Photo by Hideki Yamagata

Find Resorts & Hotels with Spas in San Francisco

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Check availability on San Francisco Resorts & Hotels with Spas

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Compare San Francisco Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (853)
"Great place to stay"
The price is AED 468
AED 515 total
includes taxes & fees
11 Apr - 12 Apr
Sheraton Grand Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1154)
"Love the staff"
The price is AED 1,135
AED 1,248 total
includes taxes & fees
25 Apr - 26 Apr
JW Marriott Panama

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (791)
"I didn't like that I had to ask for the room to be looked at 3 of 4 days "
The price is AED 418
AED 460 total
includes taxes & fees
6 Apr - 7 Apr
Aloft Panama

Plaza Paitilla Inn Hotel

3.5 star property
9.2 out of 10, Wonderful, (2097)
"This is my 2nd time staying at Paitilla Inn hotel. The rooms have been updated since 2019 and the bay view is always a must. It's close to everything including the walk along the malecon to enjoy some street food and culture plus it gives you full access to all of restaurants to view in the area just walking the malecon. Don't forget to feed the cats that walk along the malecon walls. I like the breakfast buffet but next time please include BACON. Beware of the birds that land on your plate...
The price is AED 346
AED 381 total
includes taxes & fees
3 Apr - 4 Apr
Plaza Paitilla Inn Hotel

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (441)
"The Residence inn in Panama is at a great location. Easy access to great restaurants, close to a 5 star mall, and great location for rental launch into the rest of Panama. The rooms are clean and roomy. Great kitchen with all you might need . The breakfast was excellent with a selection including omelet bar . I strongly recommend staying at this great resort. "
The price is AED 528
AED 580 total
includes taxes & fees
18 Apr - 19 Apr
Residence Inn by Marriott Panama City

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (828)
"10/10"
The price is AED 467
AED 513 total
includes taxes & fees
4 Apr - 5 Apr
Megapolis Hotel Panamá

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1053)
"Very clean, and a great location. Footsteps away from great shopping, food and essentials. Will definitely stay there again"
The price is AED 465
AED 512 total
includes taxes & fees
18 Apr - 19 Apr
Courtyard by Marriott Panama Multiplaza Mall

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.4 out of 10, Exceptional, (1206)
"The staff are amazingly curteous "
The price is AED 367
AED 404 total
includes taxes & fees
1 Apr - 2 Apr
Ramada Plaza By Wyndham Panama Punta Pacífica

Decapolis Hotel Panama City

4.0 star property
8.4 out of 10, Very Good, (1351)
"Fantastic stay. Clean and front desk person was great with providing details about places to visit. "
The price is AED 310
AED 341 total
includes taxes & fees
31 Mar - 1 Apr
Decapolis Hotel Panama City

Diaphanous Urban Apartment

3.5 star property
9.2 out of 10, Wonderful, (5)
"The apartment is nice but could definitely use some love! Details like the missing shower caddy, missing bathroom sink plug, broken kitchen stools, half-broken AC remote and others took an impact on the comfort, but it was overall still nice. The WiFi was very fast and convenient. If you plan on ordering food, make sure to add that it must be brought up to the apartment door. The check-in took a long time as the security guard (no "front desk", just a security guard booth) was very confused,...
Diaphanous Urban Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in San Francisco?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Be sure to enjoy the many popular restaurants during your stay. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in San Francisco?
Decapolis Hotel Panama City is a top spa hotel featuring a casino, a fitness center, a hair salon, and a bar. Treat yourself to a facial, body scrub, or detox wrap at Decapolis SPA. Other popular spa hotels in San Francisco include Megapolis Hotel Panamá and Las Americas Golden Tower Panama.
How many spa hotels will I find in San Francisco?
Among Expedia’s 195 accommodation options in San Francisco, there are 4 spa hotels.
What's there to see and do in San Francisco?
Enjoy San Francisco and visit Multiplaza Pacific Mall, Calle 50, and Avenida Balboa. If you have spare time during your trip, you might want to make a stop at Panama Canal Murals and Pacific Center.
What is a San Francisco spa hotel?
Spa hotels in San Francisco provide lodging and have an on-site spa which offers services like therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.