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Discover 13,508 Desoto Lakes hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Motel 6 Venice, FL
Motel 6 Venice, FL
8.0 out of 10, Very Good, (155)
The price is AED 345
AED 574 total
includes taxes & fees
6 Apr - 7 Apr

Ramada by Wyndham Venice Hotel Venezia
Ramada by Wyndham Venice Hotel Venezia
7.4 out of 10, Good, (1132)
The price is AED 496
AED 560 total
includes taxes & fees
6 Apr - 7 Apr

Home2 Suites Sarasota I-75 Bee Ridge, FL
Home2 Suites Sarasota I-75 Bee Ridge, FL
9.6 out of 10, Exceptional, (608)
The price is AED 591
AED 668 total
includes taxes & fees
20 Apr - 21 Apr

My Sarasota Getaway
My Sarasota Getaway
5.6 out of 10, (201)
The price is AED 327
AED 370 total
includes taxes & fees
12 Apr - 13 Apr

Holiday Inn Express & Suites Nokomis Sarasota South by IHG
Holiday Inn Express & Suites Nokomis Sarasota South by IHG
9.6 out of 10, Exceptional, (169)
The price is AED 514
AED 581 total
includes taxes & fees
27 Apr - 28 Apr

Home2 Suites by Hilton Nokomis Sarasota Casey Key
Home2 Suites by Hilton Nokomis Sarasota Casey Key
9.2 out of 10, Wonderful, (692)
The price is AED 568
AED 642 total
includes taxes & fees
27 Apr - 28 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Desoto Lakes
Where to stay in Desoto Lakes
Hotels in top Sarasota neighborhoods Learn more about Desoto Lakes

South Sarasota
While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.
Recent reviews of Desoto Lakes hotels
Recent reviews of Desoto Lakes hotels

Comfort Suites Sarasota - Siesta Key
5/5 Excellent
"Stayed one night. Safe and great location. Friendly staff and the room was very clean. The room did have a medicinal smell to it. Maybe the sanitizer they use??? Overall I would recommend and stay here again. "
A verified traveler stayed at Comfort Suites Sarasota - Siesta Key
Posted 11 hours ago
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Hotels in top Sarasota neighborhoods
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Desoto Lakes Hotels by Star Rating
Desoto Lakes Hotels by Brand
Explore more hotels
- The Westin Sarasota
- Carlisle Inn
- Embassy Suites by Hilton Sarasota, FL
- Siesta Key Palms Resort
- Casey Key Resorts - Mainland
- Comfort Suites Sarasota - Siesta Key
- Tropical Breeze Resort
- Bali Hai Beachfront Resort and Spa
- Siesta Key Beach Resort and Suites
- The Ringling Beach House
- Quality Inn Sarasota North Near Lido Key Beach
- The St. Regis Longboat Key Resort