Find 4 Star Hotels in Hannibal, MO

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Check availability on Hannibal 4 Star Hotels

Compare Hannibal 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1006)
"Very nice facility customer service very good "
The price is AED 393
AED 451 total
includes taxes & fees
19 Mar - 20 Mar
Best Western On The River

Quality Inn & Suites Hannibal

2.5 star property
7.8 out of 10, Good, (1002)
"Very welcoming staff. Breakfast was good. Facility was quite nice. "
The price is AED 290
AED 333 total
includes taxes & fees
23 Mar - 24 Mar
Quality Inn & Suites Hannibal

Comfort Inn & Suites - Hannibal

2.5 star property
7.6 out of 10, Good, (552)
"Nice staff, clean room. Could use some updating. Pool and hot tub were bonuses! "
The price is AED 297
AED 352 total
includes taxes & fees
23 Mar - 24 Mar
Comfort Inn & Suites - Hannibal

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1003)
"No issues. All went well. Quiet, clean."
The price is AED 366
AED 420 total
includes taxes & fees
30 Mar - 31 Mar
Sleep Inn & Suites

Motel 6 Hannibal, MO

2.0 star property
7.4 out of 10, Good, (1002)
"Very clean "
The price is AED 206
AED 236 total
includes taxes & fees
22 Mar - 23 Mar
Motel 6 Hannibal, MO

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (617)
"Staff were kind and accommodating as always! The room was clean and comfortable, I felt safe, I enjoyed a nice shower after a long drive and then got cozied up and watched Tombstone on TV until I fell asleep. I slept well, no noise, just the right temperature in the room. Affordable and comfortable- just what I needed. Will stay again! "
The price is AED 231
AED 266 total
includes taxes & fees
17 Mar - 18 Mar
Baymont by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1000)
"The staff was very nice and helpful!"
The price is AED 215
AED 247 total
includes taxes & fees
1 Apr - 2 Apr
Super 8 by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (138)
"A little older bldg but was clean & staff was very friendly & helpful. Was hoping for some danish at breakfast time - but that’s just me."
The price is AED 220
AED 253 total
includes taxes & fees
13 Apr - 14 Apr
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.0 out of 10, Good, (106)
"The hotel was good for the price. The pool was very big and unique. The floors in the room could have used a bit more cleaning. I was stepping all over rocks and crumbs and dirt and sand and after getting out of the shower and walking to the bed, my feet were dirty and completely black on the bottom. When going to check out, no one was at the front desk to pass the info on and hadn't been for a minute I'm guessing because we just piled our card on the desk with all of the others. Overall it was...
The price is AED 198
AED 228 total
includes taxes & fees
17 Mar - 18 Mar
Howard Johnson BY Wyndham Hannibal

Lighthouse Hospitality Hannibal

2.5 star property
9.2 out of 10, Wonderful, (106)
"Nice location in town, friendly people, historical preserved architecture."
The price is AED 514
AED 717 total
includes taxes & fees
17 Mar - 18 Mar
Lighthouse Hospitality Hannibal

Cozy 1895 Victorian, 5 minute walk to historic downtown and Mississippi River

9.0 out of 10, Wonderful, (6)
"This house is beautiful and cozy just as described. It was very clean. The host, Chris, was very friendly and accommodating. He told us the history of the house and gave us a recommendation for a dining experience at LaBinnah Bistro, which was delicious! We had a good night’s rest & enjoyed lively conversation over breakfast "
The price is AED 437
AED 575 total
includes taxes & fees
28 Mar - 29 Mar
Cozy 1895 Victorian, 5 minute walk to historic downtown and Mississippi River

Garden House Bed and Breakfast

2.0 star property
8.4 out of 10, Very Good, (15)
"The home was so unique and wonderfully decorated. The host was so friendly and had loads of history about the house and the area. Our room was very comfortable. The breakfast was fabulous. "
The price is AED 393
AED 452 total
includes taxes & fees
17 Mar - 18 Mar
Garden House Bed and Breakfast

Garth Woodside Mansion B&B

3.5 star property
9.6 out of 10, Exceptional, (18)
"Awesome room. "
Garth Woodside Mansion B&B

Holiday Inn Express And Suites Hannibal - Medical Center by IHG

2.5 star property
9.8 out of 10, Exceptional, (387)
"Modern and great service. Very welcoming staff. Clean and spacious rooms."
Holiday Inn Express And Suites Hannibal - Medical Center by IHG

Main Street Bed & Breakfast

2.0 star property
9.2 out of 10, Wonderful, (180)
"Fun vintage building in great location. Staff friendly and full of information. "
Main Street Bed & Breakfast

Happy Stay Inn

2.0 star property
Happy Stay Inn
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Hannibal and related destinations

Escape to Hannibal! Enjoy its history, museums, and riverfront.

Explore the historic buildings and museums of this delightful South Carolina city that’s also known for its nature trails and outdoor pursuits.

Katy awaits: its cafes, opera, zoo, and more!

This city in the mid-South combines an outlaw and Wild West heritage with magnificent landscapes and the Arkansas wine country.

Fort Smith
Photo by Photo Courtesy Arkansas Department of Parks and Tourism
Open Photo by Photo Courtesy Arkansas Department of Parks and Tourism

Lima awaits: its university life, food, cathedral, and more!

A frosted malt, fries and a double hamburger from Kewpee Hamburgers.

Of the five remaining Kewpee restaurants, three of them can be found in Lima, OH.

Kewpee hamburgers started in 1923 and this iconic location in downtown Lima opened in 1928.

A Kewpee location in Kalamazoo, MI, near where Wendy's founder Dave Thomas grew up, is said to have inspired him with their square hamburgers and thick shakes.
Photo by throwingsofas
Open Photo by throwingsofas

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Hannibal?
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What's the difference between 5-star and 4-star hotels in Hannibal?
Offering a friendly traveler experience and upmarket décor, 4-star hotels are a great option for your Hannibal getaway. These kinds of stays generally come with lots of useful amenities that make it a breeze to unpack and unwind — think complimentary bathrobes, pools and gyms. Or live the high life at a 5-star hotel designed to indulge you in luxury perks and amenities. On-site health clubs, oversized bathrooms and gourmet dining are typically included at these deluxe retreats.
Does Hannibal have any 4-star all-inclusive resorts?
Use our “All inclusive” filter to find your next dream escape in Hannibal where just about everything is taken care of, from your accommodations to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this sought-after destination.