Photo by Dr__Vlad
Find 2 Star Hotels in O Brien, FL from AED 226
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on O Brien 2 Star Hotels
Compare O Brien 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Americas Best Value Inn Lake City
Americas Best Value Inn Lake City
8.8 out of 10, Excellent, (1003)
The price is AED 262
AED 295 total
includes taxes & fees
24 Feb - 25 Feb

La Quinta Inn & Suite by Wyndham Lake City
La Quinta Inn & Suite by Wyndham Lake City
8.8 out of 10, Excellent, (1011)
The price is AED 372
AED 418 total
includes taxes & fees
27 Feb - 28 Feb

Best Western Plus Lake City
Best Western Plus Lake City
9.2 out of 10, Wonderful, (1005)
The price is AED 456
AED 513 total
includes taxes & fees
2 Mar - 3 Mar

Tru by Hilton Lake City
Tru by Hilton Lake City
9.2 out of 10, Wonderful, (1005)
The price is AED 474
AED 533 total
includes taxes & fees
24 Feb - 25 Feb

Hampton Inn & Suites Lake City
Hampton Inn & Suites Lake City
9.4 out of 10, Exceptional, (934)
The price is AED 480
AED 540 total
includes taxes & fees
2 Mar - 3 Mar

Quality Inn Lake City
Quality Inn Lake City
7.8 out of 10, Good, (829)
The price is AED 309
AED 348 total
includes taxes & fees
9 Mar - 10 Mar

Comfort Suites Lake City
Comfort Suites Lake City
9.6 out of 10, Exceptional, (1002)
The price is AED 452
AED 508 total
includes taxes & fees
3 Mar - 4 Mar

Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75
9.6 out of 10, Exceptional, (378)
The price is AED 559
AED 629 total
includes taxes & fees
2 Mar - 3 Mar
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in O Brien.

Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel
16367 NW 167TH BLVD, Alachua, FL
The price is AED 522 per night from Mar 2 to Mar 3
AED 522
AED 587 total
includes taxes & fees
2 Mar - 3 Mar
9.2/10 Wonderful! (1,001 reviews)
Still don't see what you're looking for?
See all properties in O Brien.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of O Brien hotels
Recent reviews of O Brien hotels

Americas Best Value Inn Lake City
5/5 Excellent
Great Stay for Great Price
"Amazing for the price
Professional, Friendly service
Would stay here anytime in the area"
A verified traveler stayed at Americas Best Value Inn Lake City
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
O Brien Hotels by Star Rating
Stay near popular O Brien attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River State Park
- Hotels near Ichetucknee River
- Hotels near Santa Fe River
- Hotels near Lake City Mall
- Hotels near O'Leno State Park
- Hotels near Southside Sports Complex
- Hotels near Poe Springs Park
- Hotels near North Florida Speedway
- Hotels near Southside Recreation Complex
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Columbia County Courthouse
- Hotels near Stephen Foster State Folk Center
- Hotels near Wes Skiles Peacock Springs State Park
- Hotels near Lafayette Blue Springs State Park
- Hotels near Big Shoals State Park
- Hotels near Stephen Foster Folk Culture Center
- Hotels near Lake City Columbia County Historical Museum
More Accommodation Types in O Brien
Explore more hotels
- Quality Inn Lake City
- Fairfield Inn & Suites Lake City
- Courtyard By Marriott Lake City
- Baymont by Wyndham Lake City
- Quality Inn & Suites Live Oak I-10 Exit 283
- Regal Inn
- Americas Best Value Inn Alachua
- Hampton Inn & Suites Lake City
- Tru by Hilton Lake City
- Home2 Suites by Hilton Lake City
- Days Inn by Wyndham Lake City I-75
- Comfort Suites Lake City
- Quality Inn White Springs Suwanee
- Hampton Inn & Suites Alachua I-75
- Knights Inn Lake City
- Gateway Inn
- Days Inn by Wyndham Lake City I-10
- Holiday Inn Express Hotel & Suites LIVE OAK, an IHG Hotel
- Suwannee River Rendezvous
- BlueGem Motel