Photo by Hideki Yamagata

Find 5 Star Hotels in San Francisco from AED 310

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Check availability on San Francisco 5 Star Hotels

Tonight
1 Apr - 2 Apr
Tomorrow
2 Apr - 3 Apr
This weekend
4 Apr - 6 Apr
Next weekend
11 Apr - 13 Apr

Compare San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4083)
"Nice hotel and recommended "
The price is AED 422
AED 465 total
includes taxes & fees
29 Apr - 30 Apr
Hotel Riu Plaza Panama
W Panama
Marvelous Suite, Suite, 1 King Bed, Non Smoking, City View | In-room safe, blackout drapes, iron/ironing board

W Panama

5.0 star property
8.8 out of 10, Excellent, (1133)
"Amazinggg place ! Def would book again"
The price is AED 585
AED 643 total
includes taxes & fees
2 May - 3 May
W Panama
Waldorf Astoria Panama
Outdoor pool, pool umbrellas, sun loungers

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1060)
"Excellent location and easy access to restaurants, shopping and sea wall. Hotel staff were always friendly and eager to assist."
The price is AED 809
AED 889 total
includes taxes & fees
13 Apr - 14 Apr
Waldorf Astoria Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1161)
"Love the staff"
The price is AED 673
AED 740 total
includes taxes & fees
2 May - 3 May
JW Marriott Panama
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, steam room, Turkish bath, body treatments

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1107)
"Only place I stay "
The price is AED 578
AED 635 total
includes taxes & fees
1 May - 2 May
Bristol Panama, a Registry Collection Hotel
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (419)
"It’s a beautiful hotel and the service is exceptional. The pool area and the views are very special. I would also like to commend some of the staff who were most helpful and friendly during my stay. Julissa in room service was very friendly and genuinely committed to her guests, a smiling face to greet me each morning. Jesus at the front desk and Shaun both went above and beyond to help answer my questions and replace a lost key. The staff represent the hotel and the warm and friendly country of...
The price is AED 1,074
AED 1,182 total
includes taxes & fees
21 Apr - 22 Apr
Sofitel Legend Casco Viejo, Panama City
The Westin Playa Bonita Panama
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1098)
"Location was great. Easy 45 minute ride from the international airport and less than that to local attractions. Food was great at the hotel and always had plenty of options for adults and children. Note: We had the premium package and would recommend. Kudos to the staff for keeping the property, rooms and pools clean at this large facility. "
The price is AED 720
AED 792 total
includes taxes & fees
1 May - 2 May
The Westin Playa Bonita Panama
Hilton Panama
Outdoor pool

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1129)
"This was a very nice property and location. Next time I would stay in Casco Viejo because everything was there. This was a great location as well especially if you’re looking for a quieter area."
The price is AED 730
AED 803 total
includes taxes & fees
2 May - 3 May
Hilton Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (554)
"This is a beautiful hotel with amazing staff and everything exceeding our expectations "
The price is AED 780
AED 858 total
includes taxes & fees
18 Apr - 19 Apr
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Renaissance Panama City Hotel
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

5.0 star property
7.6 out of 10, Good, (865)
"Nightlife"
The price is AED 437
AED 481 total
includes taxes & fees
12 Apr - 13 Apr
Renaissance Panama City Hotel
Veneto Hotel & Casino
Outdoor pool

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (998)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Francisco.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is AED 397 per night from Apr 25 to Apr 26
AED 397
AED 497 total
includes taxes & fees
25 Apr - 26 Apr
8.4/10 Very Good! (2,092 reviews)
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Frequently asked questions

What are the best 5-star hotels in San Francisco?
JW Marriott Panama is among the most popular picks around the Panama City neighborhood of San Francisco based on Expedia customer reviews. The Bahia Grand Hotel and Bristol Panama, a Registry Collection Hotel are other 5-star hotels in this area that rank highest with guests.
How much does it cost to stay in a 5-star hotel in San Francisco?
There are a variety of pricing options for 5-star hotels in San Francisco on Expedia. How much you’ll pay will depend on when you travel, length of stay and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to score the ideal upscale stay.

  • Search for the lowest price per night from AED 310

What makes a hotel 5 stars in San Francisco?
Faultless guest service is the foundation of every 5-star hotel in San Francisco. From the minute you step through the door, staff ensure your every need is met, whether recommending activities or providing in-room massage treatments. Additionally, hotels have to feature upscale amenities to be considered for a 5-star rating. These can include luxury toiletries, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in San Francisco?
Expedia’s filter tool is the easiest way to find exactly what you want. Check the “All inclusive” and “5-star” boxes to show the most luxurious hotels in San Francisco where your accommodations, meals, activities and entertainment are included in the upfront price. At these getaways, your vacation is pure relaxation and indulgence from the moment you arrive.
What are the top 5-star spa hotels in San Francisco?
Enjoy a wide range of spa treatments, therapies and amenities at Bristol Panama, a Registry Collection Hotel. Alternatively, prioritize your health and well-being and focus on self-care at The Bahia Grand Hotel or JW Marriott Panama. These premium 5-star spa properties are located in or near San Francisco.
Are there any 5-star vacation rentals in San Francisco?
Although there aren’t any 5-star vacation rentals in San Francisco on our site, we have a range of escapes that promise a fabulous getaway. Find one that matches your needs by checking out our vacation rentals in San Francisco.