Photo by Fabiola Tile

Find hotels near Calle 50, Panama City from AED 195

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 1,370 hotels close to Calle 50 with room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (9)
"Very high end hotel with reasonable prices compared to similar hotels in the U.S. Very friendly and servicing staff, and excellent restaurants and gym. Smaller size pool, but very nice outdoor area and spa. "
The price is AED 613
AED 675 total
includes taxes & fees
9 May - 10 May
Hyatt Regency Panama City

Yoo Apartamento

3.0 star property
10.0 out of 10, Exceptional, (5)
"The location and view are amazing! This is a great place to stay."
The price is AED 353
AED 549 total
includes taxes & fees
17 May - 18 May
Yoo Apartamento

San Francisco by Wynwood House

4.0 star property
9.6 out of 10, Exceptional, (37)
"Very neat and lots of restaurants in the area. Mall is close by."
The price is AED 393
AED 525 total
includes taxes & fees
4 May - 5 May
San Francisco by Wynwood House

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1004)
"Great place to stay"
The price is AED 388
AED 427 total
includes taxes & fees
2 Jun - 3 Jun
Ramada Plaza By Wyndham Panama Punta Pacífica

MARINN PLACE Financial District

3.5 star property
9.2 out of 10, Wonderful, (269)
"It was a overall great stay "
The price is AED 387
AED 425 total
includes taxes & fees
4 May - 5 May
MARINN PLACE Financial District

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3871)
"Great location , fabulous outdoor pool , fantastic breakfast"
The price is AED 423
AED 465 total
includes taxes & fees
6 May - 7 May
Hotel Riu Plaza Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1004)
"Excelente hotel "
The price is AED 562
AED 618 total
includes taxes & fees
17 May - 18 May
Bristol Panama, a Registry Collection Hotel

Casa Bianca

2.0 star property
10.0 out of 10, Exceptional, (3)
"Good place , nice, clean, "
The price is AED 588
AED 646 total
includes taxes & fees
10 May - 11 May
Casa Bianca

The Executive Hotel

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Great Hotel."
The price is AED 411
AED 453 total
includes taxes & fees
6 May - 7 May
The Executive Hotel

Hostal Familiar Carmencita - Hostel

2.0 star property
9.0 out of 10, Wonderful, (7)
The price is AED 195
AED 214 total
includes taxes & fees
6 May - 7 May
Hostal Familiar Carmencita - Hostel

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1000)
"It was quiet staff very helpful worth the stay"
The price is AED 476
AED 524 total
includes taxes & fees
16 May - 17 May
Courtyard by Marriott Panama Multiplaza Mall

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1014)
"I had a very nice stay."
The price is AED 312
AED 343 total
includes taxes & fees
11 May - 12 May
Novotel Panama City

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
8.8 out of 10, Excellent, (943)
"Beautiful hotel "
The price is AED 547
AED 602 total
includes taxes & fees
1 Jun - 2 Jun
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Nomada Container Hotel Panama City

3.0 star property
8.8 out of 10, Excellent, (132)
"The location was perfect"
The price is AED 220
AED 242 total
includes taxes & fees
16 May - 17 May
Nomada Container Hotel Panama City

Hotel Mio Panama

3.0 star property
9.0 out of 10, Wonderful, (98)
"Great place to stay."
The price is AED 215
AED 338 total
includes taxes & fees
7 May - 8 May
Hotel Mio Panama

Principe Hotel and Suites

3.0 star property
8.8 out of 10, Excellent, (1323)
"Great, low frills easy booking. "
The price is AED 215
AED 236 total
includes taxes & fees
4 May - 5 May
Principe Hotel and Suites

Best Western Plus Panama Zen Hotel

4.0 star property
9.0 out of 10, Wonderful, (846)
"Good hotel for the price. Well located."
The price is AED 284
AED 312 total
includes taxes & fees
19 May - 20 May
Best Western Plus Panama Zen Hotel

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1003)
"Very nice and clean hotel, "
The price is AED 530
AED 583 total
includes taxes & fees
11 May - 12 May
Las Americas Golden Tower Panama

Waymore Hotel Spa & Casino

4.0 star property
9.0 out of 10, Wonderful, (246)
"Loved our stay at Waymore. Property was clean and all staff were great. "
The price is AED 314
AED 345 total
includes taxes & fees
16 May - 17 May
Waymore Hotel Spa & Casino

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2026)
"Family enjoyed their stay"
The price is AED 404
AED 445 total
includes taxes & fees
13 May - 14 May
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Calle 50
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's the area like around Calle 50?

Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 396 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Calle 50?

Hotel Riu Plaza Panama is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and free breakfast. It's located just a short 0.5 mi (0.7 km) from Calle 50. Other good options close by include Principe Hotel and Suites and Riande Urban Hotel.

How many hotels will I be able to find near Calle 50?

Expedia has 396 hotels and other accommodations within a mile from Calle 50.

If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?

Yes! Most hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals available near Calle 50.

Where can I learn more about changing or cancelling my trip in the area near Calle 50?

To find more details about updating your stay near Calle 50 or cancelling it, go to https://www.expedia.com/service/.

What can I see and do near Calle 50?

You'll want to browse the collections at Biomuseo, Colonial Religious Art Museum, and National Bank House Museum. Iglesia del Carmen, Panama Viejo, and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle, and Anita Villalaz Theater.

How can I get to Calle 50?

Local metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore around the surrounding area, you may want a car rental for your journey.