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Find hotels in Uptown, San Antonio from AED 182

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Discover 6,089 Uptown hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham Garden San Antonio Airport

3.0 star property
Uptown
9.4 out of 10, Exceptional, (1002)
"The staff was amazing ! The kickbacks and free drinks every night we stayed were delish ! I will definitely stay there again :) "
United States
bertha
The price is AED 347
AED 410 total
includes taxes & fees
7 Dec - 8 Dec
Wyndham Garden San Antonio Airport

Best Western Garden Inn

2.5 star property
Uptown
8.2 out of 10, Very Good, (1002)
"Clean room, friendly and helpful staff."
United States
Robyn
The price is AED 218
AED 255 total
includes taxes & fees
30 Dec - 31 Dec
Best Western Garden Inn

Drury Plaza Hotel San Antonio Airport

3.0 star property
Uptown
9.4 out of 10, Exceptional, (1934)
"Great hotel in the center of everything. Loved all the food benefits and felt safe, nice parking too!"
United States
Ashley
The price is AED 331
AED 391 total
includes taxes & fees
1 Jan - 2 January 2026
Drury Plaza Hotel San Antonio Airport

Hampton Inn & Suites San Antonio-Airport

2.5 star property
Uptown
8.4 out of 10, Very Good, (1734)
"I had a great stay "
United States
Carol
The price is AED 291
AED 345 total
includes taxes & fees
18 Dec - 19 Dec
Hampton Inn & Suites San Antonio-Airport

La Quinta Inn & Suites by Wyndham San Antonio Airport

3.0 star property
Uptown
7.8 out of 10, Good, (2843)
"Courteous staff , clean bed & bathrooms"
United States
Ralph
The price is AED 276
AED 326 total
includes taxes & fees
18 Dec - 19 Dec
La Quinta Inn & Suites by Wyndham San Antonio Airport

Crowne Plaza San Antonio Airport by IHG

3.5 star property
Uptown
8.4 out of 10, Very Good, (1483)
"Nice courteous staff, clean room"
United States
Tina
The price is AED 262
AED 309 total
includes taxes & fees
7 Dec - 8 Dec
Crowne Plaza San Antonio Airport by IHG

Red Roof Inn San Antonio - Airport

2.0 star property
Uptown
8.2 out of 10, Very Good, (1107)
"Staff was so friendly "
United States
Shqiprim
The price is AED 169
AED 199 total
includes taxes & fees
9 Dec - 10 Dec
Red Roof Inn San Antonio - Airport

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 star property
Uptown
9.4 out of 10, Exceptional, (1498)
"Rooms were clean and staff was great."
United States
Victoria
The price is AED 290
AED 343 total
includes taxes & fees
7 Dec - 8 Dec
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Homewood Suites by Hilton San Antonio Airport

3.0 star property
Uptown
8.6 out of 10, Excellent, (1001)
"Great stay"
United States
Meredith
The price is AED 379
AED 450 total
includes taxes & fees
10 Dec - 11 Dec
Homewood Suites by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport

2.0 star property
Uptown
8.6 out of 10, Excellent, (1007)
"Great time staying at this location."
United States
Amy
The price is AED 235
AED 279 total
includes taxes & fees
22 Dec - 23 Dec
Spark by Hilton San Antonio Airport

Comfort Suites San Antonio North - Stone Oak

2.5 star property
Uptown
8.6 out of 10, Excellent, (1000)
"Excellent stay, great place highly recommended "
United States
Cesar
The price is AED 278
AED 324 total
includes taxes & fees
8 Dec - 9 Dec
Comfort Suites San Antonio North - Stone Oak

Embassy Suites by Hilton San Antonio Airport

3.5 star property
Uptown
9.0 out of 10, Wonderful, (1070)
"Great stay!"
United States
darryl
The price is AED 438
AED 518 total
includes taxes & fees
4 Jan - 5 January 2026
Embassy Suites by Hilton San Antonio Airport

SureStay Plus Hotel by Best Western San Antonio North

2.5 star property
Uptown
7.0 out of 10, Good, (1000)
"The staff members were very helpful and friendly, my room was clean and check-in was a smooth process "
United States
Reginald
The price is AED 184
AED 214 total
includes taxes & fees
5 Dec - 6 Dec
SureStay Plus Hotel by Best Western San Antonio North

Days Inn by Wyndham San Antonio Airport

2.0 star property
Uptown
8.2 out of 10, Very Good, (1002)
"Great place to lie your head right close to the airport "
Canada
Kevin
The price is AED 192
AED 224 total
includes taxes & fees
18 Dec - 19 Dec
Days Inn by Wyndham San Antonio Airport

Holiday Inn Express San Antonio-Airport by IHG

2.5 star property
Uptown
9.4 out of 10, Exceptional, (1020)
"Great place. Clean and friendly staff."
Mexico
Jose
The price is AED 320
AED 379 total
includes taxes & fees
20 Dec - 21 Dec
Holiday Inn Express San Antonio-Airport by IHG

Home2 Suites by Hilton San Antonio Airport, TX

3.0 star property
Uptown
8.6 out of 10, Excellent, (1010)
"Very good stay "
United States
Roberto
The price is AED 320
AED 379 total
includes taxes & fees
14 Dec - 15 Dec
Home2 Suites by Hilton San Antonio Airport, TX

Super 8 by Wyndham San Antonio Airport North

2.5 star property
Uptown
7.4 out of 10, Good, (1000)
"Staff is excellent. "
United States
Sabrena
The price is AED 215
AED 252 total
includes taxes & fees
18 Dec - 19 Dec
Super 8 by Wyndham San Antonio Airport North

Hilton Garden Inn San Antonio Airport South

3.0 star property
Uptown
8.4 out of 10, Very Good, (1001)
"Friendly Staff and Clean Room"
United States
Patrick
The price is AED 280
AED 337 total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn San Antonio Airport South

Baymont by Wyndham San Antonio Airport

2.0 star property
Uptown
6.2 out of 10, (888)
"Stay was quiet and peaceful. Nice and courteous staff"
United States
Jennifer
The price is AED 156
AED 182 total
includes taxes & fees
1 Jan - 2 January 2026
Baymont by Wyndham San Antonio Airport

Courtyard by Marriott San Antonio Airport

3.0 star property
Uptown
8.4 out of 10, Very Good, (1000)
"Very friendly and courteous staff, great breakfast."
United States
Viju
The price is AED 340
AED 402 total
includes taxes & fees
13 Dec - 14 Dec
Courtyard by Marriott San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Top Uptown Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Uptown?
Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighborhood has to offer. Are you looking for Uptown travel tips? Be sure to check out Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighborhood.
What's the best accommodation in Uptown?
Based on Expedia customer reviews, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is the highest ranked property in Uptown. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Wyndham Garden San Antonio Airport and Drury Plaza Hotel San Antonio Airport.
How many hotels will I be able to find in the Uptown area?
Expedia has 373 hotels and other accommodations in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Uptown.
Where can I learn more about changing or cancelling my trip to Uptown?
To find more details about picking new dates or cancelling your trip to Uptown, click here.
What can I see and do in this San Antonio neighborhood?
Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum, and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighborhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club, and Regal Alamo Quarry. McDermott Center and UIW Tennis Center are also worth a visit when you're out sightseeing in San Antonio.