Photo by Hideki Yamagata

Find 5 Star Hotels in San Francisco from AED 300

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Compare San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3428)
"The only thing that I didn’t like was that you don’t provide enough water, only 2 bottles of water in a hot city is kind of cheap."
The price is AED 437
AED 481 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Riu Plaza Panama

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1004)
"Beautiful hotel in nice location. Room was spacious and comfortable. TV didn’t work. No ice is a problem. Minibar is ridiculous and takes up entire fridge space. Lobby Restaurant menu has only a few items. Breakfast Buffet is excellent."
The price is AED 621
AED 683 total
includes taxes & fees
3 Jan - 4 January 2025
Waldorf Astoria Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1005)
"Soooo amazing! Loved this hotel it’s like mini Dubai if you’ve ever been to aura sky pool! Beautiful and amazing stay! "
The price is AED 768
AED 844 total
includes taxes & fees
10 Jan - 11 January 2025
JW Marriott Panama

W Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"The property and room was amazing!!! The staff were very friendly and helpful. "
The price is AED 592
AED 651 total
includes taxes & fees
10 Jan - 11 January 2025
W Panama

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1003)
"Property was nice. People were friendly. Didn’t care for any of the food at the restaurants so I opted not to get the all inclusive option. Pools close at 7pm. They are very clean though. The worst part is that o stayed on the six floor and there was this disgusting smell each day at certain times of the day in the hall and also on the room. Eventually I would become nose blind to it but it was heinous. Very relaxing g property though. "
The price is AED 740
AED 814 total
includes taxes & fees
19 Jan - 20 January 2025
The Westin Playa Bonita Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"Shouldn’t charge for parking if you’re a guest plus hilton member. Wrong. For the rest everything is fine "
The price is AED 621
AED 683 total
includes taxes & fees
4 Jan - 5 January 2025
Hilton Panama

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (359)
"El hotel es hermoso. Tiene muchos detalles. El diseño y la arquitectura. La ubicación. Es como en las fotos. La gente muy servicial. Puedes pedir cualquier comida de la carta las 24 horas del día y te lo llevan a la habitación. Nuestra habitación tenía un balcón bello en donde nos colocaron una mesa rodante de donde venía la comida que ordenamos. Muy especial. La cama y almohadas muy cómodas. Estilo colonial hermoso! "
The price is AED 1,322
AED 1,454 total
includes taxes & fees
6 Jan - 7 January 2025
Sofitel Legend Casco Viejo, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (521)
"A very classy and chic Hotel that exceeded my expectations. The customer service and customer care are exceptional. Andrea, who works at the front desk, was so helpful and accommodating to us. The rooms are bright, big and very clean. Lobby area is very nicely decorated. Breakfast was amazing, there was nothing you could not find there. "
The price is AED 731
AED 804 total
includes taxes & fees
4 Jan - 5 January 2025
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1000)
"Well handled reception process. Very nicely appointed rooms."
The price is AED 611
AED 672 total
includes taxes & fees
3 Jan - 4 January 2025
Bristol Panama, a Registry Collection Hotel

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (997)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Frequently asked questions

What are the best 5-star hotels in San Francisco?
JW Marriott Panama is among the most popular picks around the Panama City neighborhood of San Francisco based on Expedia customer reviews. The Bahia Grand Hotel and Bristol Panama, a Registry Collection Hotel are other 5-star hotels in this area that rank highest with guests.
How much does it cost to stay in a 5-star hotel in San Francisco?
There are a variety of pricing options for 5-star hotels in San Francisco on Expedia. How much you’ll pay will depend on when you travel, length of stay and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to score the ideal upscale stay.

  • Search for the lowest price per night from AED 300

What makes a hotel 5 stars in San Francisco?
Faultless guest service is the foundation of every 5-star hotel in San Francisco. From the minute you step through the door, staff ensure your every need is met, whether recommending activities or providing in-room massage treatments. Additionally, hotels have to feature upscale amenities to be considered for a 5-star rating. These can include luxury toiletries, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in San Francisco?
Expedia’s filter tool is the easiest way to find exactly what you want. Check the “All inclusive” and “5-star” boxes to show the most luxurious hotels in San Francisco where your accommodations, meals, activities and entertainment are included in the upfront price. At these getaways, your vacation is pure relaxation and indulgence from the moment you arrive.
What are the top 5-star spa hotels in San Francisco?
Enjoy a wide range of spa treatments, therapies and amenities at Bristol Panama, a Registry Collection Hotel. Alternatively, prioritize your health and well-being and focus on self-care at The Bahia Grand Hotel or JW Marriott Panama. These premium 5-star spa properties are located in or near San Francisco.
Are there any 5-star vacation rentals in San Francisco?
Although there aren’t any 5-star vacation rentals in San Francisco on our site, we have a range of escapes that promise a fabulous getaway. Find one that matches your needs by checking out our vacation rentals in San Francisco.