Find Resorts & Hotels with Spas in Greenville, SC

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Greenville Resorts & Hotels with Spas

Tonight
5 May - 6 May
Tomorrow
6 May - 7 May
This weekend
9 May - 11 May
Next weekend
16 May - 18 May

Compare Greenville Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Embassy Suites Greenville Golf Resort & Conference Center
37-inch flat-screen TV with cable channels, TV, pay movies

Embassy Suites Greenville Golf Resort & Conference Center

3.5 star property
8.8 out of 10, Excellent, (1005)
"Clean and very good location. Breakfast is always amazing and the reason we stay here!"
The price is AED 490
AED 555 total
includes taxes & fees
11 May - 12 May
Embassy Suites Greenville Golf Resort & Conference Center
Hotel Hartness
Interior entrance

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (503)
"Wonderful service and stay"
The price is AED 632
AED 820 total
includes taxes & fees
18 May - 19 May
Hotel Hartness
Embassy Suites by Hilton Greenville Downtown Riverplace
Exterior

Embassy Suites by Hilton Greenville Downtown Riverplace

3.5 star property
9.2 out of 10, Wonderful, (1006)
"We had a wonderful stay!"
The price is AED 576
AED 653 total
includes taxes & fees
26 May - 27 May
Embassy Suites by Hilton Greenville Downtown Riverplace
Drury Inn & Suites Greenville
Indoor pool, outdoor pool

Drury Inn & Suites Greenville

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Comfortable bed, great breakfast selections, helpful staff. "
The price is AED 430
AED 473 total
includes taxes & fees
11 May - 12 May
Drury Inn & Suites Greenville
Hyatt Place Greenville/Downtown
Exterior

Hyatt Place Greenville/Downtown

3.0 star property
9.2 out of 10, Wonderful, (1005)
"I loved that it was near everything and the staff were wonderful. "
The price is AED 466
AED 529 total
includes taxes & fees
26 May - 27 May
Hyatt Place Greenville/Downtown
The Westin Poinsett Greenville
Exterior

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Perfect location for a weekend getaway"
The price is AED 657
AED 745 total
includes taxes & fees
26 May - 27 May
The Westin Poinsett Greenville
Hampton Inn Greenville I-385 - Woodruff Rd.
Premium bedding, down comforters, in-room safe, desk

Hampton Inn Greenville I-385 - Woodruff Rd.

3.0 star property
8.8 out of 10, Excellent, (752)
"nice place and hotel. rooms were nice"
The price is AED 403
AED 456 total
includes taxes & fees
29 May - 30 May
Hampton Inn Greenville I-385 - Woodruff Rd.
Residence Inn by Marriott Greenville Downtown
BBQ/picnic area

Residence Inn by Marriott Greenville Downtown

3.0 star property
9.4 out of 10, Exceptional, (303)
"Love the room set up and the closeness to downtown. "
The price is AED 543
AED 610 total
includes taxes & fees
26 May - 27 May
Residence Inn by Marriott Greenville Downtown
La Quinta Inn & Suites by Wyndham Greenville Haywood
Exterior

La Quinta Inn & Suites by Wyndham Greenville Haywood

3.0 star property
7.4 out of 10, Good, (1007)
"Lovely stay. "
The price is AED 284
AED 313 total
includes taxes & fees
11 May - 12 May
La Quinta Inn & Suites by Wyndham Greenville Haywood
Best Western Plus Greenville I-385 Inn & Suites
Seasonal outdoor pool

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1337)
"Convenient location near dining places."
The price is AED 314
AED 345 total
includes taxes & fees
18 May - 19 May
Best Western Plus Greenville I-385 Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Greenville

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia’s 605 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children’s Museum of the Upstate, and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.