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Popular places to visit

River Walk
River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the great live music and shops in this walkable area.

Six Flags Fiesta Texas
Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the entertainment choices and lively festivals in this family-friendly area.

Lackland Air Force Base
Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area.

Alamo
Alamo is a top museum in San Antonio with a rich history. Experience the acclaimed theater scene and great live music in this walkable area.

San Antonio Zoo and Aquarium
Why not visit the animals who live at San Antonio Zoo and Aquarium and see why this is a favorite attraction in San Antonio? Experience the acclaimed theater scene and lively festivals in this walkable area.

Alamodome
Catch an event at Alamodome during your trip to San Antonio. Experience the acclaimed theater scene and great live music in this walkable area.
Medical Center District Hotel Deals

Reviewed on 14 April 2025

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Other neighborhoods around Medical Center District

Northwest Los Angeles Heights
If you're looking for some top things to see and do in Northwest Los Angeles Heights and surrounding area, you can visit San Antonio Zoo and Aquarium and San Antonio River.

Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Tobin Hill
If you're spending some time in Tobin Hill, San Antonio River and Temple Beth-El are top sights worth seeing.

Uptown
While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and San Antonio River.
- Places of interest
- Medical Center District Hotels by Star Rating
- Hotels in top San Antonio neighborhoods
- Medical Center District Hotels by Brand
- USAA Corporate Office Headquarters
- South Texas Medical Center
- University of Texas Health and Science Center at San Antonio
- CHRISTUS Santa Rosa Hospital - Medical Center
- Oak Hills Country Club
- The San Antonio Art Institute
- River Walk
- Six Flags Fiesta Texas
- Lackland Air Force Base
- Alamo
- Henry B. González Convention Center
- San Antonio Zoo and Aquarium
- San Antonio River
- Alamodome
- The Shops of La Cantera
- Frost Bank Center
- The Rim Shopping Center
- Lackland Air Force Base Visitor Center
- Market Square
- Natural Bridge Caverns
- University of Texas at San Antonio
- Shops at Rivercenter
- North Star Mall
- La Cantera Golf Club