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Find hotels in De Soto, MO from AED 187
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Compare 159 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
9.6 out of 10, Exceptional, (1000)
The price is AED 446
AED 516 total
includes taxes & fees
20 Apr - 21 Apr

Postcard Cabins St. Francois
Postcard Cabins St. Francois
10.0 out of 10, Exceptional, (3)
The price is AED 331
AED 494 total
includes taxes & fees
28 Apr - 29 Apr

Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
9.2 out of 10, Wonderful, (1004)
The price is AED 314
AED 363 total
includes taxes & fees
20 Apr - 21 Apr

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
9.4 out of 10, Exceptional, (629)
The price is AED 481
AED 550 total
includes taxes & fees
20 Apr - 21 Apr

Tiny Houses of French Village
Tiny Houses of French Village
10.0 out of 10, Exceptional, (2)
The price is AED 654
AED 1,074 total
includes taxes & fees
16 Apr - 17 Apr

Corner George Inn Bed & Breakfast
Corner George Inn Bed & Breakfast
9.0 out of 10, Wonderful, (151)
The price is AED 439
AED 488 total
includes taxes & fees
17 Apr - 18 Apr
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More cheap stays in De Soto
More cheap stays in De Soto

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
The price is AED 200 per night from Apr 22 to Apr 23
AED 200
AED 227 total
includes taxes & fees
22 Apr - 23 Apr
8/10 Very Good! (916 reviews)
Hotels in De Soto with star-rating
Hotels in De Soto with star-rating

4 Star Hotels
1 properties
Stay near popular De Soto attractions
Stay near popular De Soto attractions
Recent reviews of De Soto hotels
Recent reviews of De Soto hotels

Crown Pointe Lodge, BW Signature Collection
5/5 Excellent
"Nice staff"
A verified traveler stayed at Crown Pointe Lodge, BW Signature Collection
Posted 2 days ago
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Stay near popular De Soto attractions
- Hotels near Mississippi River
- Hotels near Bonne Terre Mine
- Hotels near Meramec State Park
- Hotels near Meramec River
- Hotels near Pickle Springs Natural Area
- Hotels near Hawn State Park
- Hotels near St. Joe State Park
- Hotels near St. Francois State Park
- Hotels near Big River
- Hotels near Washington State Park
- Hotels near Crown Pointe Golf Club
- Hotels near Fort de Chartes
Hotels near De Soto Airports
De Soto Hotels by Brand
Other Hotels near De Soto, Missouri
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- Potosi Hotels
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- Imperial Hotels
- Tesson Ferry Hotels
- Waterloo Hotels
- Bourbon Hotels
- Park Hills Hotels
- Pevely Hotels
Explore more hotels
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Super 8 by Wyndham Farmington
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- Crown Pointe Lodge, BW Signature Collection
- Cute Ranch -safe and quiet- 1800 sft living space
- Super 8 by Wyndham Potosi
- Quality Inn Festus
- Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
- Lake Haven - Updated Mid Century Cabin Only 35 Mins from St. Louis