Find 5 Star Hotels in Panama City from AED 295

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Compare Panama City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (3242)
"The ambiance and the staff was very friendly."
The price is AED 386
AED 424 total
includes taxes & fees
6 Nov - 7 Nov
Hotel Riu Plaza Panama
Waldorf Astoria Panama
Room
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (994)
"The staff was the absolute best part of the whole experience. The front desk ladies and valet parking guys were super friendly and helpful and always ready to go above and beyond "
The price is AED 555
AED 611 total
includes taxes & fees
23 Nov - 24 Nov
Waldorf Astoria Panama
JW Marriott Panama
Pool
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1012)
"Nice"
The price is AED 614
AED 665 total
includes taxes & fees
22 Nov - 23 Nov
JW Marriott Panama
W Panama
Exterior
W Panama
5.0 star property
8.8 out of 10, Excellent, (1004)
"Property was very clean and nice! "
The price is AED 585
AED 633 total
includes taxes & fees
17 Nov - 18 Nov
W Panama
Sofitel Legend Casco Viejo, Panama City
Exterior detail
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (330)
"Great hotel. Made us feel very special"
The price is AED 1,074
AED 1,182 total
includes taxes & fees
10 Nov - 11 Nov
Sofitel Legend Casco Viejo, Panama City
Hilton Panama
Room
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1007)
"Nice"
The price is AED 511
AED 562 total
includes taxes & fees
6 Dec - 7 Dec
Hilton Panama
Bristol Panama, a Registry Collection Hotel
Room
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1007)
"My time at Bristol was spent relaxing and enjoying the area. The staff were so friendly and welcoming. I highly recommend the Bristol."
The price is AED 621
AED 683 total
includes taxes & fees
6 Dec - 7 Dec
Bristol Panama, a Registry Collection Hotel
The Westin Playa Bonita Panama
Exterior
The Westin Playa Bonita Panama
5.0 star property
8.0 out of 10, Very Good, (994)
"Geeat stay would come back for sure"
The price is AED 611
AED 663 total
includes taxes & fees
5 Dec - 6 Dec
The Westin Playa Bonita Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Pool
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (508)
"."
The price is AED 715
AED 778 total
includes taxes & fees
5 Dec - 6 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Veneto Hotel & Casino
Pool
Veneto Hotel & Casino
5.0 star property
6.2 out of 10, (997)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro, Panama City, Panama
The price is AED 295 per night from Nov 18 to Nov 19
AED 295
AED 325 total
includes taxes & fees
18 Nov - 19 Nov
8.4/10 Very Good! (1,012 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Panama City?
Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are some of the top 5-star hotels in Panama City, based on reviews by our customers. These swanky hotels rate highly for things like their location, amenities and guest service standards. Pick your favorite and enjoy the best of it all.
How much does it cost to stay in a 5-star hotel in Panama City?
The amount you pay for a 5-star hotel in Panama City depends on factors such as when you plan to travel and the length of your escape. An insider tip for landing an awesome deal? Use our pricing filters to check out all of the available hotels for your preferred dates.

  • Search for the lowest price per night from AED 295

What makes a hotel 5 stars in Panama City?
In Panama City, a hotel needs to provide a specific amount of upscale conveniences to earn a 5-star rating. These can include on-site gyms, saunas and spas, gourmet restaurants, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their guest-focused service. You’ll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may even offer thoughtful touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Panama City?
Our filter tool is the quickest way to narrow down what you’re looking for. Check the “All inclusive” and “5-star” boxes to show the most luxurious hotels in Panama City where your room, meals, activities and entertainment are included in the upfront price. At these stays, your vacation is pure indulgence from the moment you put down your suitcase.
What are the top 5-star spa hotels in Panama City?
Recharge your batteries with a decadent massage and other rejuvenating treatments at Waldorf Astoria Panama. It’s one of Panama City’s most popular 5-star spa escapes. W Panama and Bristol Panama, a Registry Collection Hotel also blend upmarket accommodations with a range of wellness therapies.
Are there any 5-star vacation rentals in Panama City?
There are no 5-star vacation rentals in Panama City on our site, but there are a range of other highly rated properties worth looking into. Scan through our vacation rentals in Panama City to book the perfect place for your getaway.
Are there any 5-star hotels in downtown Panama City?
Base yourself at Bristol Panama, a Registry Collection Hotel and take advantage of being near the sights and sounds of downtown Panama City.
What are the top 5-star hotels near Marcos A. Gelabert Intl. Airport (PAC)?
Take the stress out of early or late flights and book Villa Palma Boutique Hotel for your next visit to Panama City. Conveniently located 6 kilometers southeast of Marcos A. Gelabert Intl. Airport (PAC), you’ll look forward to having extra time in your schedule to indulge in the quality perks this 5-star escape has to offer.