Find Business Hotels in Hannibal, MO
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Hannibal Business Hotels
Compare Hannibal Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

FairBridge Inn Express, Monroe City
FairBridge Inn Express, Monroe City
9.0 out of 10, Wonderful, (363)
The price is AED 331
AED 357 total
includes taxes & fees
17 Apr - 18 Apr

Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
7.8 out of 10, Good, (1011)
The price is AED 328
AED 377 total
includes taxes & fees
27 Apr - 28 Apr

Sleep Inn & Suites
Sleep Inn & Suites
9.6 out of 10, Exceptional, (1013)
The price is AED 426
AED 490 total
includes taxes & fees
20 Apr - 21 Apr

Best Western On The River
Best Western On The River
8.6 out of 10, Excellent, (1013)
The price is AED 375
AED 430 total
includes taxes & fees
6 Apr - 7 Apr

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
6.2 out of 10, (621)
The price is AED 231
AED 266 total
includes taxes & fees
6 Apr - 7 Apr

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
7.6 out of 10, Good, (569)
The price is AED 328
AED 388 total
includes taxes & fees
27 Apr - 28 Apr

Super 8 by Wyndham Bowling Green
Super 8 by Wyndham Bowling Green
8.4 out of 10, Very Good, (441)

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
7.2 out of 10, Good, (1008)
The price is AED 231
AED 266 total
includes taxes & fees
27 Apr - 28 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Hannibal
Find out more about Hannibal
Recent reviews of Hannibal hotels
Recent reviews of Hannibal hotels

Sleep Inn & Suites
5/5 Excellent
"
Quiet, dog friendly, and a great breakfast.
"
A verified traveler stayed at Sleep Inn & Suites
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Hannibal
More Hotel Options in Hannibal
- Adventure Hotels in Hannibal
- Cheap Hotels in Hannibal
- Family Hotels in Hannibal
- Golf Hotels in Hannibal
- Historic Hotels in Hannibal
- Hotel Wedding Venues in Hannibal
- Hotel with a Concierge in Hannibal
- Hotels with Bars in Hannibal
- Hotels with Free Parking in Hannibal
- Hotels with Hot Tubs in Hannibal
- Hotels with WiFi in Hannibal
- Hotels with a Pool in Hannibal
- Hotels with an Indoor Pool in Hannibal
- Hotels with smoking rooms in Hannibal
- Luxury Hotels in Hannibal
- Pet-friendly Hotels in Hannibal
- Resorts & Hotels with Spas in Hannibal
- Romantic Hotels in Hannibal
- Shopping Hotels in Hannibal
More Accommodation Types in Hannibal
- Vacation Homes in Missouri
- Condo Rentals in Missouri
- Apartments in Missouri
- Cabin Rentals in Missouri
- Cottages in Missouri
- Motels in Missouri
- Resorts in Missouri
- Lodges in Missouri
- Chalets in Missouri
- Villas in Missouri
- B&B in Missouri
- Farmstay in Missouri
- Aparthotels in Missouri
- RV Parks in Missouri
- Guest Houses in Missouri
- Inns in Missouri
- Condo Resorts in Missouri
- Hostels in Missouri
- Houseboats in Missouri
- Residences in Missouri
Hotels near popular Hannibal Attractions
- Hotels near Mark Twain Boyhood Home and Museum
- Hotels near Mark Twain Cave
- Hotels near Mark Twain Cave and Cameron Cave
- Hotels near Rockcliffe Mansion
- Hotels near Lovers Leap
- Hotels near Mark Twain Memorial Lighthouse
- Hotels near Jim's Journey: The Huck Finn Freedom Center
- Hotels near Big River Train Town
- Hotels near Molly Brown Museum and Home
- Hotels near Sawyer's Creek Fun Park
Hannibal Hotels by Star Rating
Explore more hotels
- Lighthouse Hospitality Hannibal
- The Indigo House- Located in the heart of Historic Hannibal, Missouri
- Cozy 1895 Victorian, 5 minute walk to historic downtown and Mississippi River
- Garden House Bed and Breakfast
- Admiral Fuqua House - Large downtown Hannibal Home
- Cozy 3 bed, 2 bath home close to historic downtown Hannibal
- Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee
- Holiday Inn Express And Suites Hannibal - Medical Center by IHG
- Garth Woodside Mansion B&B
- Amazing Hannibal Home - Eitaly’s on Paris
- The John Sydney House - Family and Pet Friendly Historic Home Downtown
- Cozy apartment close to downtown Hannibal with full kitchen, A/C, and Wi-Fi
- Modern and comfy home five minutes from downtown
- Hannibal House ~ Walking Distance From Historic District
- Vibey home a few blocks from downtown Hannibal
- Stoney Creek Inn Quincy
- Quincy Inn and Suites
- Town & Country Inn and Suites
- Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
- The Atrium Hotel on Third