Photo by Jessica King
Find 2 Star Hotels in De Soto, MO from AED 187
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on De Soto 2 Star Hotels
Compare De Soto 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
8.0 out of 10, Very Good, (919)
The price is AED 200
AED 227 total
includes taxes & fees
28 Apr - 29 Apr

Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
9.2 out of 10, Wonderful, (1002)
The price is AED 314
AED 363 total
includes taxes & fees
20 Apr - 21 Apr

Comfort Inn Festus - St Louis South
Comfort Inn Festus - St Louis South
8.0 out of 10, Very Good, (802)
The price is AED 328
AED 383 total
includes taxes & fees
20 Apr - 21 Apr

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
8.0 out of 10, Very Good, (775)
The price is AED 387
AED 443 total
includes taxes & fees
28 Apr - 29 Apr

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
9.4 out of 10, Exceptional, (629)
The price is AED 518
AED 592 total
includes taxes & fees
27 Apr - 28 Apr

Quality Inn Farmington
Quality Inn Farmington
7.8 out of 10, Good, (796)
The price is AED 187
AED 224 total
includes taxes & fees
1 May - 2 May

Super 8 by Wyndham Farmington
Super 8 by Wyndham Farmington
8.0 out of 10, Very Good, (528)
The price is AED 221
AED 252 total
includes taxes & fees
18 Apr - 19 Apr

Super 8 by Wyndham Bonne Terre
Super 8 by Wyndham Bonne Terre
6.8 out of 10, (456)
The price is AED 187
AED 205 total
includes taxes & fees
28 Apr - 29 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in De Soto.

Drury Inn & Suites St. Louis Arnold
3800 State Rt 141, Arnold, MO
The price is AED 479 per night from May 4 to May 5
AED 479
AED 554 total
includes taxes & fees
4 May - 5 May
9.4/10 Exceptional! (1,001 reviews)
Still don't see what you're looking for?
See all properties in De Soto.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about De Soto
Get away to De Soto! Enjoy the local cuisine and more.

Photo by Jessica King
Open Photo by Jessica King
Recent reviews of De Soto hotels
Recent reviews of De Soto hotels

Super 8 by Wyndham Bonne Terre
5/5 Excellent
"Staff was very friendly "
A verified traveler stayed at Super 8 by Wyndham Bonne Terre
Posted 8 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
De Soto Hotels by Star Rating
Stay near popular De Soto attractions
- Hotels near Mississippi River
- Hotels near Bonne Terre Mine
- Hotels near Meramec State Park
- Hotels near Meramec River
- Hotels near Pickle Springs Natural Area
- Hotels near Hawn State Park
- Hotels near St. Joe State Park
- Hotels near St. Francois State Park
- Hotels near Big River
- Hotels near Washington State Park
- Hotels near Crown Pointe Golf Club
- Hotels near Fort de Chartes
Explore more hotels
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Super 8 by Wyndham Farmington
- Super 8 by Wyndham Bonne Terre
- Quality Inn Farmington
- Postcard Cabins St. Francois
- Hampton Inn Farmington
- Crown Pointe Lodge, BW Signature Collection
- Cute Ranch -safe and quiet- 1800 sft living space
- Super 8 by Wyndham Potosi
- Quality Inn Festus
- Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
- Lake Haven - Updated Mid Century Cabin Only 35 Mins from St. Louis
- Cabin 1 at the Pallet Factory
- Cozy country setting 4 miles from route 66
- Treehouse and Hot Tub on 10acres - Pet Friendly!
- Holiday Inn Express & Suites Farmington by IHG
- Serenity Log Inn -Log out and Log Inn to Serenity
- Couples Retreat with hot tub (cabin2)
- The Conner House B&B
- Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE