Find Resorts & Hotels with Spas in Panama City
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Panama City Resorts & Hotels with Spas
Compare Panama City Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
8.8 out of 10, Excellent, (921)
The price is AED 621
AED 683 total
includes taxes & fees
16 Mar - 17 Mar

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (553)
The price is AED 902
AED 992 total
includes taxes & fees
4 Apr - 5 Apr

Marriott Panama Hotel
Marriott Panama Hotel
9.0 out of 10, Wonderful, (1003)
The price is AED 400
AED 440 total
includes taxes & fees
14 Mar - 15 Mar

Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1000)
The price is AED 621
AED 683 total
includes taxes & fees
11 Apr - 12 Apr

W Panama
W Panama
8.8 out of 10, Excellent, (1000)
The price is AED 702
AED 772 total
includes taxes & fees
11 Apr - 12 Apr

Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (411)
The price is AED 1,140
AED 1,254 total
includes taxes & fees
10 Apr - 11 Apr

Sheraton Grand Panama
Sheraton Grand Panama
8.6 out of 10, Excellent, (848)
The price is AED 522
AED 574 total
includes taxes & fees
22 Mar - 23 Mar

Hilton Panama
Hilton Panama
8.8 out of 10, Excellent, (1000)
The price is AED 782
AED 860 total
includes taxes & fees
5 Apr - 6 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Panama City
Find out more about Panama City
Recent reviews of Panama City hotels
Recent reviews of Panama City hotels

Hotel Riu Plaza Panama
5/5 Excellent
"The staff is great! Super nice hotel! Awesome location. Many dining options. We ate by the pool one nite, had sushi one nite, ate at Tastes one night. The 24 hr cafe is awesome. The free breakfast is the most amaxong layout of fodd ive ever seen. Our room was spotless and big! We had a 1 bedroom suite. View from our room was awesome. Tour and ticket assistance awesome! I highly recommend this hotel."
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 9 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Resorts & Hotels with Spas
- Resorts & Hotels with Spas in Casco Viejo
- Resorts & Hotels with Spas in Bella Vista
- Resorts & Hotels with Spas in El Cangrejo
- Resorts & Hotels with Spas in San Francisco
- Resorts & Hotels with Spas in Calidonia
- Resorts & Hotels with Spas in Punta Paitilla
- Resorts & Hotels with Spas in Costa del Este
- Resorts & Hotels with Spas in Marbella
- Resorts & Hotels with Spas in Punta Pacifica
More Hotel Options in Panama City
- Adults Only Resorts & Hotels in Panama City
- Adventure Hotels in Panama City
- All-inclusive Hotel in Panama City
- Beach Hotels in Panama City
- Boutique Hotels in Panama City
- Business Hotels in Panama City
- Casinos in Panama City
- Cheap Hotels in Panama City
- Family Hotels in Panama City
- Golf Hotels in Panama City
- Green Hotels in Panama City
- Historic Hotels in Panama City
- Hotel Wedding Venues in Panama City
- Hotel with a Concierge in Panama City
- Hotels with Bars in Panama City
- Hotels with Early Check-in in Panama City
- Hotels with Free Parking in Panama City
- Hotels with Hot Tubs in Panama City
- Hotels with WiFi in Panama City
- Hotels with a Pool in Panama City
- Hotels with an Indoor Pool in Panama City
- Hotels with smoking rooms in Panama City
- Luxury Hotels in Panama City
- Pet-friendly Hotels in Panama City
- Romantic Hotels in Panama City
- Shopping Hotels in Panama City
- Ski Hotels in Panama City
- Waterpark Hotels in Panama City
- Winery Hotels in Panama City
More Accommodation Types in Panama City
- Apartments in Panamá Province
- Condo Rentals in Panamá Province
- Vacation Homes in Panamá Province
- Hostels in Panamá Province
- Aparthotels in Panamá Province
- B&B in Panamá Province
- Guest Houses in Panamá Province
- Lodges in Panamá Province
- Cabin Rentals in Panamá Province
- Villas in Panamá Province
- Farmstay in Panamá Province
- RV Parks in Panamá Province
- Cottages in Panamá Province
- Resorts in Panamá Province
- Castles in Panamá Province
- Houseboats in Panamá Province
- Inns in Panamá Province
- Pensions in Panamá Province
Hotels near popular Panama City Attractions
Panama City Hotels by Star Rating
Explore more hotels
- The Executive Hotel
- Riande Urban Hotel
- Hotel Ojos del Rio
- Megapolis Hotel Panamá
- Hilton Panama
- Waymore Hotel Spa & Casino
- TRYP by Wyndham Panamá Centro
- Bristol Panama, a Registry Collection Hotel
- Las Americas Golden Tower Panama
- Hospedium Princess Hotel Panama
- Sofitel Legend Casco Viejo, Panama City
- AC Hotel by Marriott Panama City
- MARINN PLACE Financial District
- Sheraton Grand Panama
- Central Hotel Panama Casco Viejo
- Holiday Inn Panama Distrito Financiero by IHG
- Hotel La Compania, in the Unbound Collection by Hyatt
- American Trade Hotel
- Hotel Costa Inn
- Studio Coliving
Expedia's Latest Trends
Hotels
Flights
Flights to EasthopeFlights to BroadstoneFlights to AtchamFlights to DetchantFlights to BranscombeFlights to TywardreathFlights to TredunnockFlights to TingrithFlights to BoxgroveFlights to StokesleyFlights to Great SalkeldFlights to CriggionFlights to PonsanoothFlights to HacilarFlights to Down ThomasFlights to RowtonFlights to BrockworthFlights to DartingtonFlights to BosburyFlights to BostanFlights to LochdonFlights to Toy's HillFlights to MarkyateFlights to AltarnunFlights to GuzelcehisarFlights to SirnakFlights to Skeyton