Photo by Jessica King

Find hotels in De Soto, MO from AED 187

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Compare 152 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 star property
9.4 out of 10, Exceptional, (139)
"Many things to do if you don't want to go anywhere. Close to shopping, restaurant. "
The price is AED 584
AED 673 total
includes taxes & fees
31 Mar - 1 Apr
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

The Conner House B&B

3.5 star property
10.0 out of 10, Exceptional, (13)
"Conner House is without parallel in the area - it stands alone by setting a relaxed yet elegant standard. We're treated beyond courtesy and civility with genuine respect and warmth. We've stayed here before and will likely do so again."
The price is AED 528
AED 586 total
includes taxes & fees
1 Apr - 2 Apr
The Conner House B&B

Corner George Inn Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (151)
"Hosts were excellent, very quiet and the breakfast was wonderful"
The price is AED 449
AED 498 total
includes taxes & fees
2 Apr - 3 Apr
Corner George Inn Bed & Breakfast

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (3)
"This place made me look like a rockstar to my wife. I surprised her with a V day getaway. The cabin was awesome. We loved the view of nature from the large window. I made dinner reservations nearby at the weingarten vineyard. The hiking trail along the creek was fun. We ate breakfast right down the road at Kozy. For our final night I cooked steaks over the open fire"
The price is AED 331
AED 356 total
includes taxes & fees
7 Apr - 8 Apr
Postcard Cabins St. Francois

Tiny Houses of French Village

2.5 star property
10.0 out of 10, Exceptional, (2)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
The price is AED 907
AED 1,344 total
includes taxes & fees
25 Mar - 26 Mar
Tiny Houses of French Village

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Clean and comfortable room nicely upgraded bathrooms. Dinner selections offer a great variety and breakfast is good also daily popcorn is nice and the indoor/outdoor pool is a big hit"
The price is AED 479
AED 554 total
includes taxes & fees
20 Apr - 21 Apr
Drury Inn & Suites St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1012)
"Staff courteous and friendly, the happy hour when we arrived was a pleasant surprise after traveling. We enjoyed the restaurant next door and happy to have a restaurant within walking distance. Beds were comfortable, but housekeeping not as reliable as we would have liked. Breakfast was adequate but not great. We liked the location right next to the highway, would stay again if in the area."
The price is AED 331
AED 382 total
includes taxes & fees
31 Mar - 1 Apr
Pear Tree Inn St. Louis Arnold

WoodSpring Suites St. Louis Arnold

2.5 star property
6.0 out of 10, (388)
"Everything "
The price is AED 279
AED 323 total
includes taxes & fees
30 Mar - 31 Mar
WoodSpring Suites St. Louis Arnold

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

2.5 star property
8.0 out of 10, Very Good, (760)
"Stayed for work. Was exactly what I needed for good price. Will stay again if in the area."
The price is AED 356
AED 407 total
includes taxes & fees
20 Apr - 21 Apr
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Quality Inn Festus

3.0 star property
6.8 out of 10, (894)
"Room and bathroom were clean, our room’s carpet had holes and was ripped up by the AC the room smelled moldy. Employees were polite"
The price is AED 282
AED 322 total
includes taxes & fees
19 Apr - 20 Apr
Quality Inn Festus

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (790)
"They had a nice breakfast with many options. Good place to stop. "
The price is AED 328
AED 383 total
includes taxes & fees
6 Apr - 7 Apr
Comfort Inn Festus - St Louis South

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (623)
"Good property! Safe and convenient!"
The price is AED 511
AED 584 total
includes taxes & fees
6 Apr - 7 Apr
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (479)
"Quiet and peaceful. Nice room"
The price is AED 528
AED 601 total
includes taxes & fees
4 Apr - 5 Apr
Hampton Inn Farmington

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (405)
"The staff were absolutely the kindest people. Enjoyed the complementary breakfast each morning. The hotel itself was mostly clean but is starting to look a little aged. We had major rain and several leaking areas. Also were super excited to have an indoor pool available but the water was SO COLD even for my rambunctious 5 year old. 😅"
The price is AED 461
AED 1,115 total
includes taxes & fees
1 Apr - 2 Apr
Holiday Inn Express & Suites Farmington by IHG

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (524)
"Very affordable, easy access, close to shopping and restaurants. The staff was very friendly and accommodating. The property is a little worn, but good value for the money."
The price is AED 221
AED 252 total
includes taxes & fees
25 Mar - 26 Mar
Super 8 by Wyndham Farmington

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (887)
"In the region of competition, it was a budget friendly offering with recently remodeled rooms. The property outside could use some care but room was clean and breakfast satisfactory. Plenty of parking for a truck and trailer. "
The price is AED 191
AED 217 total
includes taxes & fees
6 Apr - 7 Apr
Baymont Inn and Suites by Wyndham Farmington, MO

Quality Inn Farmington

2.5 star property
7.8 out of 10, Good, (786)
"Good for the price. "
The price is AED 187
AED 224 total
includes taxes & fees
7 Apr - 8 Apr
Quality Inn Farmington

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (518)
"Excellent place to stay. Room was clean and nice. Bathroom was clean. Excellent shower. Great breakfast buffet"
The price is AED 426
AED 486 total
includes taxes & fees
1 Apr - 2 Apr
Crown Pointe Lodge, BW Signature Collection

Rosener's Inn and banquet center

2.0 star property
5.0 out of 10, (48)
"It's not that bad as it use to be it is ran very professional now and it's more like a business now not a hang out for people "
The price is AED 194
AED 216 total
includes taxes & fees
1 Apr - 2 Apr
Rosener's Inn and banquet center

Super 8 by Wyndham Bonne Terre

2.0 star property
6.8 out of 10, (452)
"What can be said. It is a Super 8. Essentially the closest hotel to the Bonne Terre Mine, where we were going to be diving. The room was adequate. There was a hole in the blanket, but didn't affect its function. I really can't complain considering the reasonably cheap price. "
The price is AED 187
AED 205 total
includes taxes & fees
6 Apr - 7 Apr
Super 8 by Wyndham Bonne Terre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

Frequently asked questions

Where is the best place to stay in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG is one of the top choices for your stay based on our traveler data. This aparthotel offers free parking and private balconies. Other good options for your visit to the area are Baymont Inn and Suites by Wyndham Farmington, MO and Pear Tree Inn St. Louis Arnold. See all available top hotels, or vacation rentals in De Soto.

What are some of the best vacation rentals that De Soto has to offer?

Cute Ranch -safe and quiet- 1800 sft living space: This vacation home rental near De Soto offers a balcony, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.

What's the best pet-friendly hotel in De Soto?
What are some accommodations with pools in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG: Features 2 outdoor tennis courts, a seasonal outdoor pool, and a sauna. Baymont Inn and Suites by Wyndham Farmington, MO and Pear Tree Inn St. Louis Arnold are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.

What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 7 hotels and other accommodations to choose from. Find out more about De Soto.

What should I do while I'm visiting De Soto?

Natural beauty is on display at Sunrise Lake Beach, Big River, and Victoria Glaces Conservation Area Trailhead. A couple of additional sights to add to your agenda are Washington State Park and Big Lake. Check out what more to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.