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Check prices for these dates

Next weekend
4 Apr - 6 Apr
In two weeks
11 Apr - 13 Apr
In one month
25 Apr - 27 Apr
In two months
23 May - 25 May

Compare 141 Vacation Homes in O Brien with updated reviews, rates, and availability.

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock
Miscellaneous

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

9.8 out of 10, Exceptional, (201)
"A beautiful place to take the family to disconnect the electronics and reconnect with each other. It was our first time in the ichetucknee and it was magic. Highly recommend exploring this area from the comfort of this cabin. "
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock
Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs
Property grounds

Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs

10.0 out of 10, Exceptional, (8)
"Perfect spot, clean, well stocked. Thoroughly enjoyed our stay! "
Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee
Pool

The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

10.0 out of 10, Exceptional, (57)
"I've always enjoyed staying here. This stay was great. The communication was easy and they were very responsive. I noticed several upgrades and the home looks and feels great. I was happy to see the home survived the brutal storms last year relatively unscathed. It was a very cozy stay with all that we needed. Thank you. "
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee
Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️
Terrace/patio

Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

9.8 out of 10, Exceptional, (27)
"Relatives from PA were camping at O’Leno State Park. Spent some time touring and visiting with them."
The price is AED 397
AED 1,028 total
includes taxes & fees
1 Apr - 2 Apr
Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️
Bunkhouse Farm Stay
Fridge, microwave, oven, stovetop

Bunkhouse Farm Stay

10.0 out of 10, Exceptional, (128)
"Stayed for a long weekend with my son for the NHRA in Gainesville. We’re FL locals but this was a great change of pace from the city. Not far from I75 to get you to and from places but far enough away at the same time. The Bunk House is by itself away from the main houses on the property so it was very private. It’s an old converted place but upon entering, you get the whole vibe in a VERY clean and well decorated quaint place. Smells nice, and the character was charming. Don’t hesitate to book...
Bunkhouse Farm Stay
The Cozy Retreat
Private kitchen

The Cozy Retreat

10.0 out of 10, Exceptional, (1)
"Overall amazing"
The Cozy Retreat
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
Miscellaneous

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

9.8 out of 10, Exceptional, (82)
"Location is perfect for our planned activities."
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
Secluded and very unique OFF grid country home, 15 springs within an hour.
Property grounds

Secluded and very unique OFF grid country home, 15 springs within an hour.

10.0 out of 10, Exceptional, (5)
"We had an amazing time at the property and the parks near by. The house itself is very unique and is very spacious. The bedrooms were all very clean, good size and comfy beds. The living room was a nice spot for the family to hangout together and watch a movie on the large tv. Kitchen was well stocked and had a really cool seating area for the family to enjoy a meal together. The porch/patio area was the spot to be in. It was a Perfect area for hanging out, playing pool and pingpong. The...
Secluded and very unique OFF grid country home, 15 springs within an hour.
Pet-Friendly Florida Escape w/ Patio & Fire Pit!
Fridge, microwave, stovetop, dishwasher

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

10.0 out of 10, Exceptional, (17)
"I was so impressed with this cute house! It was all labeled so you knew where everything was. They also provided plenty of clean towels so you didn’t have to do anything as every day. My daughter got engaged at the state park on St. Patrick day! This house was so close by for all of us! The beds were very comfortable and they had plenty of extra blankets . We will definitely save this house for our next trip! Thank you Bill "
Pet-Friendly Florida Escape w/ Patio & Fire Pit!
Modern & Convenient 3/2 Home
Private kitchen

Modern & Convenient 3/2 Home

10.0 out of 10, Exceptional, (10)
"Very nice kitchen "
Modern & Convenient 3/2 Home
Quaint rural downtown community close to springs, 3 rivers, biking & equestrian
Onsite parking

Quaint rural downtown community close to springs, 3 rivers, biking & equestrian

9.2 out of 10, Wonderful, (39)
"Everything is listing was accurate. Was perfect for our reason for visiting"
Quaint rural downtown community close to springs, 3 rivers, biking & equestrian
Serene at the Springs - New Reno & Tesla Charger
Fridge, microwave, oven, stovetop

Serene at the Springs - New Reno & Tesla Charger

10.0 out of 10, Exceptional, (6)
"Clean, nicely decorated, nice screen porch out back with a TV, comfortable beds. Would stay again."
The price is AED 371
AED 970 total
includes taxes & fees
1 Apr - 2 Apr
Serene at the Springs - New Reno & Tesla Charger
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Pool

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

10.0 out of 10, Exceptional, (39)
"We stayed here on the way to Disney. Perfect quiet location to rest after a long drive. "
The price is AED 547
AED 1,019 total
includes taxes & fees
7 Apr - 8 Apr
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Custom Built Home steps from the Santa Fe River
Outdoor dining

Custom Built Home steps from the Santa Fe River

10.0 out of 10, Exceptional, (68)
"We loved the property. Very comfy. Beautiful view. "
Custom Built Home steps from the Santa Fe River
Peaceful property on the historic Suwannee River.
Property grounds

Peaceful property on the historic Suwannee River.

10.0 out of 10, Exceptional, (21)
"We chose this spot for a Family Christmas celebration based on it’s distance from multiple households (coming from FL & GA). It was perfect for large families to spend quality time together, but also so much space that it provided lots of privacy too. All of the rooms were of generous size- especially the upstairs master! The wrap around porches on both levels were great! Nice to be able to walk out from the master & see everyone by the fire pit or the river down below. It is pretty much in the...
Peaceful property on the historic Suwannee River.
Beautiful New House on 5 Acres close to springs
Aerial view

Beautiful New House on 5 Acres close to springs

10.0 out of 10, Exceptional, (18)
"Hots we’re wonderful and responded so quickly to our emails!"
The price is AED 675
AED 1,430 total
includes taxes & fees
30 Mar - 31 Mar
Beautiful New House on 5 Acres close to springs
Located on the Santa Fe River perfect for boating & tubing on the Ichetucknee.
Property grounds

Located on the Santa Fe River perfect for boating & tubing on the Ichetucknee.

9.8 out of 10, Exceptional, (24)
"Was a fabulous time(except for rain) but we made the best of it and took advantage of staying in a beautiful and comfortable home. Was just our style! Can’t wait to come again!"
Located on the Santa Fe River perfect for boating & tubing on the Ichetucknee.
Hilltop House
Fridge, oven, stovetop, coffee/tea maker

Hilltop House

9.6 out of 10, Exceptional, (13)
"Stayed while visting family over labor day weekend. If you have lifted trucks tree limbs do hang a bit low. Other than that nice and clean place. Super close to springs and overall a great weekend."
Hilltop House
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Aerial view

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

10.0 out of 10, Exceptional, (17)
"Great spot for getting away from it all"
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Serene Live Oak Home w/ Fire Pit by River + SOSMP!
TV

Serene Live Oak Home w/ Fire Pit by River + SOSMP!

8.4 out of 10, Very Good, (7)
"We rented this home to attend the Suwannee Spring Festival with our Florida friends. The home was at a great location to do that and provided us with the quiet restful nights we were looking for during our vacation. We will definitely stay again."
Serene Live Oak Home w/ Fire Pit by River + SOSMP!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in O Brien

Pet-Friendly Florida Escape w/ Patio & Fire Pit!
Fridge, microwave, stovetop, dishwasher

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

10.0 out of 10, Exceptional, (17)
"I was so impressed with this cute house! It was all labeled so you knew where everything was. They also provided plenty of clean towels so you didn’t have to do anything as every day. My daughter got engaged at the state park on St. Patrick day! This house was so close by for all of us! The beds were very comfortable and they had plenty of extra blankets . We will definitely save this house for our next trip! Thank you Bill "
Pet-Friendly Florida Escape w/ Patio & Fire Pit!
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Aerial view

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

10.0 out of 10, Exceptional, (17)
"Great spot for getting away from it all"
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Property grounds

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

9.6 out of 10, Exceptional, (54)
"Very relaxing "
The price is AED 731
AED 1,586 total
includes taxes & fees
8 Apr - 9 Apr
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.