Find Resorts & Hotels with Spas in Greenville Downtown, SC

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Pick from 21 Greenville Downtown Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Embassy Suites by Hilton Greenville Downtown Riverplace
Exterior
Embassy Suites by Hilton Greenville Downtown Riverplace
3.5 star property
9.2 out of 10, Wonderful, (1003)
"What an amazing hotel for the price point!"
The price is AED 555
AED 629 total
includes taxes & fees
22 Dec - 23 Dec
Embassy Suites by Hilton Greenville Downtown Riverplace
Hyatt Place Greenville/Downtown
Exterior
Hyatt Place Greenville/Downtown
3.0 star property
9.2 out of 10, Wonderful, (1003)
"Nice room near downtown area. "
The price is AED 465
AED 527 total
includes taxes & fees
26 Nov - 27 Nov
Hyatt Place Greenville/Downtown
The Westin Poinsett Greenville
Exterior
The Westin Poinsett Greenville
4.0 star property
9.2 out of 10, Wonderful, (1002)
"Wonderful place and staff is incredible! "
The price is AED 621
AED 703 total
includes taxes & fees
24 Nov - 25 Nov
The Westin Poinsett Greenville
Residence Inn by Marriott Greenville Downtown
Exterior
Residence Inn by Marriott Greenville Downtown
3.0 star property
9.4 out of 10, Exceptional, (291)
"My king room was awesome! Huge comfy and had everything we needed. "
The price is AED 559
AED 627 total
includes taxes & fees
15 Dec - 16 Dec
Residence Inn by Marriott Greenville Downtown
Aloft Greenville Downtown
Exterior
Aloft Greenville Downtown
3.0 star property
9.0 out of 10, Wonderful, (1000)
"We were in Greenville for The weekend was very impressed with aloft. Everything was excellent very very pet friendly traveling with our Labradoodle went to Greenville for an event so satisfied we stayed at your resort. We will definitely be back."
The price is AED 476
AED 538 total
includes taxes & fees
27 Nov - 28 Nov
Aloft Greenville Downtown
Grand Bohemian Lodge Greenville, Autograph Collection
Lobby
Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
9.6 out of 10, Exceptional, (258)
"What a perfect weekend. The city is beautiful with a parklike setting."
The price is AED 1,286
AED 1,414 total
includes taxes & fees
12 Dec - 13 Dec
Grand Bohemian Lodge Greenville, Autograph Collection
Homewood Suites by Hilton Greenville Downtown
Exterior
Homewood Suites by Hilton Greenville Downtown
3.0 star property
9.4 out of 10, Exceptional, (780)
"Clean, very pretty, roomy room, comfortable bed! Really have nothing to complain about. The grounds were clean and employees were constantly cleaning. The location of the hotel was great for our needs. We would definitely stay here again."
The price is AED 467
AED 529 total
includes taxes & fees
22 Dec - 23 Dec
Homewood Suites by Hilton Greenville Downtown
Hampton Inn & Suites Greenville-Downtown-RiverPlace
Exterior
Hampton Inn & Suites Greenville-Downtown-RiverPlace
2.5 star property
9.4 out of 10, Exceptional, (1004)
"The staff was very friendly and knowledgeable of the area. Mark (valet) was very helpful about places to eat and our parking options. The check in and out process was quick and easy and I think this is my first time enjoying my breakfast at a hotel in years! The bagel I had was brought in from the Bronx, NY! I would definitely stay here again and recommend it to others. "
The price is AED 467
AED 538 total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Greenville-Downtown-RiverPlace
Hyatt Regency Greenville
Exterior
Hyatt Regency Greenville
3.5 star property
8.6 out of 10, Excellent, (1000)
"I really enjoyed my one night stay. Clean. Updated. Huge tv in the room. "
The price is AED 496
AED 562 total
includes taxes & fees
26 Nov - 27 Nov
Hyatt Regency Greenville
Home2 Suites by Hilton Greenville Downtown
Exterior
Home2 Suites by Hilton Greenville Downtown
3.0 star property
9.2 out of 10, Wonderful, (895)
"Great property"
The price is AED 465
AED 512 total
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton Greenville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Greenville Downtown?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Travelers recommend the riverfront and gourmet restaurants in Greenville Downtown. Enjoy the live music and waterfalls during your vacation. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Greenville Downtown?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant.
How many spa hotels are there in Greenville Downtown?
Among Expedia’s 97 accommodation options in Greenville Downtown, there is 1 spa hotel.
What's there to see and do in Greenville Downtown?
Experience Greenville Downtown and visit The Peace Center, Bon Secours Wellness Arena, and The Children’s Museum of the Upstate. If you have extra time while you’re in the area, you might want to stop by Falls Park on the Reedy and Greenville Zoo.
What is a Greenville Downtown spa hotel?
Spa hotels in Greenville Downtown have on-site spas which offer services including therapies and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.