 Jan - 20 January 2025
Bristol Panama, a Registry Collection Hotel

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (997)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from AED 300

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.
Are there any 5-star all-inclusive resorts in Santa Ana?
Expedia’s filter tool is the best way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to show the most luxurious hotels in Santa Ana where your meals, room, entertainment and activities are included in the upfront price. At these getaways, your trip is pure leisure from the moment you put down your suitcase.
What are the top 5-star spa hotels in Santa Ana?
If you’re looking for some TLC, you can’t beat W Panama. Other 5-star spa properties that are renowned for their rejuvenating treatments are Hilton Panama and Waldorf Astoria Panama, also found in or around Santa Ana.
Are there any 5-star vacation rentals in Santa Ana?
Although there aren’t any 5-star vacation rentals in Santa Ana on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your needs by searching our vacation rentals in Santa Ana.