Photo by Dr__Vlad
Find hotels in O Brien, FL from AED 220
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Compare 302 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75
9.6 out of 10, Exceptional, (379)
The price is AED 521
AED 587 total
includes taxes & fees
10 Mar - 11 Mar

Americas Best Value Inn Alachua
Americas Best Value Inn Alachua
4.6 out of 10, (527)
The price is AED 263
AED 296 total
includes taxes & fees
31 Mar - 1 Apr

Royal Inn
Royal Inn
7.2 out of 10, Good, (165)
The price is AED 286
AED 322 total
includes taxes & fees
4 Mar - 5 Mar

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
9.2 out of 10, Wonderful, (1002)
The price is AED 522
AED 587 total
includes taxes & fees
16 Mar - 17 Mar

Vista Verde Farm Retreat
Vista Verde Farm Retreat
The price is AED 567
AED 799 total
includes taxes & fees
18 Mar - 19 Mar

BlueGem Motel
BlueGem Motel
9.2 out of 10, Wonderful, (332)
The price is AED 414
AED 466 total
includes taxes & fees
4 Mar - 5 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about O Brien
Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

Photo by Dr__Vlad
Open Photo by Dr__Vlad
More cheap stays in O Brien
More cheap stays in O Brien

Americas Best Value Inn Lake City
3835 West US Highway 90, Lake City, FL
The price is AED 262 per night from Mar 4 to Mar 5
AED 262
AED 295 total
includes taxes & fees
4 Mar - 5 Mar
8.6/10 Excellent! (1,005 reviews)
Hotels in O Brien with star-rating
Hotels in O Brien with star-rating

3 Star Hotels
19 properties
Recent reviews of O Brien hotels
Recent reviews of O Brien hotels

TownePlace Suites by Marriott Lake City
5/5 Excellent
"Facility/staff"
A verified traveler from Pleasant Lake stayed at TownePlace Suites by Marriott Lake City
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Stay near popular O Brien attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River State Park
- Hotels near Ichetucknee River
- Hotels near Santa Fe River
- Hotels near O'Leno State Park
- Hotels near Lake City Mall
- Hotels near Poe Springs Park
- Hotels near Southside Sports Complex
- Hotels near North Florida Speedway
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Southside Recreation Complex
- Hotels near Stephen Foster State Folk Center
- Hotels near Columbia County Courthouse
- Hotels near Wes Skiles Peacock Springs State Park
- Hotels near Stephen Foster Folk Culture Center
- Hotels near Big Shoals State Park
- Hotels near Lafayette Blue Springs State Park
- Hotels near Florida Department of Transportation
More Accommodation Types in O Brien
O Brien Hotels by Brand
Other Hotels near O Brien, Florida
- Florida Panhandle Hotels
- Lake City Hotels
- Jasper Hotels
- Gulf Coast Hotels
- Alachua Hotels
- Perry Hotels
- Southeastern United States Hotels
- Live Oak Hotels
- High Springs Hotels
- Newberry Hotels
- Madison Hotels
- Old Town Hotels
- Central West Coast Florida Hotels
- Fort White Hotels
- Northern Florida Hotels
- Trenton Hotels
- Branford Hotels
- Mayo Hotels
- Lake Butler Hotels
- White Springs Hotels
Explore more hotels
- Quality Inn Lake City
- Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel
- Best Western Plus Lake City
- Postcard Cabins Gilchrist Springs
- Days Inn by Wyndham Lake City I-75
- Baymont by Wyndham Lake City
- Hampton Inn & Suites Alachua I-75
- Regal Inn
- Quality Inn White Springs Suwanee
- BlueGem Motel
- Tru by Hilton Lake City
- Home2 Suites by Hilton Lake City