The Best Business Hotels in Chillicothe, MO from AED 278 in 2025

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Compare Chillicothe Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

"Everyone we encountered during our stay were warm and welcoming. All public areas were clean and kept up. Breakfast was great."

In-room safe, iron/ironing board, cribs/infant beds, rollaway beds

"Hotel room was clean and tidy. Better than some other hotels I’ve stayed at for comparable price. Staff cleaned room and replaced towels daily. Good hot shower. Stayed 5 nights. Was disappointed to hear they are tearing hotel down to build truck stop."

Desk, iron/ironing board, free WiFi, bed sheets

"This property is very nice. The front desk is very helpful and informative "

"Comfortable and very friendly. Here for family funeral."

"Room and breakfast area was very clean. A great place to stay. "

"Nice place"

AED 314 total

includes taxes & fees

14 May - 15 May

Find out more about Chillicothe

Recent reviews of Chillicothe hotels

5/5 Excellent

"Nice place"

A verified traveler stayed at Super 8 by Wyndham Chillicothe

Posted 2 days ago

5/5 Excellent

Best hotel sleep I've had in decades.

"Had to stay the night on business. I was a little nervous since it wasn't a chain hotels but I was surprised by how cozy and quiet it was. They didn't offer USB hubs for charging so bring your ac/dc block and the fridge didn't work too well, but I fell asleep at 8:30pm and didn't move until 8:00am the next day. That never happens to me. It was clean and I slept great. Everything else is a bonus. "

A verified traveler stayed at Comfort Inn Marshall Station

Posted 4 days ago