Search Vacation Homes in South Carolina Midlands

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Compare 762 Vacation Homes in South Carolina Midlands with updated reviews, rates, and availability.

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.6 out of 10, Exceptional, (17)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion

Cozy 4 bedroom with spiral staircase and fireplace

10.0 out of 10, Exceptional, (4)
"Accommodating and as described. Fast communication. "
The price is AED 680
AED 872 total
includes taxes & fees
16 Feb - 17 Feb
Cozy 4 bedroom with spiral staircase and fireplace

Great Back Deck and Yard - The Bright Brick Beauty

8.2 out of 10, Very Good, (22)
"The house is beautiful, the neighborhood is quiet and the host responds to any and all questions quickly. The house also is minutes away from many stores which was very convenient! I’d definitely book again if I’m ever in SC."
Great Back Deck and Yard - The Bright Brick Beauty

Mind Blowing Sunsets on a Gated Peninsula Property with a White Sand Beach

10.0 out of 10, Exceptional, (42)
"My family and I had a wonderful 5 days at this property. There were plenty of comfortable bedrooms to accommodate our whole group with room to spare. Very pleased with the amount of bath towels and beach towels provided along with the many toys for the lake. Our host was very accommodating and we all appreciated that. If we are ever back in the area again, we will certainly book again!"
Mind Blowing Sunsets on a Gated Peninsula Property with a White Sand Beach

Hidden Oasis of West Columbia

9.2 out of 10, Wonderful, (7)
"I enjoyed the stay love the property love everything only issue was could not figure out how to get the heat to work and it was freezing in there. Other than that it’s nice inconvenient. I will use again when I visit the area."
Hidden Oasis of West Columbia

Lake Cottage in Chapin with Private Dock

10.0 out of 10, Exceptional, (1)
"We had a wonderful stay over Christmas and will definitely book again! Everything was as pictured and advertised and the hosts were really great to work with!!! Definitely recommend. "
Lake Cottage in Chapin with Private Dock

Large late1800's home within walking distance to Opera House and downtown.

10.0 out of 10, Exceptional, (21)
"Enjoyed our stay visiting family nearby! Great location, beautiful cozy home, and it met all our needs!"
The price is AED 551
AED 1,337 total
includes taxes & fees
18 Feb - 19 Feb
Large late1800's home within walking distance to Opera House and downtown.

Blue House on the Hill | Mins to USC | Sleeps 6

8.8 out of 10, Excellent, (13)
"A group of six, 39 and up came came for a wedding and preceding activities. The location was PERFECT. 7-9 minutes from Main Street. The house was clean, the decorum was modern and chic. The beds were PHENOMENAL! So comfortable and all my group was in agreement. We have another trip to Columbia and would love to rent again."
Blue House on the Hill | Mins to USC | Sleeps 6

Your perfect getaway nestled in the heart of Aiken.

10.0 out of 10, Exceptional, (6)
"This house comfortably accommodated our family of nine with plenty of room for each couple to have their own get away location within the house and plenty of common areas to share family time together. In addition the location was great. We walked two short blocks to enjoy downtown Aiken, had short drives to enjoy good food, and it took less than 30 minutes to get to the Augusta airport. Finally the house was beautiful, well maintained, and had great outdoor spaces."
The price is AED 3,820
AED 5,805 total
includes taxes & fees
16 Feb - 17 Feb
Your perfect getaway nestled in the heart of Aiken.

Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam!

9.8 out of 10, Exceptional, (121)
"Beautiful home with plenty to do."
The price is AED 826
AED 1,428 total
includes taxes & fees
17 Feb - 18 Feb
Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam!

The Turquoise Door in Town of Lexington

9.8 out of 10, Exceptional, (92)
"It was indeed great! Will be back"
The price is AED 364
AED 1,138 total
includes taxes & fees
16 Feb - 17 Feb
The Turquoise Door in Town of Lexington

Family House on Lake Murray. 6 bedroom 6 1/2 bath house with big water view.

10.0 out of 10, Exceptional, (91)
"The home was well equipped with everything we needed and more to spend quality time gathering with family - both inside and outside the home in the spacious backyard and patio areas. Thank you to the Nykamp family for not just opening their home, but ensuring all amenities were well stocked so we didn’t have to worry about anything beyond our basic needs and enjoying each other. I also appreciate their responsiveness when contacted about anything regarding the home. "
Family House on Lake Murray. 6 bedroom 6 1/2 bath house with big water view.

NoMa Green House

10.0 out of 10, Exceptional, (44)
"This house was amazing! Host was very helpful "
NoMa Green House

Beautiful 4 bedroom Lakehouse on a deep water cove on Lake Greenwood.

10.0 out of 10, Exceptional, (172)
"Great property for multiple families or grown children with their own. Lots of activities and games at the house even though it was winter, and a large common area and large dining table. Enjoyed some of the outdoors and would be an amazing place in the summer."
Beautiful 4 bedroom Lakehouse on a deep water cove on Lake Greenwood.

Lake Murray Oasis - 4BR/4BA w/ Pool-HotTub-GameRoom-Beach Area-Playset-Firepit!

Lake Murray Oasis - 4BR/4BA w/ Pool-HotTub-GameRoom-Beach Area-Playset-Firepit!

Tree House feel overlooking Glencairn Gardens

10.0 out of 10, Exceptional, (2)
"This property was exactly as advertised. The place was clean, well stocked with essentials and comfy. Will stay again if we're in the area again!"
The price is AED 459
AED 963 total
includes taxes & fees
16 Feb - 17 Feb
Tree House feel overlooking Glencairn Gardens

Lone Magnolia Historic Home. Peaceful and elegant.

10.0 out of 10, Exceptional, (18)
"We enjoyed our stay at the lovely Lone Magnolia! The house has lovely southern charm and was beautiful appointed. Beds were very comfortable! The owner was very responsive. Close to everything. I would stay here again. "
Lone Magnolia Historic Home. Peaceful and elegant.

Walking distance from one of South Carolina's top Medical centers.

9.8 out of 10, Exceptional, (35)
"Great location and well maintained home. "
The price is AED 547
AED 909 total
includes taxes & fees
2 Mar - 3 Mar
Walking distance from one of South Carolina's top Medical centers.

Downtown Aiken- The Collins Property

10.0 out of 10, Exceptional, (35)
"Bethany’s place was the best! We will be back. "
The price is AED 643
AED 1,288 total
includes taxes & fees
16 Feb - 17 Feb
Downtown Aiken- The Collins Property

Mins to Lake Murray & Downtown! Serene on Sonning

8.8 out of 10, Excellent, (6)
"Visited my son and family who live in Columbia. Had a great visit. House was spacious and well located."
Mins to Lake Murray & Downtown! Serene on Sonning
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in South Carolina Midlands

stayAPT Suites Columbia-Irmo Harbison

2.5 star property
8.6 out of 10, Excellent, (281)
"Love this place! Really clean and very nice check in/check out people! Definitely would stay again!"
stayAPT Suites Columbia-Irmo Harbison

stayAPT Suites Rock Hill

2.5 star property
8.6 out of 10, Excellent, (166)
"Very good "
stayAPT Suites Rock Hill

The Hangar Lofts Hotel

2.5 star property
8.6 out of 10, Excellent, (59)
"The place we stayed at was 001. It was very clean and met all of our needs. We were there for a USC graduation."
The price is AED 543
AED 608 total
includes taxes & fees
16 Feb - 17 Feb
The Hangar Lofts Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.