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Find Resorts & Hotels with Spas in Odessa, FL

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Check availability on Odessa Resorts & Hotels with Spas

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Compare Odessa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn Odessa Trinity

2.5 star property
9.6 out of 10, Exceptional, (859)
"Nice stay!"
The price is AED 465
AED 521 total
includes taxes & fees
11 May - 12 May
Hampton Inn Odessa Trinity

Holiday Inn Express & Suites Trinity by IHG

2.5 star property
9.0 out of 10, Wonderful, (660)
"Very nice hotel places is clean and the pool was nice "
The price is AED 433
AED 485 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express & Suites Trinity by IHG

Adorable Waterfront Cottage

9.8 out of 10, Exceptional, (15)
"Michael’s place was great and he was super accommodating! "
The price is AED 437
AED 993 total
includes taxes & fees
2 May - 3 May
Adorable Waterfront Cottage

The Robins Nest|Lakefront Home w/ Pool & Theater

10.0 out of 10, Exceptional, (1)
"The house was beautiful , the scenery was even prettier. We really enjoyed the property and its beautiful views and peacefulness. The house itself was very nice and had everything we needed. Beds were comfy very spacious for us all. Our favorite was the outdoor beauty dock and lake view with beautiful oak trees with Spanish moss on the property it was very nice. "
The Robins Nest|Lakefront Home w/ Pool & Theater

Charming cottage in old Florida Odessa lake community with AC, WiFi, kayak

9.8 out of 10, Exceptional, (8)
"This little place was beautiful and clean and the perfect location! We loved it and wished we were able to stay longer. Our host was phenomenal and responsive to communications."
Charming cottage in old Florida Odessa lake community with AC, WiFi, kayak

8 Mi to Tarpon Springs Sponge Docks: Home w/ Grill

10.0 out of 10, Exceptional, (1)
"The location was perfect for us. Loved the country feel (horse and goat for neighbors ) . Courtyard was grand. The floorplan and kitchen layout was awkward. Couldn't watch much TV because we didn't have app passwords.Overall didn't come to watch TV spent most of the day off property. Had a great time."
8 Mi to Tarpon Springs Sponge Docks: Home w/ Grill

Five Star Rating Lake/WaterFront Oasis Near Tampa/Orlando & Gulf Beaches

10.0 out of 10, Exceptional, (38)
"Lovely location and looked just like pics"
Five Star Rating Lake/WaterFront Oasis Near Tampa/Orlando & Gulf Beaches

Odessa Lakeside: 3BR Pool & Hot Tub

Odessa Lakeside: 3BR Pool & Hot Tub

Luxurious Home w/ Private Pool & Lanai Near Tampa!

9.6 out of 10, Exceptional, (17)
"From start to finish, our 8-day stay in Cleo and John's home was perfect. The booking was easy and communication about the property and its details was prompt and clear. The home is beautifully furnished and spacious. Its layout is perfectly configured and our family of 5 (4 of whom were "working" from home) had plenty of room, both inside and outdoors in the beautiful lenai. The fully equipped kitchen was stocked with our favorite food basics which made our first breakfast after a late night...
Luxurious Home w/ Private Pool & Lanai Near Tampa!

2 kitchens, Canoe, kayak on Sunset Lake + 700sqf apt Perfect for family getaways

8.4 out of 10, Very Good, (24)
"Everything was how we needed it and the property was just right very happy with our stay."
2 kitchens, Canoe, kayak on Sunset Lake + 700sqf apt Perfect for family getaways
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Odessa?
Soothe the senses with some time in one of our wonderful spa hotels. Check out the lakeside setting in Odessa - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
How many spa hotels are there in Odessa?
Among Expedia’s 26 accommodation options in Odessa, there is 1 spa hotel.
What's there to see and do in Odessa?
Enjoy Odessa with a stop at Keystone Lake, Silver Dollar Golf Club, and Old McMicky’s Farm. If you have extra time while you’re in the area, you might want to see Crescent Lake and Brooker Creek Headwaters Nature Preserve.
What is a Odessa spa hotel?
Spa hotels in Odessa have full on-site spas and offer services like therapies and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.