Photo by Dr__Vlad

Find hotels in O Brien, FL from AED 220

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Compare 312 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn & Suites Alachua I-75

2.5 star property
9.6 out of 10, Exceptional, (392)
"The rooms were very clean and the staff was friendly. "
The price is AED 434
AED 488 total
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

2.0 star property
4.8 out of 10, (533)
"Property needs full renovation"
The price is AED 253
AED 284 total
includes taxes & fees
6 Apr - 7 Apr
Americas Best Value Inn Alachua

Royal Inn

2.0 star property
7.2 out of 10, Good, (169)
"It's a very old hotel but economically priced and the front desk employee, maybe owner, was very friendly and quick. The bathroom definitely needs updating or a better clean. We chose not to shower due to looking like mold. It may have been a stain as the rest of the room was clean. "
The price is AED 286
AED 322 total
includes taxes & fees
6 Apr - 7 Apr
Royal Inn

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
9.4 out of 10, Exceptional, (1032)
"."
The price is AED 487
AED 548 total
includes taxes & fees
6 Apr - 7 Apr
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Vista Verde Farm Retreat

2.0 star property
10.0 out of 10, Exceptional, (2)
"Park right next to the tiny home. It was clean and spacious. Bring a marshmallow/hotdog stick! "
The price is AED 507
AED 731 total
includes taxes & fees
7 Apr - 8 Apr
Vista Verde Farm Retreat

BlueGem Motel

2.0 star property
9.2 out of 10, Wonderful, (338)
"Pros: Very clean, very comfortable bed and pillows, easy parking, good smell Cons: Front desk is not 24 hours, thin and scratchy towels"
The price is AED 360
AED 405 total
includes taxes & fees
7 Apr - 8 Apr
BlueGem Motel

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (528)
"Nice property in a nice location. The owner is very nice and helpful. "
The price is AED 246
AED 277 total
includes taxes & fees
6 Apr - 7 Apr
Palms Garden Inn

The Blanche

2.0 star property
9.2 out of 10, Wonderful, (123)
"This is an absolutely beautiful historic hotel. "
The price is AED 643
AED 723 total
includes taxes & fees
7 Apr - 8 Apr
The Blanche

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1024)
"Convenient and clean "
The price is AED 297
AED 334 total
includes taxes & fees
6 Apr - 7 Apr
Days Inn by Wyndham Lake City I-10

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (8)
"Nice clean"
The price is AED 413
AED 455 total
includes taxes & fees
17 Apr - 18 Apr
Postcard Cabins Gilchrist Springs

Super 8 by Wyndham Lake City

2.0 star property
7.0 out of 10, Good, (600)
"It was good, very friendly personal. "
The price is AED 298
AED 335 total
includes taxes & fees
6 Apr - 7 Apr
Super 8 by Wyndham Lake City

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (727)
"This was a bare bones hotel. The room was clean and the beds were comfortable. There was Wi-Fi and a tv, and not much else. If all you want is a comfortable bed, then this is the place for you. "
The price is AED 294
AED 331 total
includes taxes & fees
6 Apr - 7 Apr
Driftwood Inn

Regal Inn

2.5 star property
8.6 out of 10, Excellent, (478)
"Read some of the reviews, they were actually pretty good so I thought I would give it a chance. I wrote this review from the hotel room the night that I stayed, not after I’d left and so far no issues. The place was clean, all the lights worked, location was pretty good, and there was a Denny’s just down the road where I could get my breakfast in the morning. Parking lot was well lit and very fast Internet download speeds although pretty bad upload speeds if you wanted to send pictures or video...
The price is AED 268
AED 302 total
includes taxes & fees
6 Apr - 7 Apr
Regal Inn

Courtyard By Marriott Lake City

3.0 star property
9.6 out of 10, Exceptional, (46)
"Fabulous new property!! "
The price is AED 393
AED 442 total
includes taxes & fees
27 Apr - 28 Apr
Courtyard By Marriott Lake City

Days Inn by Wyndham Lake City I-75

2.0 star property
7.2 out of 10, Good, (1026)
"I love the service and friendly "
The price is AED 247
AED 277 total
includes taxes & fees
6 Apr - 7 Apr
Days Inn by Wyndham Lake City I-75

Knights Inn Lake City

1.5 star property
5.4 out of 10, (604)
"Don't let the cheap price scare you away. They have clean comfortable beds and the woman who checked us in was very nice also. This is a great place to stay overnight during your travels."
The price is AED 220
AED 248 total
includes taxes & fees
4 Apr - 5 Apr
Knights Inn Lake City

Holiday Inn & Suites Lake City by IHG

3.0 star property
8.4 out of 10, Very Good, (1007)
"A "
The price is AED 371
AED 417 total
includes taxes & fees
27 Apr - 28 Apr
Holiday Inn & Suites Lake City by IHG

Quality Inn Lake City

2.5 star property
7.8 out of 10, Good, (847)
"Breakfast was weak "
The price is AED 288
AED 324 total
includes taxes & fees
27 Apr - 28 Apr
Quality Inn Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
8.8 out of 10, Excellent, (1070)
"Desk staffed 24 hrs which was nice for a late check in. Pretty clean facility. Breakfast typical and decent. "
The price is AED 377
AED 424 total
includes taxes & fees
6 Apr - 7 Apr
La Quinta Inn & Suite by Wyndham Lake City

Rodeway Inn Lake City I-75

2.0 star property
6.6 out of 10, (370)
"quite "
The price is AED 248
AED 279 total
includes taxes & fees
9 Apr - 10 Apr
Rodeway Inn Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Frequently asked questions

Where is the best place to stay in O Brien?

Courtyard By Marriott Lake City, located 18.2 mi (29.4 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are La Quinta Inn & Suite by Wyndham Lake City and Days Inn by Wyndham Lake City I-75. See all available top hotels, or vacation rentals in O Brien.

What's the top vacation rental in O Brien?

Pet-Friendly Florida Escape w/ Patio & Fire Pit!: Visitors give good reviews to this O Brien vacation home rental, which offers a patio, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other homes for rent in O Brien include Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY. See all vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?

Courtyard By Marriott Lake City: Features free self parking, an outdoor pool, and complimentary wireless internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.

What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.