Photo by Dr__Vlad

Search Vacation Homes in O Brien

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Compare 141 Vacation Homes in O Brien with updated reviews, rates, and availability.

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

9.8 out of 10, Exceptional, (207)
"Very Nice that is very private "
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs

10.0 out of 10, Exceptional, (11)
"The house was very clean, nicely decorated and well stocked. We enjoyed the hot tub and the cows across the road. Really close to several springs in the area. We look forward to staying again in the future."
Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs

The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

10.0 out of 10, Exceptional, (58)
"I've always enjoyed staying here. This stay was great. The communication was easy and they were very responsive. I noticed several upgrades and the home looks and feels great. I was happy to see the home survived the brutal storms last year relatively unscathed. It was a very cozy stay with all that we needed. Thank you. "
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

9.8 out of 10, Exceptional, (34)
"Great place, would stay again next time we are in the area. We will definitely stay again."
The price is AED 367
AED 1,002 total
includes taxes & fees
12 May - 13 May
Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

Bunkhouse Farm Stay

10.0 out of 10, Exceptional, (133)
"This is our third year staying here.It's fantastic.Host is very quick to help with any problems.Very quiet and peaceful.I highly recommend this place.You will not be disappointed."
Bunkhouse Farm Stay

The Cozy Retreat

10.0 out of 10, Exceptional, (1)
"Overall amazing"
The Cozy Retreat

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

9.8 out of 10, Exceptional, (86)
"We had a great time - comfortable accommodations and being right on the water was wonderful"
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Secluded and very unique OFF grid country home, 15 springs within an hour.

10.0 out of 10, Exceptional, (6)
"We had a wonderful stay, the house is very accommodating, open floor plan great for large group, outside covered porch was amazing (probably put favorite spot)! Very clean & inviting! Property was fun to explore and felt very safe and secure! Great location, several natural springs to explore within 1 hour drive! Must go to "Deal's Famous Oyster House," and ask for the "pogo stick song!" Overall, definitely give this home a 10/10 rating!"
Secluded and very unique OFF grid country home, 15 springs within an hour.

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

10.0 out of 10, Exceptional, (20)
"Got together with family around the holidays and had a great stay. Place was well stocked with whatever we'd need. Enjoyed yard games in the fenced in backyard while grilling out. Home was clean and beds comfortable. Place was close to where we needed. Highly recommend and would stay here again."
Pet-Friendly Florida Escape w/ Patio & Fire Pit!

Modern & Convenient 3/2 Home

10.0 out of 10, Exceptional, (13)
"Loved the property and neighborhood. The owner was very nice and helpful during the extreme cold spell while we were there. "
Modern & Convenient 3/2 Home

Quaint rural downtown community close to springs, 3 rivers, biking & equestrian

9.0 out of 10, Wonderful, (42)
"We are grateful for a warm stay at the cottage with nearby access to the Spirit of the Suwanee Music Park during a very cold weekend! No snow, but a hard frost. Glad to find a rental that supports a family who has local roots in and care for the area. "
Quaint rural downtown community close to springs, 3 rivers, biking & equestrian

Serene at the Springs - New Reno & Tesla Charger

10.0 out of 10, Exceptional, (10)
"Cute house, very clean, and a great location in a quiet neighborhood with a large, private backyard."
The price is AED 452
AED 1,079 total
includes taxes & fees
18 May - 19 May
Serene at the Springs - New Reno & Tesla Charger

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

10.0 out of 10, Exceptional, (43)
"Love staying at this charming home. It is clean, comfortable with a great patio to enjoy. "
The price is AED 547
AED 1,012 total
includes taxes & fees
9 May - 10 May
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Custom Built Home steps from the Santa Fe River

10.0 out of 10, Exceptional, (69)
"The home was a perfect location to gather with family and enjoy the sights of the river."
Custom Built Home steps from the Santa Fe River

Peaceful property on the historic Suwannee River.

10.0 out of 10, Exceptional, (22)
"This property offers a beautiful view, peaceful atmosphere and plenty of room to spread out. The house was charming, clean and well outfitted for a rental property. I highly recommend relaxing with a coffee on the porch and watching the river go by."
Peaceful property on the historic Suwannee River.

Beautiful New House on 5 Acres close to springs

9.8 out of 10, Exceptional, (19)
"Cute little house with a lot of sleeping choices! It was very easy to find and we enjoyed the quiet area. "
The price is AED 675
AED 1,423 total
includes taxes & fees
11 May - 12 May
Beautiful New House on 5 Acres close to springs

Located on the Santa Fe River perfect for boating & tubing on the Ichetucknee.

9.8 out of 10, Exceptional, (24)
"Our youth church group enjoyed the river and springs while visiting."
Located on the Santa Fe River perfect for boating & tubing on the Ichetucknee.

Hilltop House

9.6 out of 10, Exceptional, (14)
"This place is very close to the springs Very good place to stay"
Hilltop House

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

10.0 out of 10, Exceptional, (18)
"The property was awesome i had a blast i highly recommended "
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Serene Live Oak Home w/ Fire Pit by River + SOSMP!

8.4 out of 10, Very Good, (7)
"House was very clean. Host was flexible about check in time."
Serene Live Oak Home w/ Fire Pit by River + SOSMP!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in O Brien
Save an average of 15% on thousands of hotels when you're signed in

Other property types in O Brien

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

10.0 out of 10, Exceptional, (18)
"The property was awesome i had a blast i highly recommended "
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

10.0 out of 10, Exceptional, (20)
"Got together with family around the holidays and had a great stay. Place was well stocked with whatever we'd need. Enjoyed yard games in the fenced in backyard while grilling out. Home was clean and beds comfortable. Place was close to where we needed. Highly recommend and would stay here again."
Pet-Friendly Florida Escape w/ Patio & Fire Pit!

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

9.6 out of 10, Exceptional, (54)
"Very relaxing "
The price is AED 731
AED 1,575 total
includes taxes & fees
13 May - 14 May
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.