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Find 5 Star Hotels in Santa Ana from AED 341

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Check availability on Santa Ana 5 Star Hotels

Tonight
25 Apr - 26 Apr
Tomorrow
26 Apr - 27 Apr
This weekend
25 Apr - 27 Apr
Next weekend
2 May - 4 May

Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3854)
"I loved everything about the hotel. They offer breakfast and two bottles of water for the room."
The price is AED 459
AED 505 total
includes taxes & fees
29 Apr - 30 Apr
Hotel Riu Plaza Panama
W Panama
Marvelous Suite, Suite, 1 King Bed, Non Smoking, City View | In-room safe, blackout drapes, iron/ironing board

W Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"Unique pool area "
The price is AED 614
AED 676 total
includes taxes & fees
24 May - 25 May
W Panama
Waldorf Astoria Panama
Outdoor pool, pool umbrellas, sun loungers

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1001)
"Great staff!! "
The price is AED 840
AED 924 total
includes taxes & fees
3 May - 4 May
Waldorf Astoria Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1004)
"Perfect "
The price is AED 673
AED 740 total
includes taxes & fees
6 May - 7 May
JW Marriott Panama
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1002)
"Really nice by property but more for business. "
The price is AED 549
AED 604 total
includes taxes & fees
17 May - 18 May
Bristol Panama, a Registry Collection Hotel
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (441)
"Simply Excellent!!!! Wonderful staff and beautiful place!! Loved it!"
The price is AED 1,074
AED 1,182 total
includes taxes & fees
1 May - 2 May
Sofitel Legend Casco Viejo, Panama City
The Westin Playa Bonita Panama
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1000)
"We loved our time staying at this beautiful resort. Everyone was so nice and welcoming. The service was fantastic. Beautiful and close to everything. I would recommend it to anyone!"
The price is AED 599
AED 659 total
includes taxes & fees
6 May - 7 May
The Westin Playa Bonita Panama
Hilton Panama
Outdoor pool

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1004)
"Outstanding hotel, food and services."
The price is AED 679
AED 747 total
includes taxes & fees
16 May - 17 May
Hilton Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (566)
"By far One of the best hotels in Panama ! "
The price is AED 810
AED 891 total
includes taxes & fees
23 May - 24 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Renaissance Panama City Hotel
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

5.0 star property
8.6 out of 10, Excellent, (13)
"Nightlife"
The price is AED 466
AED 513 total
includes taxes & fees
9 May - 10 May
Renaissance Panama City Hotel
Veneto Hotel & Casino
Outdoor pool

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (998)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Ana.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is AED 437 per night from May 5 to May 6
AED 437
AED 481 total
includes taxes & fees
5 May - 6 May
8.4/10 Very Good! (2,104 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from AED 341

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.
Are there any 5-star all-inclusive resorts in Santa Ana?
Expedia’s filter tool is the best way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to show the most luxurious hotels in Santa Ana where your meals, room, entertainment and activities are included in the upfront price. At these getaways, your trip is pure leisure from the moment you put down your suitcase.
What are the top 5-star spa hotels in Santa Ana?
If you’re looking for some TLC, you can’t beat W Panama. Other 5-star spa properties that are renowned for their rejuvenating treatments are Hilton Panama and Waldorf Astoria Panama, also found in or around Santa Ana.
Are there any 5-star vacation rentals in Santa Ana?
Although there aren’t any 5-star vacation rentals in Santa Ana on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your needs by searching our vacation rentals in Santa Ana.