Photo by Cindy Keese

Find 4 Star Hotels in Seneca, SC from AED 533

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Check availability on Seneca 4 Star Hotels

Compare Seneca 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (544)
"The staff was lovely and very helpful and cheery. The property was great, well decorated, close to campus clean and the AC worked extremely well (so many hotels these days put a regulator on AC where you can’t get it below a certain number despite setting it to a certain number). Love that they employ people with disabilities. Well done Shepherd hotel!"
The price is AED 621
AED 689 total
includes taxes & fees
11 May - 12 May
The Shepherd Hotel Downtown Clemson
The Abernathy of Clemson
Flat-screen TV

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (504)
"The perfect option with super close proximity to Clemson University"
The price is AED 768
AED 852 total
includes taxes & fees
20 Apr - 21 Apr
The Abernathy of Clemson
Liberty Hall Bed and Breakfast
Front of property

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (62)
"If perfection could be a rating - that is what I’d rate Liberty Hall. My wife and I loved the location and we didn’t feel like we were tagged and quartered into a stall like cattle at most other places to stay. The breakfast each morning was exquisite. Angela really took care of us and we will certainly stay again."
Liberty Hall Bed and Breakfast
Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is AED 365
AED 1,568 total
includes taxes & fees
27 Apr - 28 Apr
Lake Hartwell Frank Howard Home Clemson
Belvedere
Family House, 4 Bedrooms, Patio, Courtyard View | Bathroom | Combined shower/tub, free toiletries, hair dryer, bidet

Belvedere

4.0 star property
8.0 out of 10, Very Good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere
Pendleton
Exterior

Pendleton

4.0 star property
Pendleton
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
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Learn more about Seneca

Escape to Seneca! Enjoy its sports, lake views, and coffee.

See all hotels in Seneca
View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Seneca?
To book a 4-star hotel in Seneca that fits your budget, use Expedia’s handy search filters. Check out the available options during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most wallet-friendly stay first.

  • Search for the lowest price from AED 533

What's the difference between 5-star and 4-star hotels in Seneca?
If you decide to vacation at a 4-star hotel in Seneca, you’ll usually find lots of amenities to make sure you’re relaxed, such as a gym, pool and restaurant. You can look forward to excellent service and deluxe accommodations. Choose a 5-star hotel and you’ll get a few extra perks — think around-the-clock concierge, on-site spas and opulent turndown services. You’ll most likely get additional amenities and first-class services at a 5-star stay, but both are fabulous options for luxury guests.
Does Seneca have any 4-star all-inclusive resorts?
Finding your dream resort in Seneca is as simple as entering your dates and destination, and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or go for a standard 4-star resort in or around this much-loved destination.