Photo by Hideki Yamagata

Find Resorts & Hotels with Spas in San Francisco

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Pick from 11 San Francisco Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Sheraton Grand Panama
Exterior
Sheraton Grand Panama
4.0 star property
8.4 out of 10, Very Good, (816)
"The front desk staff was extremely hepful with suggestions of local tours and experiences. They were also quite thoughtful- sent a birthday cake to my mom's room. They added joy to our overall experience "
The price is AED 501
AED 552 total
includes taxes & fees
23 Nov - 24 Nov
Sheraton Grand Panama
JW Marriott Panama
Pool
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Professional and friendly staff. "
The price is AED 555
AED 601 total
includes taxes & fees
7 Dec - 8 Dec
JW Marriott Panama
Aloft Panama
Outdoor pool
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (763)
"Beautiful. Great. 10/10. Had a cancelled flight and this was great and I’m a really great area. I’d stay here again for a couple of nights. "
The price is AED 450
AED 495 total
includes taxes & fees
24 Nov - 25 Nov
Aloft Panama
Residence Inn by Marriott Panama City
Exterior
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (388)
"It was a very vice stay for my family and I. "
The price is AED 433
AED 470 total
includes taxes & fees
6 Dec - 7 Dec
Residence Inn by Marriott Panama City
Megapolis Hotel Panamá
Front of property
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very Good, (690)
"Breakfast was good. Staff very helpful. Megapolis mall was somewhat empty. Not a lot of stores operating. However the Multiplaza Mall nearby was excellent. "
The price is AED 441
AED 485 total
includes taxes & fees
28 Nov - 29 Nov
Megapolis Hotel Panamá
Courtyard by Marriott Panama Multiplaza Mall
Exterior
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1011)
"👌"
The price is AED 592
AED 644 total
includes taxes & fees
6 Dec - 7 Dec
Courtyard by Marriott Panama Multiplaza Mall
Ramada Plaza By Wyndham Panama Punta Pacífica
Exterior
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1003)
"It was a nice hotel, the breakfast buffet was good and was close to a lot of restaurants and the Mall "
The price is AED 411
AED 453 total
includes taxes & fees
28 Nov - 29 Nov
Ramada Plaza By Wyndham Panama Punta Pacífica
Decapolis Hotel Panama City
Front of property
Decapolis Hotel Panama City
4.0 star property
8.6 out of 10, Excellent, (1007)
"location"
The price is AED 295
AED 325 total
includes taxes & fees
10 Dec - 11 Dec
Decapolis Hotel Panama City
Diaphanous Urban Apartment
Living area
Diaphanous Urban Apartment
3.5 star property
9.2 out of 10, Wonderful, (5)
"The apartment is nice but could definitely use some love! Details like the missing shower caddy, missing bathroom sink plug, broken kitchen stools, half-broken AC remote and others took an impact on the comfort, but it was overall still nice. The WiFi was very fast and convenient. If you plan on ordering food, make sure to add that it must be brought up to the apartment door. The check-in took a long time as the security guard (no "front desk", just a security guard booth) was very confused,...
Diaphanous Urban Apartment
Delightful Apartment City Center
Terrace/patio
Delightful Apartment City Center
3.5 star property
10.0 out of 10, Exceptional, (2)
"Delightful is true, great location! Awesome rooftop pool. Everything you need is a short walk or quick Uber away. Close enough to tourist attractions but far enough away to enjoy local cuisine and culture."
Delightful Apartment City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in San Francisco?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Be sure to enjoy the many popular restaurants during your stay. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in San Francisco?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a rooftop terrace. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in San Francisco include Decapolis Hotel Panama City and Las Americas Golden Tower Panama.
How many spa hotels will I find in San Francisco?
Among Expedia’s 177 accommodation options in San Francisco, there are 4 spa hotels.
What's there to see and do in San Francisco?
Enjoy San Francisco and visit Multiplaza Pacific Mall, Calle 50, and Avenida Balboa. If you have spare time during your trip, you might want to make a stop at Multicentro Panama and Panama Canal Murals.
What is a San Francisco spa hotel?
Spa hotels in San Francisco provide lodging and have an on-site spa which offers services like therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.