Photo by Jessica King

Find hotels in De Soto, MO from AED 187

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Compare 146 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Club Vacations Timber Creek Resort at De Soto

3.5 star property
9.4 out of 10, Exceptional, (139)
"Many things to do if you don't want to go anywhere. Close to shopping, restaurant. "
The price is AED 584
AED 673 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Club Vacations Timber Creek Resort at De Soto

The Conner House B&B

3.5 star property
10.0 out of 10, Exceptional, (13)
"Conner House is without parallel in the area - it stands alone by setting a relaxed yet elegant standard. We're treated beyond courtesy and civility with genuine respect and warmth. We've stayed here before and will likely do so again."
The price is AED 574
AED 637 total
includes taxes & fees
23 Feb - 24 Feb
The Conner House B&B

Corner George Inn Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (151)
"Hosts were excellent, very quiet and the breakfast was wonderful"
The price is AED 472
AED 524 total
includes taxes & fees
25 Feb - 26 Feb
Corner George Inn Bed & Breakfast

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (2)
"This place made me look like a rockstar to my wife. I surprised her with a V day getaway. The cabin was awesome. We loved the view of nature from the large window. I made dinner reservations nearby at the weingarten vineyard. The hiking trail along the creek was fun. We ate breakfast right down the road at Kozy. For our final night I cooked steaks over the open fire"
The price is AED 294
AED 316 total
includes taxes & fees
3 Mar - 4 Mar
Postcard Cabins St. Francois

Tiny Houses of French Village

2.5 star property
10.0 out of 10, Exceptional, (2)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
The price is AED 907
AED 1,344 total
includes taxes & fees
23 Feb - 24 Feb
Tiny Houses of French Village

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1000)
"My boyfriend and I enjoyed the Jacuzzi and the room. Plus, it was very quiet where we were."
The price is AED 446
AED 516 total
includes taxes & fees
2 Mar - 3 Mar
Drury Inn & Suites St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1005)
"It was nice and quiet. "
The price is AED 314
AED 363 total
includes taxes & fees
2 Mar - 3 Mar
Pear Tree Inn St. Louis Arnold

WoodSpring Suites St. Louis Arnold

2.5 star property
6.0 out of 10, (387)
"Everything "
The price is AED 261
AED 301 total
includes taxes & fees
23 Feb - 24 Feb
WoodSpring Suites St. Louis Arnold

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

2.5 star property
8.0 out of 10, Very Good, (748)
"Love everything about our stay we will definitely be back"
The price is AED 337
AED 386 total
includes taxes & fees
25 Feb - 26 Feb
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Quality Inn Festus

3.0 star property
6.8 out of 10, (893)
"Room and bathroom were clean, our room’s carpet had holes and was ripped up by the AC the room smelled moldy. Employees were polite"
The price is AED 301
AED 344 total
includes taxes & fees
28 Feb - 1 Mar
Quality Inn Festus

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (781)
"Comfortable room that was clean except bureau and desk tops which were smeared with some kind of cleaner and not wiped off. Had to use handiwipes to clean up. Nothing special about hotel or breakfast."
The price is AED 316
AED 369 total
includes taxes & fees
24 Feb - 25 Feb
Comfort Inn Festus - St Louis South

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (618)
"It was clean and reasonably priced. The employees were friendly and kind. "
The price is AED 511
AED 584 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (477)
"I liked the property. I objected to the pet fee of $75.00 per night!! That was half of the price of the room! It was late and we were very tired, but I will check into the pet fee policy at Hampton Inn before staying at one again."
The price is AED 496
AED 565 total
includes taxes & fees
28 Feb - 1 Mar
Hampton Inn Farmington

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (405)
"The staff were absolutely the kindest people. Enjoyed the complementary breakfast each morning. The hotel itself was mostly clean but is starting to look a little aged. We had major rain and several leaking areas. Also were super excited to have an indoor pool available but the water was SO COLD even for my rambunctious 5 year old. 😅"
The price is AED 374
AED 1,012 total
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express & Suites Farmington by IHG

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (515)
"Was great"
The price is AED 221
AED 252 total
includes taxes & fees
23 Feb - 24 Feb
Super 8 by Wyndham Farmington

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (857)
"Exceeded my expectations for the price. Good breakfast"
The price is AED 206
AED 234 total
includes taxes & fees
28 Feb - 1 Mar
Baymont Inn and Suites by Wyndham Farmington, MO

Quality Inn Farmington

2.5 star property
7.8 out of 10, Good, (776)
"Was awesome. Actuay far exeded my expectations. In whole dude to the unbelivable beautiful soul they have atcthe front desk. They finaly got it right with the switch of staf. Farmington finaly has some better more welcoming people to greet them now. The Quality Inn. Top Notch."
The price is AED 187
AED 224 total
includes taxes & fees
16 Mar - 17 Mar
Quality Inn Farmington

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (515)
"Nice older rooms. Comfy beds and a gorgeous view facing golf course. Staff was absolutely amazing and super friendly. We had a jet tub in our room and it was just what we needed. "
The price is AED 426
AED 486 total
includes taxes & fees
28 Feb - 1 Mar
Crown Pointe Lodge, BW Signature Collection

Rosener's Inn and banquet center

2.0 star property
5.0 out of 10, (48)
"It's not that bad as it use to be it is ran very professional now and it's more like a business now not a hang out for people "
The price is AED 198
AED 221 total
includes taxes & fees
15 Mar - 16 Mar
Rosener's Inn and banquet center

Super 8 by Wyndham Bonne Terre

2.0 star property
6.8 out of 10, (445)
"What can be said. It is a Super 8. Essentially the closest hotel to the Bonne Terre Mine, where we were going to be diving. The room was adequate. There was a hole in the blanket, but didn't affect its function. I really can't complain considering the reasonably cheap price. "
The price is AED 194
AED 212 total
includes taxes & fees
24 Mar - 25 Mar
Super 8 by Wyndham Bonne Terre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

Frequently asked questions

Where is the best place to stay in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto is one of the top choices for your stay based on our traveler data. This aparthotel offers free parking and private balconies. Other good options for your visit to the area are Pear Tree Inn St. Louis Arnold and Baymont Inn and Suites by Wyndham Farmington, MO. See all available top hotels, or vacation rentals in De Soto.

What are some of the best vacation rentals that De Soto has to offer?

Cute spacious Ranch - very safe area - 4 BR 2B- big fenced yard -1800 sft : This vacation home rental near De Soto has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.

What's the best pet-friendly hotel in De Soto?
What are some accommodations with pools in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto: Features 2 outdoor tennis courts, a seasonal outdoor pool, and a sauna. Pear Tree Inn St. Louis Arnold and Baymont Inn and Suites by Wyndham Farmington, MO are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.

What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 7 hotels and other accommodations to choose from. Find out more about De Soto.

What should I do while I'm visiting De Soto?

Natural beauty is on display at Washington State Park, Big River, and Sunrise Lake Beach. A couple of additional sights to add to your agenda are Valle Lake Beach and Big Lake. Check out what more to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.