Photo by Dr__Vlad

Find hotels in O Brien, FL from AED 195

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Compare 323 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn & Suites Alachua I-75

2.5 star property
9.4 out of 10, Exceptional, (406)
"Nice comfy rooms"
The price is AED 428
AED 481 total
includes taxes & fees
25 May - 26 May
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

2.0 star property
4.8 out of 10, (552)
"clean, check in easy"
The price is AED 238
AED 268 total
includes taxes & fees
18 May - 19 May
Americas Best Value Inn Alachua

Royal Inn

2.0 star property
7.2 out of 10, Good, (176)
"Very convenient, clean and the beds were comfortable. Perfect for a quick sleep to rest up before hitting the road again. "
The price is AED 493
AED 554 total
includes taxes & fees
12 Jun - 13 Jun
Royal Inn

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
9.4 out of 10, Exceptional, (1006)
"It's was very clean beds was very comfortable love this hotel "
The price is AED 448
AED 504 total
includes taxes & fees
18 May - 19 May
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Vista Verde Farm Retreat

2.0 star property
10.0 out of 10, Exceptional, (4)
"what a wonderful experience!! our little cabin was absolutely perfect inside and out"
The price is AED 476
AED 697 total
includes taxes & fees
21 May - 22 May
Vista Verde Farm Retreat

BlueGem Motel

2.0 star property
9.2 out of 10, Wonderful, (350)
"nice and simple with a classic motel feel extremely friemdlyamd helpful staff went over nad above to accommodate my later arrival tryuely appreciate it"
The price is AED 306
AED 344 total
includes taxes & fees
15 Jun - 16 Jun
BlueGem Motel

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (543)
"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."
The price is AED 246
AED 277 total
includes taxes & fees
18 May - 19 May
Palms Garden Inn

The Blanche

2.0 star property
9.2 out of 10, Wonderful, (131)
"This is an absolutely beautiful historic hotel. "
The price is AED 630
AED 709 total
includes taxes & fees
19 May - 20 May
The Blanche

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1004)
"Easy location while traveling "
The price is AED 219
AED 246 total
includes taxes & fees
18 May - 19 May
Days Inn by Wyndham Lake City I-10

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (20)
"excellent for a romantic getaway🌷"
The price is AED 360
AED 538 total
includes taxes & fees
29 May - 30 May
Postcard Cabins Gilchrist Springs

Super 8 by Wyndham Lake City

2.0 star property
7.0 out of 10, Good, (613)
"Very clean for a budget motel. "
The price is AED 256
AED 288 total
includes taxes & fees
27 May - 28 May
Super 8 by Wyndham Lake City

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (728)
"Nice, not great or amazing, but nice. Clean room and friendly staff."
The price is AED 195
AED 220 total
includes taxes & fees
20 May - 21 May
Driftwood Inn

Regal Inn

2.5 star property
8.6 out of 10, Excellent, (488)
"Newly renovated older motel. Beds Comfortable and room quiet"
The price is AED 241
AED 271 total
includes taxes & fees
29 May - 30 May
Regal Inn

Courtyard By Marriott Lake City

3.0 star property
9.6 out of 10, Exceptional, (77)
"Awesome hotel, staff was amazing!"
The price is AED 386
AED 434 total
includes taxes & fees
27 May - 28 May
Courtyard By Marriott Lake City

Days Inn by Wyndham Lake City I-75

2.0 star property
7.4 out of 10, Good, (1003)
"Professional staff, clean hotel with modern upgrades. Price was good. Plenty of shopping and dining close by. Check in process was a breeze. "
The price is AED 247
AED 277 total
includes taxes & fees
19 May - 20 May
Days Inn by Wyndham Lake City I-75

Knights Inn Lake City

1.5 star property
5.4 out of 10, (617)
"Love this place!!"
The price is AED 239
AED 269 total
includes taxes & fees
17 May - 18 May
Knights Inn Lake City

Holiday Inn & Suites Lake City by IHG

3.0 star property
8.6 out of 10, Excellent, (1000)
"Very friendly staff, quick check in."
The price is AED 364
AED 409 total
includes taxes & fees
8 Jun - 9 Jun
Holiday Inn & Suites Lake City by IHG

Quality Inn Lake City

2.5 star property
7.8 out of 10, Good, (878)
"The staff was super accomadating ."
The price is AED 262
AED 295 total
includes taxes & fees
15 Jun - 16 Jun
Quality Inn Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
8.8 out of 10, Excellent, (1032)
"Enjoyed the stay"
The price is AED 360
AED 405 total
includes taxes & fees
18 May - 19 May
La Quinta Inn & Suite by Wyndham Lake City

Rodeway Inn Lake City I-75

2.0 star property
6.6 out of 10, (373)
"Courteous staff...quiet place to stay for the night. Needs some renovations...but what hotel doesn't. Would stay again on my travels."
The price is AED 248
AED 279 total
includes taxes & fees
27 May - 28 May
Rodeway Inn Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Frequently asked questions

Where is the best place to stay in O Brien?

La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Courtyard By Marriott Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.

What's the top vacation rental in O Brien?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?

La Quinta Inn & Suite by Wyndham Lake City: Provides on-the-go, an indoor pool, and free self parking. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and Courtyard By Marriott Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.

What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lake City Mall in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.