Photo by Jessica King

Find hotels in De Soto, MO from AED 187

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Compare 159 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1000)
"Great staff"
The price is AED 446
AED 516 total
includes taxes & fees
20 Apr - 21 Apr
Drury Inn & Suites St. Louis Arnold

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (3)
"This place made me look like a rockstar to my wife. I surprised her with a V day getaway. The cabin was awesome. We loved the view of nature from the large window. I made dinner reservations nearby at the weingarten vineyard. The hiking trail along the creek was fun. We ate breakfast right down the road at Kozy. For our final night I cooked steaks over the open fire"
The price is AED 331
AED 494 total
includes taxes & fees
28 Apr - 29 Apr
Postcard Cabins St. Francois

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1004)
"We enjoyed our stay. Staff very friendly. Wished the bathrooms were alittle bigger."
The price is AED 314
AED 363 total
includes taxes & fees
20 Apr - 21 Apr
Pear Tree Inn St. Louis Arnold

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (629)
"We were in from out of state and everything went perfect!"
The price is AED 481
AED 550 total
includes taxes & fees
20 Apr - 21 Apr
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Tiny Houses of French Village

2.5 star property
10.0 out of 10, Exceptional, (2)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
The price is AED 654
AED 1,074 total
includes taxes & fees
16 Apr - 17 Apr
Tiny Houses of French Village

Corner George Inn Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (151)
"Hosts were excellent, very quiet and the breakfast was wonderful"
The price is AED 439
AED 488 total
includes taxes & fees
17 Apr - 18 Apr
Corner George Inn Bed & Breakfast

The Conner House B&B

3.5 star property
10.0 out of 10, Exceptional, (13)
"Conner House is without parallel in the area - it stands alone by setting a relaxed yet elegant standard. We're treated beyond courtesy and civility with genuine respect and warmth. We've stayed here before and will likely do so again."
The price is AED 511
AED 567 total
includes taxes & fees
16 Apr - 17 Apr
The Conner House B&B

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (481)
"The beds are like laying on a cloud. The pool area was super clean although the jacuzzi was closed which was a total bummer. But. The area, property were clean and most of all, it felt safe!! "
The price is AED 434
AED 494 total
includes taxes & fees
27 Apr - 28 Apr
Hampton Inn Farmington

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (405)
"The staff were absolutely the kindest people. Enjoyed the complementary breakfast each morning. The hotel itself was mostly clean but is starting to look a little aged. We had major rain and several leaking areas. Also were super excited to have an indoor pool available but the water was SO COLD even for my rambunctious 5 year old. 😅"
The price is AED 419
AED 1,046 total
includes taxes & fees
27 Apr - 28 Apr
Holiday Inn Express & Suites Farmington by IHG

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (522)
"Nice staff"
The price is AED 460
AED 523 total
includes taxes & fees
11 May - 12 May
Crown Pointe Lodge, BW Signature Collection

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (917)
"Great place for the price, excellent breakfast."
The price is AED 194
AED 221 total
includes taxes & fees
27 Apr - 28 Apr
Baymont Inn and Suites by Wyndham Farmington, MO

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
8.0 out of 10, Very Good, (774)
"Room was decent. Could tell the hotel is older. Caulking in bathroom was horrible, lights in restroom flickering. Room and sheets were clean, bedframe creaked badly. Hallways smelled musty. For just a place to sleep and explore the area it did the job"
The price is AED 387
AED 443 total
includes taxes & fees
28 Apr - 29 Apr
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (528)
"Clean rooms, comfortable beds, and friendly staff!!"
The price is AED 221
AED 252 total
includes taxes & fees
17 Apr - 18 Apr
Super 8 by Wyndham Farmington

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (802)
"Nice full breakfast. Bed was comfortable."
The price is AED 328
AED 383 total
includes taxes & fees
20 Apr - 21 Apr
Comfort Inn Festus - St Louis South

Quality Inn Farmington

2.5 star property
7.8 out of 10, Good, (796)
"The hotel was under renovation but it didnt interrupt any part of our stay except for the Hot Tub wasn't back up and running, but wasnt a problem."
The price is AED 187
AED 224 total
includes taxes & fees
28 Apr - 29 Apr
Quality Inn Farmington

Super 8 by Wyndham Potosi

2.0 star property
7.0 out of 10, Good, (346)
"There's no bed bugs as some of the "big rich" people said. We checked in here with my kids, they're in the middle of renovations but the room we were in was spacious and comfortable. NO BED BUGS!!! "
The price is AED 194
AED 211 total
includes taxes & fees
1 May - 2 May
Super 8 by Wyndham Potosi

Super 8 by Wyndham Bonne Terre

2.0 star property
6.8 out of 10, (456)
"Staff was very friendly "
The price is AED 187
AED 205 total
includes taxes & fees
21 Apr - 22 Apr
Super 8 by Wyndham Bonne Terre

YMCA Trout Lodge

2.0 star property
The price is AED 724
AED 776 total
includes taxes & fees
16 Apr - 17 Apr
YMCA Trout Lodge

WoodSpring Suites St. Louis Arnold

2.5 star property
6.0 out of 10, (391)
"Jeff, Amber and Melissa was amazing. Will stay again. #TEXASGIRL"
The price is AED 279
AED 323 total
includes taxes & fees
1 May - 2 May
WoodSpring Suites St. Louis Arnold

Rosener's Inn and banquet center

2.0 star property
5.0 out of 10, (48)
"It's not that bad as it use to be it is ran very professional now and it's more like a business now not a hang out for people "
The price is AED 198
AED 221 total
includes taxes & fees
29 Apr - 30 Apr
Rosener's Inn and banquet center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

Frequently asked questions

Where is the best place to stay in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG is one of the top choices for your stay based on our traveler data. This aparthotel offers free parking and private balconies. Other good options for your visit to the area are Pear Tree Inn St. Louis Arnold and Baymont Inn and Suites by Wyndham Farmington, MO. See all available top hotels, or vacation rentals in De Soto.

What are some of the best vacation rentals that De Soto has to offer?

Cute Ranch -safe and quiet- 1800 sft living space: This vacation home rental near De Soto offers a balcony, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.

What's the best pet-friendly hotel in De Soto?
What are some accommodations with pools in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG: Features 2 outdoor tennis courts, a seasonal outdoor pool, and a sauna. Lakeside Private Villa | 5-Hole Golf On-Site and Pear Tree Inn St. Louis Arnold are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.

What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 7 hotels and other accommodations to choose from. Find out more about De Soto.

What should I do while I'm visiting De Soto?

Natural beauty is on display at Sunrise Lake Beach, Big River, and Victoria Glaces Conservation Area Trailhead. A couple of additional sights to add to your agenda are Washington State Park and Big Lake. Check out what more to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.