Find 5 Star Hotels in Panama City from AED 300

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Compare Panama City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3452)
"Love the breakfast "
The price is AED 422
AED 465 total
includes taxes & fees
28 Jan - 29 January 2025
Hotel Riu Plaza Panama
Waldorf Astoria Panama
Room

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1000)
"beautiful hotel. friendly staff. only complaint i have is the mini bar prices were absolutely ridiculous. the snack prices were insane. "
The price is AED 590
AED 649 total
includes taxes & fees
8 Jan - 9 January 2025
Waldorf Astoria Panama
JW Marriott Panama
View from property

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"Great staff, beautiful pool and view "
The price is AED 804
AED 885 total
includes taxes & fees
31 Jan - 1 February 2025
JW Marriott Panama
W Panama
Exterior

W Panama

5.0 star property
8.8 out of 10, Excellent, (1004)
"It’s a nice hotel, rooms are great and the price very reasonable. But the area around is not very nice and it may be more of a business hotel than a tourist one. I would stay in the old town if I came back. More to walk to and nicer surroundings. But this hotel was nice for what it is. "
The price is AED 658
AED 724 total
includes taxes & fees
11 Jan - 12 January 2025
W Panama
The Westin Playa Bonita Panama
Exterior

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1000)
"The service "
The price is AED 740
AED 814 total
includes taxes & fees
19 Jan - 20 January 2025
The Westin Playa Bonita Panama
Hilton Panama
Room

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"Great location and very professional staff and great service "
The price is AED 621
AED 683 total
includes taxes & fees
24 Jan - 25 January 2025
Hilton Panama
Sofitel Legend Casco Viejo, Panama City
Exterior detail

Sofitel Legend Casco Viejo, Panama City

5.0 star property
10.0 out of 10, Exceptional, (364)
"Simply amazing service on a world class level!"
The price is AED 1,421
AED 1,564 total
includes taxes & fees
8 Jan - 9 January 2025
Sofitel Legend Casco Viejo, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Exterior

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (525)
"The rooms were very nice and all the staff were great. Paola, Elias, Regi, Regina, Vanessa and several others made our stay very comfortable. The food was great and the Christmas Eve buffet was amazing. Would definitely recommend staying at the Santa Maria. "
The price is AED 768
AED 844 total
includes taxes & fees
24 Jan - 25 January 2025
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Bristol Panama, a Registry Collection Hotel
Exterior

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1000)
"Beautiful property. Wonderful restaurant with delicious food. The spa was superb."
The price is AED 519
AED 571 total
includes taxes & fees
11 Jan - 12 January 2025
Bristol Panama, a Registry Collection Hotel
Veneto Hotel & Casino
Pool

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (997)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro, Panama City, Panama
The price is AED 300 per night from Jan 17 to Jan 18
AED 300
AED 331 total
includes taxes & fees
17 Jan - 18 January 2025
8.4/10 Very Good! (1,003 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Panama City?
Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are some of the top 5-star hotels in Panama City, based on reviews by our customers. These swanky hotels rate highly for things like their location, amenities and guest service standards. Pick your favorite and enjoy the best of it all.
How much does it cost to stay in a 5-star hotel in Panama City?
The amount you pay for a 5-star hotel in Panama City depends on factors such as when you plan to travel and the length of your escape. An insider tip for landing an awesome deal? Use our pricing filters to check out all of the available hotels for your preferred dates.

  • Search for the lowest price per night from AED 300

What makes a hotel 5 stars in Panama City?
In Panama City, a hotel needs to provide a specific amount of upscale conveniences to earn a 5-star rating. These can include on-site gyms, saunas and spas, gourmet restaurants, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their guest-focused service. You’ll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may even offer thoughtful touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Panama City?
Our filter tool is the quickest way to narrow down what you’re looking for. Check the “All inclusive” and “5-star” boxes to show the most luxurious hotels in Panama City where your room, meals, activities and entertainment are included in the upfront price. At these stays, your vacation is pure indulgence from the moment you put down your suitcase.
What are the top 5-star spa hotels in Panama City?
Recharge your batteries with a decadent massage and other rejuvenating treatments at Waldorf Astoria Panama. It’s one of Panama City’s most popular 5-star spa escapes. W Panama and Bristol Panama, a Registry Collection Hotel also blend upmarket accommodations with a range of wellness therapies.
Are there any 5-star vacation rentals in Panama City?
There are no 5-star vacation rentals in Panama City on our site, but there are a range of other highly rated properties worth looking into. Scan through our vacation rentals in Panama City to book the perfect place for your getaway.
Are there any 5-star hotels in downtown Panama City?
Base yourself at Bristol Panama, a Registry Collection Hotel and take advantage of being near the sights and sounds of downtown Panama City.
What are the top 5-star hotels near Marcos A. Gelabert Intl. Airport (PAC)?
Take the stress out of early or late flights and book Villa Palma Boutique Hotel for your next visit to Panama City. Conveniently located 6 kilometers southeast of Marcos A. Gelabert Intl. Airport (PAC), you’ll look forward to having extra time in your schedule to indulge in the quality perks this 5-star escape has to offer.