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Check prices for these dates

Next weekend
18 Apr - 20 Apr
In two weeks
25 Apr - 27 Apr
In one month
9 May - 11 May
In two months
6 Jun - 8 Jun

Compare 76 Vacation Homes in Santee with updated reviews, rates, and availability.

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Marina

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

9.8 out of 10, Exceptional, (227)
"great place for a fishing trip in february"
The price is AED 826
AED 1,646 total
includes taxes & fees
22 Apr - 23 Apr
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Miscellaneous

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

10.0 out of 10, Exceptional, (141)
"We enjoyed a great weekend of fishing and the NASCAR race. Our stay was fabulous, and we look forward to coming back! "
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Exterior

New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

9.8 out of 10, Exceptional, (165)
"This house is so spacious! There’s plenty of bedrooms and bathrooms. The view is great, the neighborhood is quiet, and the host is very easy to get in touch with! Really enjoyed my stay, I will be back. "
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Lake Home walking distance to Marina and 2 more boat landings within a Mile!
Fridge, microwave, oven, stovetop

Lake Home walking distance to Marina and 2 more boat landings within a Mile!

9.8 out of 10, Exceptional, (75)
"Great location for fishing with a pull through driveway "
Lake Home walking distance to Marina and 2 more boat landings within a Mile!
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Fridge, microwave, oven, stovetop

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

9.2 out of 10, Wonderful, (30)
"Loved the quiet surroundings host was very friendly and helpful. This is our new vacation spot at lake Marion "
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Beautiful lake home to make your family vacation extra special!
Fridge, microwave, oven, stovetop

Beautiful lake home to make your family vacation extra special!

9.0 out of 10, Wonderful, (51)
"House was nice, clean, and has everything you need."
Beautiful lake home to make your family vacation extra special!
Archie's Lake Daze Cottage
Property grounds

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (69)
"The men of the family had a blast at this cottage! They spent the days kayaking and laying in the hammock and spent the nights making smores and playing pool! They even caught a few fish, in March! "
Archie's Lake Daze Cottage
Lake Marion Lakehouse with 180° lake view
Beach

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (52)
"We enjoyed our stay so much! We fished a lot and caught 7 bream and 1 catfish. We cooked and ate all of them! So fresh and delicious. We spent most of the time outside but the house was clean and comfortable. Thank you for sharing your property with us!"
Lake Marion Lakehouse with 180° lake view
Relax by Lake Marion - A lake home with you in mind.
Property grounds

Relax by Lake Marion - A lake home with you in mind.

9.4 out of 10, Exceptional, (68)
"Scott’s place was absolutely perfect for our family of 8 adults and 2 children (8 and 5). The lakefront property and view was breathtaking, serene. We loved the openness of the house and especially how clean it was. Fishing from the dock was an added bonus. Caught a HUGE catfish, but released it. The kids didn’t want to take it “out of its home.” :) We definitely recommend staying here. "
Relax by Lake Marion - A lake home with you in mind.
Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!
Terrace/patio

Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!

8.6 out of 10, Excellent, (10)
"My nieces, cousins & their kids traveled from Texas to SC to surprise my daughter, son in law & precious granddaughters. We needed room & activities so that we could hang at the house, enjoy the visit & still keep the kids happy & this foot the bill! John was quick to help w/any special needs/issues, would definitely stay here again but hope I dont have to becuase I want my babies home!"
Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!
Life is better at the Lake Lakefront home that sleeps 13!
Beach

Life is better at the Lake Lakefront home that sleeps 13!

10.0 out of 10, Exceptional, (4)
"Our stay was excellent! Morgan was super helpful and very friendly. Views were gorgeous! 10 out of 10 recommend! "
Life is better at the Lake Lakefront home that sleeps 13!
Mel's Cottage on the Water: Modern + Comfy Home!
Private kitchen

Mel's Cottage on the Water: Modern + Comfy Home!

Mel's Cottage on the Water: Modern + Comfy Home!
LAKE MARION LAKE FRONT VACATION RENTAL
Terrace/patio

LAKE MARION LAKE FRONT VACATION RENTAL

9.6 out of 10, Exceptional, (80)
"Very good "
LAKE MARION LAKE FRONT VACATION RENTAL
Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!
Fridge, microwave, oven, stovetop

Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!

2.0 star property
9.0 out of 10, Wonderful, (2)
"The lake home has tons of natural light and we loved watching the many beautiful geese. The house is situated in a safe and lovely neighborhood. It’s a great area to take a quiet morning or afternoon walk. The open living room area is a great place for families. Our teens loved the board games and puzzle provided for guests. Maggie was a great host. She was responsive and very good to deal with. The back deck was great for grilling….. with a choice of a propane or charcoal grill. We enjoyed a...
Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Exterior

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

10.0 out of 10, Exceptional, (35)
"Perfect for a fun fishing trip! House was extremely close to nice boat ramp , with a dock to keep your boat tied up, and not have the hassle of going to the boat landing every day . House was very clean and relaxing . Amazing place for an amazing trip ! 10/10"
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Tom Charles Goat Island Fishing Retreat
Miscellaneous

Tom Charles Goat Island Fishing Retreat

9.8 out of 10, Exceptional, (49)
"Nice and quiet and convenient. "
Tom Charles Goat Island Fishing Retreat
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Property grounds

The Bunkhouse at St Julien - Vintage Waterfront Lake House

9.8 out of 10, Exceptional, (19)
"plenty of room, quiet, and perfect for a family getaway"
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Lake Marion Getaway!
TV

Lake Marion Getaway!

2.0 star property
9.2 out of 10, Wonderful, (35)
"Very nice host. Place was clean and had plenty of room. Family enjoyed their stay. "
Lake Marion Getaway!
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Microwave, oven, stovetop, dishwasher

Taw Caw Creek Rental - perfect for fishermen - NO PETS

10.0 out of 10, Exceptional, (19)
"Joseph responded quickly to any questions and place was very clean, easy access with boats wide driveway , had most things needed in kitchen . "
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Fabulous Location on southern shores of Lake Marion
Property grounds

Fabulous Location on southern shores of Lake Marion

9.4 out of 10, Exceptional, (12)
"Had a great time - beautiful weather with a group of friends to celebrate my brothers birthday."
Fabulous Location on southern shores of Lake Marion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Santee

Executive 2 BR/2 BA Lakefront Corner Suite Condo
Outdoor pool

Executive 2 BR/2 BA Lakefront Corner Suite Condo

9.0 out of 10, Wonderful, (32)
"Loved everything about this VRBO. We felt like we’re were at home with the most beautiful view. Have already booked for next year. The Host was responsive and the ease of this rental was beyond compare. Highly recommend. "
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Sunsets on Lake Marion
Miscellaneous

Sunsets on Lake Marion

9.8 out of 10, Exceptional, (7)
"Great place to stay. "
Sunsets on Lake Marion
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Aerial view

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (30)
"We needed a place with two separate bedrooms. This property fit the bill. Perfect for our trip. Nice accommodations. Would definitely recommend this property. "
The price is AED 545
AED 1,420 total
includes taxes & fees
21 Apr - 22 Apr
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.