Find 4 Star Hotels in Hannibal, MO
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Compare Hannibal 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Best Western On The River
Best Western On The River
8.6 out of 10, Excellent, (1006)
The price is AED 393
AED 451 total
includes taxes & fees
19 Mar - 20 Mar

Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
7.8 out of 10, Good, (1002)
The price is AED 290
AED 333 total
includes taxes & fees
23 Mar - 24 Mar

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
7.6 out of 10, Good, (552)
The price is AED 297
AED 352 total
includes taxes & fees
23 Mar - 24 Mar

Sleep Inn & Suites
Sleep Inn & Suites
9.6 out of 10, Exceptional, (1003)
The price is AED 366
AED 420 total
includes taxes & fees
30 Mar - 31 Mar

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
7.4 out of 10, Good, (1002)
The price is AED 206
AED 236 total
includes taxes & fees
22 Mar - 23 Mar

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
6.2 out of 10, (617)
The price is AED 231
AED 266 total
includes taxes & fees
17 Mar - 18 Mar

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
7.2 out of 10, Good, (1000)
The price is AED 215
AED 247 total
includes taxes & fees
1 Apr - 2 Apr

Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
7.2 out of 10, Good, (138)
The price is AED 220
AED 253 total
includes taxes & fees
13 Apr - 14 Apr
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Hannibal and related destinations
Escape to Hannibal! Enjoy its history, museums, and riverfront.

Explore the historic buildings and museums of this delightful South Carolina city that’s also known for its nature trails and outdoor pursuits.

Katy awaits: its cafes, opera, zoo, and more!

This city in the mid-South combines an outlaw and Wild West heritage with magnificent landscapes and the Arkansas wine country.

Photo by Photo Courtesy Arkansas Department of Parks and Tourism
Open Photo by Photo Courtesy Arkansas Department of Parks and Tourism
Lima awaits: its university life, food, cathedral, and more!

Photo by throwingsofas
Open Photo by throwingsofas
Recent reviews of Hannibal hotels
Recent reviews of Hannibal hotels

Lighthouse Inn & Suites
5/5 Excellent
"It was a very nice room. "
A verified traveler stayed at Lighthouse Inn & Suites
Posted 2 months ago
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Hannibal Hotels by Star Rating
Stay near popular Hannibal attractions
- Hotels near Mark Twain Boyhood Home and Museum
- Hotels near Mark Twain Cave
- Hotels near Mark Twain Cave and Cameron Cave
- Hotels near Rockcliffe Mansion
- Hotels near Lovers Leap
- Hotels near Mark Twain Memorial Lighthouse
- Hotels near Jim's Journey: The Huck Finn Freedom Center
- Hotels near Big River Train Town
- Hotels near Molly Brown Museum and Home
- Hotels near Sawyer's Creek Fun Park
- Hotels near Planters Barn Theater
- Hotels near Bluff City Theater
- Hotels near Sodalis Nature Preserve
- Hotels near Mississippi River
More Hotel Options in Hannibal
- Adventure Hotels in Hannibal
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- Cheap Hotels in Hannibal
- Family Hotels in Hannibal
- Golf Hotels in Hannibal
- Historic Hotels in Hannibal
- Hotel Wedding Venues in Hannibal
- Hotel with a Concierge in Hannibal
- Hotels with Bars in Hannibal
- Hotels with Free Parking in Hannibal
- Hotels with Hot Tubs in Hannibal
- Hotels with WiFi in Hannibal
- Hotels with a Pool in Hannibal
- Hotels with an Indoor Pool in Hannibal
- Hotels with smoking rooms in Hannibal
- Luxury Hotels in Hannibal
- Pet-friendly Hotels in Hannibal
- Resorts & Hotels with Spas in Hannibal
- Romantic Hotels in Hannibal
- Shopping Hotels in Hannibal
More Accommodation Types in Hannibal
Explore more hotels
- Lighthouse Inn & Suites
- The Indigo House- Located in the heart of Historic Hannibal, Missouri
- Holiday Inn Express And Suites Hannibal - Medical Center by IHG
- Admiral Fuqua House - Large downtown Hannibal Home
- Cozy 3 bed, 2 bath home close to historic downtown Hannibal
- Cozy 1895 Victorian, 5 minute walk to historic downtown and Mississippi River
- Amazing Hannibal Home - Eitaly’s on Paris
- Garden House Bed and Breakfast
- Cozy apartment close to downtown Hannibal with full kitchen, A/C, and Wi-Fi
- Modern and comfy home five minutes from downtown
- Garth Woodside Mansion B&B
- The John Sydney House - Family and Pet Friendly Historic Home Downtown
- Hannibal House ~ Walking Distance From Historic District
- Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee
- Vibey home a few blocks from downtown Hannibal
- Stoney Creek Inn Quincy
- Town & Country Inn and Suites
- Quincy Inn and Suites
- Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
- The Atrium Hotel on Third