Photo by Cindy Keese

Find 4 Star Hotels in Seneca, SC from AED 426

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Compare Seneca 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson
Room

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (448)
"Very warm beautiful upscale property. Very comfortable and luxurious rooms. Great location. Very friendly and attentive staff. "
The price is AED 584
AED 648 total
includes taxes & fees
1 Jan - 2 January 2025
The Shepherd Hotel Downtown Clemson
The Abernathy of Clemson
Room

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (479)
"Very clean and comfortable. We had a great stay"
The price is AED 547
AED 608 total
includes taxes & fees
28 Dec - 29 Dec
The Abernathy of Clemson
Liberty Hall Bed and Breakfast
Front of property

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (47)
"A great place to stay close to Clemson University..we were actually going to a party close by, so this worked perfectly for us..beautiful home and property; quiet and relaxing. The hosts are very friendly..breakfast was so delicious!! "
The price is AED 596
AED 661 total
includes taxes & fees
7 Jan - 8 January 2025
Liberty Hall Bed and Breakfast
Lake Hartwell Frank Howard Home Clemson
Front of property

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is AED 426
AED 1,635 total
includes taxes & fees
1 Jan - 2 January 2025
Lake Hartwell Frank Howard Home Clemson
Belvedere
Front of property

Belvedere

4.0 star property
Belvedere
228 Lakeland
Exterior

228 Lakeland

4.0 star property
228 Lakeland
Pendleton
Front of property

Pendleton

4.0 star property
Pendleton
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Seneca?
To book a 4-star hotel in Seneca that fits your budget, use Expedia’s handy search filters. Check out the available options during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most wallet-friendly stay first.

  • Search for the lowest price from AED 426

What's the difference between 5-star and 4-star hotels in Seneca?
If you decide to vacation at a 4-star hotel in Seneca, you’ll usually find lots of amenities to make sure you’re relaxed, such as a gym, pool and restaurant. You can look forward to excellent service and deluxe accommodations. Choose a 5-star hotel and you’ll get a few extra perks — think around-the-clock concierge, on-site spas and opulent turndown services. You’ll most likely get additional amenities and first-class services at a 5-star stay, but both are fabulous options for luxury guests.
Does Seneca have any 4-star all-inclusive resorts?
Finding your dream resort in Seneca is as simple as entering your dates and destination, and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or go for a standard 4-star resort in or around this much-loved destination.