San Francisco

Panama City
Photo by Hideki Yamagata
Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Nóra Széll
Photo by Panama Roadrunner
Photo by Panama Roadrunner

Popular places to visit

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4.5/5(456 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
This resort is the place to go on the happening Isla Flamenco. Inside you'll find a Duty Free store, a pick & mix candy buffet called Sweet Day, and several restaurants. Not to mention a stunning view of the Flamenco Marina & the Panama City skyline. Did you know that Fort Amador was actually a US army base, built to protect the Panama Canal? When the US pulled out

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

4.5/5(783 reviews)

Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Miraflores Locks
Panama City skyline during the day #seetheworld

Uruguay Street

4/5(59 reviews)

During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.

Uruguay Street

San Francisco Hotel Deals

Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is AED 295 per night from Dec 9 to Dec 10
AED 295
AED 325 total
includes taxes & fees
9 Dec - 10 Dec
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,006 reviews)
"location"

Reviewed on 20 November 2024

Decapolis Hotel Panama City
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is AED 555 per night from Dec 13 to Dec 14
AED 555
AED 601 total
includes taxes & fees
13 Dec - 14 Dec
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,002 reviews)
"Professional and friendly staff."

Reviewed on 22 November 2024

JW Marriott Panama
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
The price is AED 441 per night from Nov 27 to Nov 28
AED 441
AED 485 total
includes taxes & fees
27 Nov - 28 Nov
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (691 reviews)
"I had a wonderful stay! The buffet was excellent, offering a wide variety of choices to suit different tastes. The bed was super comfy, and the modern room was both stylish and functional, complete with a mini fridge for added convenience. Free valet parking was a great bonus, and the location couldn't ..."

Reviewed on 22 November 2024

Megapolis Hotel Panamá
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AED 523 per night from Dec 15 to Dec 16
AED 523
AED 576 total
includes taxes & fees
15 Dec - 16 Dec
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,006 reviews)
"Everything was above and beyond 💯👍"

Reviewed on 23 November 2024

Las Americas Golden Tower Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
The price is AED 386 per night from Nov 27 to Nov 28
AED 386
AED 424 total
includes taxes & fees
27 Nov - 28 Nov
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,003 reviews)
"It was a nice hotel, the breakfast buffet was good and was close to a lot of restaurants and the Mall"

Reviewed on 21 November 2024

Ramada Plaza By Wyndham Panama Punta Pacífica
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
4 out of 5
CALLE RAMON H JURADO EDIFICO P, Panama City
The price is AED 433 per night from Dec 6 to Dec 7
AED 433
AED 470 total
includes taxes & fees
6 Dec - 7 Dec
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (388 reviews)
"It was a very vice stay for my family and I."

Reviewed on 17 November 2024

Residence Inn by Marriott Panama City
See all 1,342 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around San Francisco

Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Obarrio

4/5(91 area reviews)

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Bingo 90 while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
Hard Rock Hotel Panama #StunningStructures

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Multicentro Panama and Avenida Balboa while you're in town.

Punta Paitilla
Default Image

Campo Alegre

4/5(368 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Panama viejo

El Cangrejo

4/5(530 area reviews)

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Marbella

5/5(2 area reviews)

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella

San Francisco

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